Detailed information of TA system TA055310

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-RelB
• Location: 2117..2630
• Replicon: chromosome
• Accession: NZ_CP011975
• Organism: Yersinia aleksiciae strain 159

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: ACZ76_RS00020
• Protein ID: WP_048615643.1
• Coordinates: 2346..2630 (+)
• Length: 95 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A386HFF3
• Locus tag: ACZ76_RS00015
• Protein ID: WP_012105237.1
• Coordinates: 2117..2356 (+)
• Length: 80 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ACZ76_RS00010	347..1990	-	1644	WP_048615641.1	phage terminase large subunit	-
ACZ76_RS00015	2117..2356	+	240	WP_012105237.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
ACZ76_RS00020	2346..2630	+	285	WP_048615643.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
ACZ76_RS00025	2641..3657	-	1017	WP_048615646.1	terminase small subunit	-
ACZ76_RS00030	3739..4182	+	444	WP_048615648.1	hypothetical protein	-
ACZ76_RS00035	4384..4638	-	255	WP_025378495.1	hypothetical protein	-
ACZ76_RS00040	4641..5255	-	615	WP_048615652.1	hypothetical protein	-
ACZ76_RS00045	5252..5761	-	510	WP_074007556.1	ParB/Srx family N-terminal domain-containing protein	-
ACZ76_RS00050	6065..6631	-	567	WP_048615654.1	hypothetical protein	-
ACZ76_RS00055	7017..7349	-	333	WP_048615656.1	DUF2570 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	347..29666	29319

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-81)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (2-76)

Sequences

Toxin

Protein

• Length: 95 a.a.
• Molecular weight: 11215.00 Da
• Isoelectric Point: 10.3315

>T55310 WP_048615643.1 NZ_CP011975:2346-2630 [Yersinia aleksiciae]
MTYNLDFDRRALKEWHKLGDTVRQQFKKKLLEVIKNPRVEANRLRDLPDCYKIKLRSAGYRLIYQVQDEKITVFVVAVGK
RDREEAYSEAGKRV

Nucleotide

• Length: 285 bp

>T55310 NZ_CP011975:2346-2630 [Yersinia aleksiciae]
ATGACTTATAATCTTGATTTTGATCGCCGGGCGCTAAAGGAATGGCATAAGCTCGGCGATACCGTACGCCAGCAATTTAA
GAAAAAGCTGCTCGAAGTGATTAAAAATCCACGCGTTGAAGCCAATAGACTGCGCGACTTACCTGATTGTTACAAAATAA
AACTACGCAGCGCCGGATACCGCCTGATTTATCAGGTGCAAGACGAAAAAATCACGGTTTTTGTGGTTGCCGTAGGTAAA
CGGGATCGTGAAGAAGCCTACAGTGAAGCTGGCAAGCGCGTCTGA

Antitoxin

Protein

• Length: 80 a.a.
• Molecular weight: 8836.12 Da
• Isoelectric Point: 4.5105

>AT55310 WP_012105237.1 NZ_CP011975:2117-2356 [Yersinia aleksiciae]
MGNINIRIDDDLKDRSYAVLEKLGVTPSDLLRQTLEYVAQSGKLPFKSVLLTDEDQALVAVVRERLANPQPVRVSLDDL

Nucleotide

• Length: 240 bp

>AT55310 NZ_CP011975:2117-2356 [Yersinia aleksiciae]
ATGGGTAACATTAATATTCGCATTGATGATGACTTAAAAGATCGTTCTTATGCGGTACTGGAAAAACTGGGGGTCACCCC
CTCTGATTTGCTACGCCAGACACTGGAATATGTGGCACAAAGTGGCAAACTGCCCTTTAAATCCGTGTTGCTGACCGATG
AAGATCAAGCACTGGTCGCCGTAGTCAGAGAACGTTTAGCCAATCCACAACCAGTCAGGGTATCACTGGATGACTTATAA