Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4616410..4616771 Replicon chromosome
Accession NZ_CP011958
Organism Xanthomonas oryzae pv. oryzicola strain CFBP7331

Toxin (Protein)


Gene name EcnB Uniprot ID G7TLC7
Locus tag ACU16_RS20250 Protein ID WP_011257368.1
Coordinates 4616637..4616771 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID G7TLC8
Locus tag ACU16_RS20245 Protein ID WP_011407410.1
Coordinates 4616410..4616562 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ACU16_RS20215 4612751..4613434 - 684 WP_014505034.1 dTMP kinase -
ACU16_RS20220 4613914..4614206 - 293 Protein_3973 hypothetical protein -
ACU16_RS20225 4614216..4614451 - 236 Protein_3974 GTPase -
ACU16_RS20230 4614448..4614921 - 474 WP_033005008.1 hypothetical protein -
ACU16_RS20240 4615379..4616302 + 924 WP_014505030.1 arginase -
ACU16_RS20245 4616410..4616562 + 153 WP_011407410.1 entericidin A/B family lipoprotein Antitoxin
ACU16_RS20250 4616637..4616771 + 135 WP_011257368.1 entericidin A/B family lipoprotein Toxin
ACU16_RS20255 4617015..4617224 + 210 WP_011407411.1 CsbD family protein -
ACU16_RS20260 4617393..4618682 + 1290 WP_024711517.1 tryptophan--tRNA ligase -
ACU16_RS20265 4618735..4619757 + 1023 WP_192820313.1 MBL fold metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4457.33 Da        Isoelectric Point: 10.2040

>T55263 WP_011257368.1 NZ_CP011958:4616637-4616771 [Xanthomonas oryzae pv. oryzicola]
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T55263 NZ_CP011958:4616637-4616771 [Xanthomonas oryzae pv. oryzicola]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCCATGTTGTCGGTCGGTCTGCTGTCGGGCTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGAAGGGCGCCGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5046.99 Da        Isoelectric Point: 8.7942

>AT55263 WP_011407410.1 NZ_CP011958:4616410-4616562 [Xanthomonas oryzae pv. oryzicola]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT55263 NZ_CP011958:4616410-4616562 [Xanthomonas oryzae pv. oryzicola]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCTGGCGC
TGGCAAGGACTTGCAGGGCGCGGGTGGGAAGGTCGAGAAAACGGCCGAAAAATGCAGCGATGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0C5UG40

Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V759

References