Detailed information of TA system TA055265

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): pmenTA/darT(toxin)
• Location: 1017506..1019187
• Replicon: chromosome
• Accession: NZ_CP011959
• Organism: Xanthomonas oryzae pv. oryzicola strain CFBP7341

Toxin (Protein)

• Gene name: pmenT
• Uniprot ID: -
• Locus tag: ACU17_RS04440
• Protein ID: WP_033004610.1
• Coordinates: 1018573..1019187 (-)
• Length: 205 a.a.

Antitoxin (Protein)

• Gene name: pmenA
• Uniprot ID: A0A7U4SBT2
• Locus tag: ACU17_RS04435
• Protein ID: WP_024710584.1
• Coordinates: 1017506..1018576 (-)
• Length: 357 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ACU17_RS04415	1013381..1013707	-	327	WP_024710580.1	hypothetical protein	-
ACU17_RS04420	1014011..1015291	-	1281	WP_024710581.1	amidohydrolase family protein	-
ACU17_RS04425	1015288..1016697	-	1410	WP_024710582.1	amidohydrolase	-
ACU17_RS04430	1016837..1017397	+	561	WP_024710583.1	DUF924 family protein	-
ACU17_RS04435	1017506..1018576	-	1071	WP_024710584.1	macro domain-containing protein	Antitoxin
ACU17_RS04440	1018573..1019187	-	615	WP_033004610.1	DUF4433 domain-containing protein	Toxin
ACU17_RS04445	1019557..1020483	-	927	WP_024710586.1	Grx4 family monothiol glutaredoxin	-
ACU17_RS04450	1020529..1021320	+	792	WP_024710587.1	polysaccharide deacetylase family protein	-
ACU17_RS04455	1021624..1022295	-	672	WP_024710588.1	class I SAM-dependent methyltransferase	-
ACU17_RS04460	1022618..1023268	-	651	WP_024710589.1	SGNH/GDSL hydrolase family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• ssDNA thymidine ADP-ribosyltransferase, DarT (3-203)

Antitoxin

• Macro domain (18-129)

Sequences

Toxin

Protein

• Length: 205 a.a.
• Molecular weight: 23758.99 Da
• Isoelectric Point: 7.5676

>T55265 WP_033004610.1 NZ_CP011959:c1019187-1018573 [Xanthomonas oryzae pv. oryzicola]
MIWRITHRGNLPWILDNGLHCGNAAVQSSSWVSISNPELIDKRSSHPVPLPPGGFSNDYVPFYFTPFLPMLRNIHTAWGG
IQRRPNEDIVILVSSLHHVAERRWPFLFTDSHAYCQLASFYSDLSDLDKIDWPLLQARDFRRDPDDPAKFERYQAEALIH
RHLPLDGLRGIVCHTDGLQQTIERQLQERNLKLPVHTRTGWYFR

Nucleotide

• Length: 615 bp

>T55265 NZ_CP011959:c1019187-1018573 [Xanthomonas oryzae pv. oryzicola]
CTGATCTGGCGCATCACCCACCGGGGCAATCTGCCGTGGATTCTGGACAACGGTCTGCACTGTGGTAATGCCGCTGTGCA
GAGTTCGAGTTGGGTGAGCATCAGCAACCCAGAACTGATCGACAAGCGCTCCAGTCATCCTGTACCGCTTCCACCGGGCG
GCTTCTCAAACGATTACGTGCCGTTCTACTTCACTCCGTTTTTGCCGATGCTGCGCAACATCCATACCGCCTGGGGTGGA
ATCCAAAGGCGGCCTAACGAAGACATCGTCATCCTTGTTTCCAGCTTGCATCATGTCGCCGAACGCCGATGGCCGTTTCT
GTTTACTGACAGCCACGCCTACTGCCAGTTGGCGAGCTTCTATTCCGATTTATCCGATCTCGACAAGATCGACTGGCCGT
TGCTCCAAGCACGCGATTTCCGGCGCGACCCAGACGACCCAGCCAAGTTCGAGCGCTATCAGGCCGAGGCCCTGATTCAC
CGACACTTGCCGCTTGATGGCCTGCGCGGCATTGTGTGTCATACGGATGGTTTGCAACAGACCATCGAGCGGCAACTCCA
AGAGCGAAACCTGAAATTGCCGGTTCATACCCGCACCGGGTGGTATTTCCGATGA

