Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) EcnAB/-
Location 398711..399072 Replicon chromosome
Accession NZ_CP011955
Organism Xanthomonas oryzae pv. oryzicola strain B8-12

Toxin (Protein)


Gene name EcnB Uniprot ID G7TLC7
Locus tag ACU13_RS01715 Protein ID WP_011257368.1
Coordinates 398938..399072 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID G7TLC8
Locus tag ACU13_RS01710 Protein ID WP_011407410.1
Coordinates 398711..398863 (+) Length 51 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ACU13_RS01690 395052..395735 - 684 WP_014505034.1 dTMP kinase -
ACU13_RS01695 396215..396753 - 539 Protein_326 GTPase -
ACU13_RS01700 396750..397358 - 609 WP_047340248.1 hypothetical protein -
ACU13_RS01705 397680..398603 + 924 WP_014505030.1 arginase -
ACU13_RS01710 398711..398863 + 153 WP_011407410.1 entericidin A/B family lipoprotein Antitoxin
ACU13_RS01715 398938..399072 + 135 WP_011257368.1 entericidin A/B family lipoprotein Toxin
ACU13_RS01720 399317..399526 + 210 WP_011407411.1 CsbD family protein -
ACU13_RS01725 399695..400984 + 1290 WP_048482945.1 tryptophan--tRNA ligase -
ACU13_RS01730 401037..402059 + 1023 WP_195765576.1 MBL fold metallo-hydrolase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(23-42)

Antitoxin

(23-42)


Sequences


Toxin        


Download         Length: 45 a.a.        Molecular weight: 4457.33 Da        Isoelectric Point: 10.2040

>T55250 WP_011257368.1 NZ_CP011955:398938-399072 [Xanthomonas oryzae pv. oryzicola]
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T55250 NZ_CP011955:398938-399072 [Xanthomonas oryzae pv. oryzicola]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCCATGTTGTCGGTCGGTCTGCTGTCGGGCTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGAAGGGCGCCGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5046.99 Da        Isoelectric Point: 8.7942

>AT55250 WP_011407410.1 NZ_CP011955:398711-398863 [Xanthomonas oryzae pv. oryzicola]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT55250 NZ_CP011955:398711-398863 [Xanthomonas oryzae pv. oryzicola]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCTGGCGC
TGGCAAGGACTTGCAGGGCGCGGGTGGGAAGGTCGAGAAAACGGCCGAAAAATGCAGCGATGGTAAGTGCTGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A0C5UG40


Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V759

References