Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/Txe-YefM
Location 218863..219365 Replicon chromosome
Accession NZ_CP011994
Organism Ectothiorhodospira sp. BSL-9

Toxin (Protein)


Gene name relE Uniprot ID A0A166ZWB6
Locus tag ECTOBSL9_RS01055 Protein ID WP_063463503.1
Coordinates 218863..219126 (-) Length 88 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A166ZWC8
Locus tag ECTOBSL9_RS01060 Protein ID WP_063463504.1
Coordinates 219123..219365 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ECTOBSL9_RS01030 214501..215517 - 1017 WP_063463498.1 ketol-acid reductoisomerase -
ECTOBSL9_RS01035 215565..216059 - 495 WP_063463499.1 acetolactate synthase small subunit -
ECTOBSL9_RS01040 216062..217756 - 1695 WP_063463500.1 acetolactate synthase 3 large subunit -
ECTOBSL9_RS01045 217971..218384 + 414 WP_063463501.1 YchJ family protein -
ECTOBSL9_RS01050 218445..218702 - 258 WP_082829661.1 YgiT-type zinc finger protein -
ECTOBSL9_RS01055 218863..219126 - 264 WP_063463503.1 Txe/YoeB family addiction module toxin Toxin
ECTOBSL9_RS01060 219123..219365 - 243 WP_063463504.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
ECTOBSL9_RS01065 219698..222124 - 2427 WP_063463505.1 type I restriction endonuclease subunit R -
ECTOBSL9_RS01070 222121..223125 - 1005 WP_063463506.1 virulence RhuM family protein -
ECTOBSL9_RS01075 223122..224162 - 1041 WP_082829662.1 restriction endonuclease subunit S -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(7-86)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-69)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10216.90 Da        Isoelectric Point: 10.2942

>T55385 WP_063463503.1 NZ_CP011994:c219126-218863 [Ectothiorhodospira sp. BSL-9]
VTWKLVYTKQAQRDARKLTASTLKPKAQELLALIAEDPYRKPPPFEKLVGDLAGAYSRRINIQHRLVYQVLEDERVVKVL
RLWSHYE

Download         Length: 264 bp

>T55385 NZ_CP011994:c219126-218863 [Ectothiorhodospira sp. BSL-9]
GTGACATGGAAGTTGGTTTACACCAAGCAAGCCCAAAGAGATGCAAGGAAGCTGACGGCCAGCACTCTCAAGCCGAAAGC
TCAGGAATTGTTGGCGCTCATTGCAGAAGATCCCTACCGTAAGCCGCCGCCGTTTGAGAAGCTCGTTGGTGATCTTGCAG
GGGCCTATTCGCGTCGCATCAATATTCAGCATCGTCTGGTCTATCAAGTGCTCGAGGACGAGCGAGTGGTGAAGGTGCTC
AGGCTCTGGAGCCACTACGAATAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9024.05 Da        Isoelectric Point: 4.0768

>AT55385 WP_063463504.1 NZ_CP011994:c219365-219123 [Ectothiorhodospira sp. BSL-9]
MAGITATEARSNLYRLIDETAESHQPIVITGKRNTAVLVSEEDWSAIQETLYLLSVPGMRESIREGMETSVDECHEELDW

Download         Length: 243 bp

>AT55385 NZ_CP011994:c219365-219123 [Ectothiorhodospira sp. BSL-9]
ATGGCCGGAATCACAGCAACTGAGGCGCGCAGCAACCTTTATCGGTTGATTGACGAAACGGCTGAATCCCACCAACCTAT
CGTGATCACGGGTAAGCGGAACACAGCGGTTCTGGTATCTGAGGAGGACTGGTCGGCAATTCAGGAAACACTCTATCTGC
TCTCGGTTCCAGGTATGCGAGAGTCTATTCGTGAGGGTATGGAAACCTCTGTGGATGAGTGCCATGAGGAGCTGGACTGG
TGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A166ZWB6

Antitoxin

Source ID Structure
AlphaFold DB A0A166ZWC8

References