Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 1056081..1057762 Replicon chromosome
Accession NZ_CP011958
Organism Xanthomonas oryzae pv. oryzicola strain CFBP7331

Toxin (Protein)


Gene name pmenT Uniprot ID -
Locus tag ACU16_RS04595 Protein ID WP_033004610.1
Coordinates 1057148..1057762 (-) Length 205 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID A0A7U4SBT2
Locus tag ACU16_RS04590 Protein ID WP_024710584.1
Coordinates 1056081..1057151 (-) Length 357 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ACU16_RS04570 1051956..1052282 - 327 WP_024710580.1 hypothetical protein -
ACU16_RS04575 1052586..1053866 - 1281 WP_024710581.1 amidohydrolase family protein -
ACU16_RS04580 1053863..1055272 - 1410 WP_024710582.1 amidohydrolase -
ACU16_RS04585 1055412..1055972 + 561 WP_024710583.1 DUF924 family protein -
ACU16_RS04590 1056081..1057151 - 1071 WP_024710584.1 macro domain-containing protein Antitoxin
ACU16_RS04595 1057148..1057762 - 615 WP_033004610.1 DUF4433 domain-containing protein Toxin
ACU16_RS04600 1058132..1059058 - 927 WP_024710586.1 Grx4 family monothiol glutaredoxin -
ACU16_RS04605 1059104..1059895 + 792 WP_024710587.1 polysaccharide deacetylase family protein -
ACU16_RS04610 1060199..1060870 - 672 WP_024710588.1 class I SAM-dependent methyltransferase -
ACU16_RS04615 1061193..1061843 - 651 WP_024710589.1 SGNH/GDSL hydrolase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

ssDNA thymidine ADP-ribosyltransferase, DarT

(3-203)

Antitoxin

Macro domain

(18-129)


Sequences

Toxin        


Download         Length: 205 a.a.        Molecular weight: 23758.99 Da        Isoelectric Point: 7.5676

>T55262 WP_033004610.1 NZ_CP011958:c1057762-1057148 [Xanthomonas oryzae pv. oryzicola]
MIWRITHRGNLPWILDNGLHCGNAAVQSSSWVSISNPELIDKRSSHPVPLPPGGFSNDYVPFYFTPFLPMLRNIHTAWGG
IQRRPNEDIVILVSSLHHVAERRWPFLFTDSHAYCQLASFYSDLSDLDKIDWPLLQARDFRRDPDDPAKFERYQAEALIH
RHLPLDGLRGIVCHTDGLQQTIERQLQERNLKLPVHTRTGWYFR

Download         Length: 615 bp

>T55262 NZ_CP011958:c1057762-1057148 [Xanthomonas oryzae pv. oryzicola]
CTGATCTGGCGCATCACCCACCGGGGCAATCTGCCGTGGATTCTGGACAACGGTCTGCACTGTGGTAATGCCGCTGTGCA
GAGTTCGAGTTGGGTGAGCATCAGCAACCCAGAACTGATCGACAAGCGCTCCAGTCATCCTGTACCGCTTCCACCGGGCG
GCTTCTCAAACGATTACGTGCCGTTCTACTTCACTCCGTTTTTGCCGATGCTGCGCAACATCCATACCGCCTGGGGTGGA
ATCCAAAGGCGGCCTAACGAAGACATCGTCATCCTTGTTTCCAGCTTGCATCATGTCGCCGAACGCCGATGGCCGTTTCT
GTTTACTGACAGCCACGCCTACTGCCAGTTGGCGAGCTTCTATTCCGATTTATCCGATCTCGACAAGATCGACTGGCCGT
TGCTCCAAGCACGCGATTTCCGGCGCGACCCAGACGACCCAGCCAAGTTCGAGCGCTATCAGGCCGAGGCCCTGATTCAC
CGACACTTGCCGCTTGATGGCCTGCGCGGCATTGTGTGTCATACGGATGGTTTGCAACAGACCATCGAGCGGCAACTCCA
AGAGCGAAACCTGAAATTGCCGGTTCATACCCGCACCGGGTGGTATTTCCGATGA

