Detailed information of TA system TA055258

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): pmenTA/darT(toxin)
• Location: 907396..909077
• Replicon: chromosome
• Accession: NZ_CP011957
• Organism: Xanthomonas oryzae pv. oryzicola strain BXOR1

Toxin (Protein)

• Gene name: pmenT
• Uniprot ID: -
• Locus tag: ACU15_RS03990
• Protein ID: WP_047340151.1
• Coordinates: 908463..909077 (-)
• Length: 205 a.a.

Antitoxin (Protein)

• Gene name: pmenA
• Uniprot ID: A0A5E8KSB4
• Locus tag: ACU15_RS03985
• Protein ID: WP_047340152.1
• Coordinates: 907396..908466 (-)
• Length: 357 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ACU15_RS03965	903271..903597	-	327	WP_041183782.1	hypothetical protein	-
ACU15_RS03970	903901..905181	-	1281	WP_048485358.1	amidohydrolase family protein	-
ACU15_RS03975	905178..906587	-	1410	WP_047340153.1	amidohydrolase	-
ACU15_RS03980	906727..907287	+	561	WP_044750878.1	DUF924 family protein	-
ACU15_RS03985	907396..908466	-	1071	WP_047340152.1	macro domain-containing protein	Antitoxin
ACU15_RS03990	908463..909077	-	615	WP_047340151.1	DUF4433 domain-containing protein	Toxin
ACU15_RS03995	909447..910373	-	927	WP_024710586.1	Grx4 family monothiol glutaredoxin	-
ACU15_RS04000	910419..911210	+	792	WP_024710587.1	polysaccharide deacetylase family protein	-
ACU15_RS04005	911514..912185	-	672	WP_047340150.1	class I SAM-dependent methyltransferase	-
ACU15_RS04010	912508..913158	-	651	WP_024710589.1	SGNH/GDSL hydrolase family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• ssDNA thymidine ADP-ribosyltransferase, DarT (3-203)

Antitoxin

• Macro domain (18-129)

Sequences

Toxin

Protein

• Length: 205 a.a.
• Molecular weight: 23714.94 Da
• Isoelectric Point: 7.5676

>T55258 WP_047340151.1 NZ_CP011957:c909077-908463 [Xanthomonas oryzae pv. oryzicola]
MIWRITHRGNLPWILDNGLHCGNAAVQSSSWVSIGNPELIDKRSSHPVPLPPGGFSNDYVPFYFTPFLPMLRNIHTAWGG
IQRRPNEDIVILVSSLHHVAERRWPFLFTDSHAYCQLASFYSDLSDLDKIDWPLLQARDFRRDPDDPAKFERYQAEALIH
RHVPLDGLRGIVCHTDGLQQTIERQLQERNLKLPVHTRTGWYFR

Nucleotide

• Length: 615 bp

>T55258 NZ_CP011957:c909077-908463 [Xanthomonas oryzae pv. oryzicola]
CTGATCTGGCGCATCACCCACCGGGGCAATCTGCCGTGGATTCTGGACAACGGTCTGCACTGTGGTAATGCCGCTGTGCA
GAGTTCGAGTTGGGTGAGCATCGGCAACCCAGAACTGATCGACAAGCGCTCCAGTCATCCTGTACCGCTTCCACCGGGCG
GCTTCTCAAACGATTACGTGCCGTTCTACTTCACTCCGTTTTTGCCGATGCTGCGCAACATCCATACCGCCTGGGGTGGA
ATCCAAAGGCGGCCTAACGAAGACATCGTCATCCTTGTTTCCAGCTTGCATCATGTCGCCGAACGCCGATGGCCGTTTCT
GTTTACTGACAGCCACGCCTACTGCCAGTTGGCGAGCTTCTATTCCGATTTATCCGATCTCGACAAGATCGACTGGCCGT
TGCTCCAAGCACGCGATTTCCGGCGCGACCCAGACGACCCAGCCAAGTTCGAGCGCTATCAGGCCGAGGCCCTGATTCAC
CGACACGTGCCGCTTGATGGCCTGCGCGGCATTGTGTGTCATACGGATGGTTTGCAACAGACCATCGAGCGGCAACTCCA
AGAGCGAAACCTGAAATTGCCGGTTCATACCCGCACCGGGTGGTATTTCCGATGA

