Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1913344..1913489 Replicon chromosome
Accession NZ_CP011985
Organism Klebsiella pneumoniae UHKPC07

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1913380..1913482 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1913344..1913489 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H224_RS09495 1908474..1910534 + 2061 WP_032422099.1 oligopeptidase B -
H224_RS09500 1910538..1911197 - 660 WP_002911407.1 exodeoxyribonuclease X -
H224_RS09505 1911276..1911506 - 231 WP_002911406.1 DNA polymerase III subunit theta -
H224_RS09510 1911619..1911993 + 375 WP_004151448.1 CopC domain-containing protein YobA -
H224_RS09515 1911997..1912866 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
H224_RS09520 1912883..1913221 + 339 WP_002911404.1 YebY family protein -
- 1913344..1913489 - 146 - - Antitoxin
- 1913380..1913482 + 103 - - Toxin
H224_RS29810 1913857..1914000 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
H224_RS09530 1914105..1915073 - 969 WP_004151446.1 VirK/YbjX family protein -
H224_RS09535 1915230..1915883 + 654 WP_002911396.1 protein-serine/threonine phosphatase -
H224_RS09540 1915880..1916071 - 192 WP_002911395.1 YebW family protein -
H224_RS09545 1916169..1916408 - 240 WP_002911393.1 YebV family protein -
H224_RS09550 1916524..1917957 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T55369 NZ_CP011985:1913380-1913482 [Klebsiella pneumoniae UHKPC07]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT55369 NZ_CP011985:c1913489-1913344 [Klebsiella pneumoniae UHKPC07]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References