Antitoxin


Download         Length: 357 a.a.        Molecular weight: 39912.93 Da        Isoelectric Point: 6.2639

>AT55262 WP_024710584.1 NZ_CP011958:c1057151-1056081 [Xanthomonas oryzae pv. oryzicola]
MITFTQGNLLESGAEALVNTVNTVGVMGKGIALMFKERFKENFLRYAAACKDNQVRIGKIFVTEVNELDGPRWIINFPTK
QHWRGDSRIEWITEGLQDLHRFLIENKVKSIAIPPLGAGNGGLDRADVRPLIEEVLAGLDTDILVFEPTLKYQNVAKRSG
VEKLTPARALIAELVRRYWVLGMECGLLEIQKLAWFLERNIERAGLPELDLRFSAHKYGPYADRLRHLLNGLDGSYLHCD
KRISDADPLDVIWFDDNRKSFVQTYLKSEAKQYIPALEATAALIDGFESPFGMELLATVDWLIVQEGISAQVADVREGIR
HWPGGQEAAARKDRLFDDRALGIALKRLASGAIAVA

Download         Length: 1071 bp

>AT55262 NZ_CP011958:c1057151-1056081 [Xanthomonas oryzae pv. oryzicola]
ATGATCACGTTCACACAAGGCAATCTACTGGAGTCTGGCGCAGAGGCGCTGGTCAACACCGTCAACACCGTCGGCGTGAT
GGGCAAGGGCATCGCGCTGATGTTCAAGGAGCGCTTCAAGGAGAACTTCCTCCGATATGCCGCCGCCTGCAAAGACAACC
AAGTGCGCATTGGCAAAATTTTCGTCACCGAAGTCAACGAACTGGACGGGCCACGCTGGATCATCAATTTTCCGACCAAA
CAGCACTGGCGTGGCGATTCCCGCATCGAATGGATCACTGAAGGATTGCAGGACTTGCACCGTTTTCTGATCGAGAACAA
AGTCAAATCCATTGCCATCCCGCCACTGGGCGCGGGCAATGGAGGATTGGACCGGGCCGACGTGCGCCCACTGATCGAAG
AAGTACTAGCAGGTTTGGATACAGACATCCTCGTGTTCGAGCCTACCTTGAAGTATCAGAACGTTGCCAAGCGCTCCGGC
GTGGAAAAATTGACCCCGGCACGCGCCTTGATTGCCGAGCTGGTACGTCGTTACTGGGTGCTAGGTATGGAATGCGGCCT
GTTGGAAATCCAGAAACTGGCGTGGTTCCTTGAACGCAACATCGAGCGAGCGGGCTTGCCTGAGCTTGATTTGCGCTTTT
CAGCACACAAGTACGGCCCTTATGCCGACCGTCTACGCCATCTTCTGAACGGGCTGGACGGAAGCTACCTGCATTGTGAC
AAACGGATCAGCGACGCCGACCCGCTGGACGTGATCTGGTTCGACGACAATCGCAAAAGCTTCGTACAGACCTACCTAAA
GAGCGAGGCGAAACAGTACATTCCAGCACTGGAAGCTACTGCCGCCTTGATCGATGGTTTTGAATCTCCTTTTGGCATGG
AGTTGTTGGCGACAGTTGACTGGCTGATTGTGCAGGAAGGTATCTCTGCGCAAGTTGCCGACGTGCGTGAAGGCATACGC
CACTGGCCAGGTGGTCAGGAGGCAGCGGCGCGAAAGGACAGACTGTTCGATGACCGCGCCTTGGGGATCGCGCTGAAACG
ACTGGCATCAGGTGCAATCGCAGTGGCTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7U4SBT2

References