Antitoxin

Protein

• Length: 357 a.a.
• Molecular weight: 39912.93 Da
• Isoelectric Point: 6.2639

>AT55265 WP_024710584.1 NZ_CP011959:c1018576-1017506 [Xanthomonas oryzae pv. oryzicola]
MITFTQGNLLESGAEALVNTVNTVGVMGKGIALMFKERFKENFLRYAAACKDNQVRIGKIFVTEVNELDGPRWIINFPTK
QHWRGDSRIEWITEGLQDLHRFLIENKVKSIAIPPLGAGNGGLDRADVRPLIEEVLAGLDTDILVFEPTLKYQNVAKRSG
VEKLTPARALIAELVRRYWVLGMECGLLEIQKLAWFLERNIERAGLPELDLRFSAHKYGPYADRLRHLLNGLDGSYLHCD
KRISDADPLDVIWFDDNRKSFVQTYLKSEAKQYIPALEATAALIDGFESPFGMELLATVDWLIVQEGISAQVADVREGIR
HWPGGQEAAARKDRLFDDRALGIALKRLASGAIAVA

Nucleotide

• Length: 1071 bp

>AT55265 NZ_CP011959:c1018576-1017506 [Xanthomonas oryzae pv. oryzicola]
ATGATCACGTTCACACAAGGCAATCTACTGGAGTCTGGCGCAGAGGCGCTGGTCAACACCGTCAACACCGTCGGCGTGAT
GGGCAAGGGCATCGCGCTGATGTTCAAGGAGCGCTTCAAGGAGAACTTCCTCCGATATGCCGCCGCCTGCAAAGACAACC
AAGTGCGCATTGGCAAAATTTTCGTCACCGAAGTCAACGAACTGGACGGGCCACGCTGGATCATCAATTTTCCGACCAAA
CAGCACTGGCGTGGCGATTCCCGCATCGAATGGATCACTGAAGGATTGCAGGACTTGCACCGTTTTCTGATCGAGAACAA
AGTCAAATCCATTGCCATCCCGCCACTGGGCGCGGGCAATGGAGGATTGGACCGGGCCGACGTGCGCCCACTGATCGAAG
AAGTACTAGCAGGTTTGGATACAGACATCCTCGTGTTCGAGCCTACCTTGAAGTATCAGAACGTTGCCAAGCGCTCCGGC
GTGGAAAAATTGACCCCGGCACGCGCCTTGATTGCCGAGCTGGTACGTCGTTACTGGGTGCTAGGTATGGAATGCGGCCT
GTTGGAAATCCAGAAACTGGCGTGGTTCCTTGAACGCAACATCGAGCGAGCGGGCTTGCCTGAGCTTGATTTGCGCTTTT
CAGCACACAAGTACGGCCCTTATGCCGACCGTCTACGCCATCTTCTGAACGGGCTGGACGGAAGCTACCTGCATTGTGAC
AAACGGATCAGCGACGCCGACCCGCTGGACGTGATCTGGTTCGACGACAATCGCAAAAGCTTCGTACAGACCTACCTAAA
GAGCGAGGCGAAACAGTACATTCCAGCACTGGAAGCTACTGCCGCCTTGATCGATGGTTTTGAATCTCCTTTTGGCATGG
AGTTGTTGGCGACAGTTGACTGGCTGATTGTGCAGGAAGGTATCTCTGCGCAAGTTGCCGACGTGCGTGAAGGCATACGC
CACTGGCCAGGTGGTCAGGAGGCAGCGGCGCGAAAGGACAGACTGTTCGATGACCGCGCCTTGGGGATCGCGCTGAAACG
ACTGGCATCAGGTGCAATCGCAGTGGCTTAA

Structures

Antitoxin

• AlphaFold DB: A0A7U4SBT2