Antitoxin

Protein

• Length: 357 a.a.
• Molecular weight: 39970.97 Da
• Isoelectric Point: 6.0089

>AT55258 WP_047340152.1 NZ_CP011957:c908466-907396 [Xanthomonas oryzae pv. oryzicola]
MITFTQGNLLESGAEALVNTVNTVGVMGKGIALMFKERFKENFLRYAAACKDNQVRIGKIFVTEVNELDGPRWIINFPTK
QHWRGDSRIEWITEGLQDLHRFLIENKVKSIAIPPLGAGNGGLDRADVRPLIEEVLAGLDTDILVFEPTLKYQNVAKRSG
VEKLTPARALIAELVRRYWVLGMECGLLEIQKLAWFLERNIERAGLPELDLRFSAHKYGPYADRLRHLLNGLDGSYLHCD
KRISDADPLDVIWFDDNRKSFVQTYLKSEAKQYIPALEATAALIDGFESPFGMELLATVDWLIVQEGISAQVADVREGIR
HWPGDQEAAARKDRLFDDRALGIALKRLASGAIAVA

Nucleotide

• Length: 1071 bp

>AT55258 NZ_CP011957:c908466-907396 [Xanthomonas oryzae pv. oryzicola]
ATGATCACGTTCACACAAGGCAATCTACTGGAGTCTGGCGCAGAGGCGCTGGTCAACACCGTCAACACCGTCGGCGTGAT
GGGCAAGGGCATCGCGCTGATGTTCAAGGAGCGCTTCAAGGAGAACTTCCTCCGATATGCCGCCGCCTGCAAAGACAACC
AAGTGCGCATTGGCAAAATTTTCGTCACCGAAGTCAACGAACTGGACGGGCCACGCTGGATCATCAATTTTCCGACCAAA
CAGCACTGGCGTGGCGATTCCCGCATCGAATGGATCACTGAAGGATTGCAGGACTTGCACCGTTTTCTGATCGAGAACAA
AGTCAAATCCATTGCCATCCCGCCACTGGGCGCGGGCAATGGAGGATTGGACCGGGCCGACGTGCGCCCACTGATCGAAG
AAGTACTAGCAGGTTTGGATACAGACATCCTCGTGTTCGAGCCTACCTTGAAGTATCAGAACGTTGCCAAGCGCTCCGGC
GTGGAAAAATTGACCCCGGCACGCGCCTTGATTGCCGAGCTGGTACGTCGTTACTGGGTGCTAGGTATGGAATGCGGCCT
GTTGGAAATCCAGAAACTGGCGTGGTTCCTTGAACGCAACATCGAGCGAGCGGGCTTGCCTGAGCTTGATTTGCGCTTTT
CAGCACACAAGTACGGCCCTTATGCCGACCGTCTACGCCATCTTCTGAACGGGCTGGACGGAAGCTACCTGCATTGTGAC
AAACGGATCAGCGACGCCGACCCGCTGGACGTGATCTGGTTCGACGACAATCGCAAAAGCTTCGTACAGACCTACCTAAA
GAGCGAGGCGAAACAGTACATTCCAGCACTGGAAGCTACTGCCGCCTTGATCGATGGTTTTGAATCTCCTTTTGGCATGG
AGTTGTTGGCGACAGTTGACTGGCTGATTGTGCAGGAAGGTATCTCTGCGCAAGTTGCCGACGTGCGTGAAGGCATACGC
CACTGGCCAGGTGATCAGGAGGCAGCGGCGCGAAAGGACAGACTGTTCGATGACCGCGCCTTGGGGATCGCGCTGAAACG
ACTGGCATCAGGTGCAATCGCAGTGGCTTAA

Structures

Antitoxin

• AlphaFold DB: A0A5E8KSB4