Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | vapBC/VapC-VagC |
Location | 5179719..5180353 | Replicon | chromosome |
Accession | NZ_CP011972 | ||
Organism | Pseudomonas syringae pv. actinidiae ICMP 18884 |
Toxin (Protein)
Gene name | vapC | Uniprot ID | - |
Locus tag | IYO_RS23305 | Protein ID | WP_003380365.1 |
Coordinates | 5179949..5180353 (+) | Length | 135 a.a. |
Antitoxin (Protein)
Gene name | vapB | Uniprot ID | Q888H8 |
Locus tag | IYO_RS23300 | Protein ID | WP_003380366.1 |
Coordinates | 5179719..5179949 (+) | Length | 77 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
IYO_RS23275 | 5174783..5175822 | + | 1040 | Protein_4565 | TRAP transporter substrate-binding protein | - |
IYO_RS23280 | 5175886..5176413 | + | 528 | WP_003380373.1 | TRAP transporter small permease | - |
IYO_RS23285 | 5176414..5177694 | + | 1281 | WP_003380372.1 | TRAP transporter large permease | - |
IYO_RS23290 | 5177778..5178748 | + | 971 | Protein_4568 | DMT family transporter | - |
IYO_RS23295 | 5178723..5179604 | + | 882 | WP_003380368.1 | aldose 1-epimerase | - |
IYO_RS23300 | 5179719..5179949 | + | 231 | WP_003380366.1 | antitoxin | Antitoxin |
IYO_RS23305 | 5179949..5180353 | + | 405 | WP_003380365.1 | tRNA(fMet)-specific endonuclease VapC | Toxin |
IYO_RS32290 | 5180540..5181115 | - | 576 | WP_019334082.1 | hypothetical protein | - |
IYO_RS23310 | 5181114..5181302 | + | 189 | WP_003380363.1 | hypothetical protein | - |
IYO_RS23315 | 5181538..5182050 | + | 513 | WP_003380362.1 | sigma-70 family RNA polymerase sigma factor | - |
IYO_RS23320 | 5182050..5182712 | + | 663 | WP_003380361.1 | ChrR family anti-sigma-E factor | - |
IYO_RS23325 | 5182788..5183024 | - | 237 | WP_003380360.1 | hypothetical protein | - |
IYO_RS23330 | 5183089..5184345 | - | 1257 | WP_003380359.1 | 3-phosphoshikimate 1-carboxyvinyltransferase | - |
IYO_RS23335 | 5184441..5184923 | - | 483 | WP_003380358.1 | PAS domain-containing protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 135 a.a. Molecular weight: 14814.09 Da Isoelectric Point: 6.8615
>T55306 WP_003380365.1 NZ_CP011972:5179949-5180353 [Pseudomonas syringae pv. actinidiae ICMP 18884]
MLKYMLDTNICIFTIKNKPVSVREAFNLHHGQLCISAITLMELVYGAEKSSSPERNLAVVEGFAARLELLPYDSAAAAHT
GMIRAELARAGTPIGPYDQMIAGHARSLGLVVITNNQREFQRVEGLRVEDWVSQ
MLKYMLDTNICIFTIKNKPVSVREAFNLHHGQLCISAITLMELVYGAEKSSSPERNLAVVEGFAARLELLPYDSAAAAHT
GMIRAELARAGTPIGPYDQMIAGHARSLGLVVITNNQREFQRVEGLRVEDWVSQ
Download Length: 405 bp
>T55306 NZ_CP011972:5179949-5180353 [Pseudomonas syringae pv. actinidiae ICMP 18884]
ATGCTCAAATACATGCTCGACACCAATATTTGCATCTTCACTATCAAGAACAAGCCGGTGTCGGTACGTGAGGCCTTCAA
CCTTCATCACGGGCAGCTGTGTATCAGCGCGATCACGTTGATGGAGCTTGTTTACGGCGCAGAAAAGTCTTCCAGTCCCG
AAAGAAATCTTGCTGTTGTAGAAGGTTTTGCAGCGCGTCTTGAATTGCTTCCCTACGATAGCGCCGCCGCGGCTCACACC
GGCATGATCAGAGCCGAGCTGGCCAGAGCGGGTACACCGATTGGCCCGTACGATCAAATGATTGCAGGACATGCCCGCTC
TCTTGGCCTCGTGGTCATCACCAACAACCAGCGTGAATTCCAGCGCGTCGAGGGGCTGAGGGTAGAAGACTGGGTAAGCC
AATAA
ATGCTCAAATACATGCTCGACACCAATATTTGCATCTTCACTATCAAGAACAAGCCGGTGTCGGTACGTGAGGCCTTCAA
CCTTCATCACGGGCAGCTGTGTATCAGCGCGATCACGTTGATGGAGCTTGTTTACGGCGCAGAAAAGTCTTCCAGTCCCG
AAAGAAATCTTGCTGTTGTAGAAGGTTTTGCAGCGCGTCTTGAATTGCTTCCCTACGATAGCGCCGCCGCGGCTCACACC
GGCATGATCAGAGCCGAGCTGGCCAGAGCGGGTACACCGATTGGCCCGTACGATCAAATGATTGCAGGACATGCCCGCTC
TCTTGGCCTCGTGGTCATCACCAACAACCAGCGTGAATTCCAGCGCGTCGAGGGGCTGAGGGTAGAAGACTGGGTAAGCC
AATAA
Antitoxin
Download Length: 77 a.a. Molecular weight: 8593.67 Da Isoelectric Point: 4.5557
>AT55306 WP_003380366.1 NZ_CP011972:5179719-5179949 [Pseudomonas syringae pv. actinidiae ICMP 18884]
MEQSTVFKSNRSQAVRLPKAVALPDDVKRVDVVAVGRTRIISPAGEMWNSWFDGESVSDDFMAEREQPVEQLRESL
MEQSTVFKSNRSQAVRLPKAVALPDDVKRVDVVAVGRTRIISPAGEMWNSWFDGESVSDDFMAEREQPVEQLRESL
Download Length: 231 bp
>AT55306 NZ_CP011972:5179719-5179949 [Pseudomonas syringae pv. actinidiae ICMP 18884]
ATGGAACAATCCACAGTCTTCAAAAGCAATCGAAGTCAGGCTGTTCGACTCCCAAAAGCGGTGGCATTACCCGACGACGT
GAAACGGGTAGACGTCGTAGCAGTGGGCAGGACACGCATCATTTCCCCTGCTGGTGAAATGTGGAACAGTTGGTTCGATG
GTGAAAGTGTCAGTGATGACTTCATGGCAGAGCGCGAGCAGCCAGTTGAACAGCTGCGCGAATCACTCTGA
ATGGAACAATCCACAGTCTTCAAAAGCAATCGAAGTCAGGCTGTTCGACTCCCAAAAGCGGTGGCATTACCCGACGACGT
GAAACGGGTAGACGTCGTAGCAGTGGGCAGGACACGCATCATTTCCCCTGCTGGTGAAATGTGGAACAGTTGGTTCGATG
GTGAAAGTGTCAGTGATGACTTCATGGCAGAGCGCGAGCAGCCAGTTGAACAGCTGCGCGAATCACTCTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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