55266

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) EcnAB/-
Location 4626096..4626457 Replicon chromosome
Accession NZ_CP011959
Organism Xanthomonas oryzae pv. oryzicola strain CFBP7341

Toxin (Protein)


Gene name EcnB Uniprot ID G7TLC7
Locus tag ACU17_RS20260 Protein ID WP_011257368.1
Coordinates 4626323..4626457 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID G7TLC8
Locus tag ACU17_RS20255 Protein ID WP_011407410.1
Coordinates 4626096..4626248 (+) Length 51 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ACU17_RS20225 4622437..4623120 - 684 WP_014505034.1 dTMP kinase -
ACU17_RS20230 4623600..4623892 - 293 Protein_3987 hypothetical protein -
ACU17_RS20235 4623902..4624137 - 236 Protein_3988 GTPase -
ACU17_RS20240 4624134..4624607 - 474 WP_033005008.1 hypothetical protein -
ACU17_RS20250 4625065..4625988 + 924 WP_014505030.1 arginase -
ACU17_RS20255 4626096..4626248 + 153 WP_011407410.1 entericidin A/B family lipoprotein Antitoxin
ACU17_RS20260 4626323..4626457 + 135 WP_011257368.1 entericidin A/B family lipoprotein Toxin
ACU17_RS20265 4626701..4626910 + 210 WP_011407411.1 CsbD family protein -
ACU17_RS20270 4627079..4628368 + 1290 WP_024711517.1 tryptophan--tRNA ligase -
ACU17_RS20275 4628421..4629443 + 1023 WP_179210401.1 MBL fold metallo-hydrolase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(23-42)

Antitoxin

(23-42)


Sequences


Toxin        


Download         Length: 45 a.a.        Molecular weight: 4457.33 Da        Isoelectric Point: 10.2040

>T55266 WP_011257368.1 NZ_CP011959:4626323-4626457 [Xanthomonas oryzae pv. oryzicola]
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T55266 NZ_CP011959:4626323-4626457 [Xanthomonas oryzae pv. oryzicola]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCCATGTTGTCGGTCGGTCTGCTGTCGGGCTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGAAGGGCGCCGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5046.99 Da        Isoelectric Point: 8.7942

>AT55266 WP_011407410.1 NZ_CP011959:4626096-4626248 [Xanthomonas oryzae pv. oryzicola]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT55266 NZ_CP011959:4626096-4626248 [Xanthomonas oryzae pv. oryzicola]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCTGGCGC
TGGCAAGGACTTGCAGGGCGCGGGTGGGAAGGTCGAGAAAACGGCCGAAAAATGCAGCGATGGTAAGTGCTGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A0C5UG40


Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V759

References