Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 1148046..1148574 Replicon chromosome
Accession NZ_CP011929
Organism Marinobacter sp. CP1

Toxin (Protein)


Gene name relE Uniprot ID A0A0K1U7C4
Locus tag ACP86_RS05470 Protein ID WP_053112998.1
Coordinates 1148046..1148336 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A285Q521
Locus tag ACP86_RS05475 Protein ID WP_053112999.1
Coordinates 1148326..1148574 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ACP86_RS05445 1143401..1144468 + 1068 WP_008169303.1 A/G-specific adenine glycosylase -
ACP86_RS05450 1144544..1144816 + 273 WP_008169302.1 oxidative damage protection protein -
ACP86_RS05460 1145455..1146195 - 741 WP_053112996.1 IS21-like element helper ATPase IstB -
ACP86_RS05465 1146182..1147687 - 1506 WP_082220543.1 IS21 family transposase -
ACP86_RS05470 1148046..1148336 - 291 WP_053112998.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
ACP86_RS05475 1148326..1148574 - 249 WP_053112999.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
ACP86_RS05480 1149198..1149611 - 414 WP_053113000.1 hypothetical protein -
ACP86_RS05485 1149740..1150138 - 399 WP_053113001.1 GFA family protein -
ACP86_RS05490 1150256..1150918 - 663 Protein_1102 group II intron reverse transcriptase/maturase -
ACP86_RS05495 1151216..1152517 + 1302 WP_041336316.1 IS1380 family transposase -
ACP86_RS05500 1153169..1153519 - 351 WP_053113002.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside IScluster/Tn - - 1145455..1152517 7062


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(8-85)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10915.84 Da        Isoelectric Point: 10.4679

>T55207 WP_053112998.1 NZ_CP011929:c1148336-1148046 [Marinobacter sp. CP1]
MSFKYSLAFKPSALKEWKKLAPAIRDQFKKKLAKRLEEPHVLADALSGLQGCYKIKLKSVGYRLVYQVEDGDILVTVVAV
GRRERGDVYSKAKDRT

Download         Length: 291 bp

>T55207 NZ_CP011929:c1148336-1148046 [Marinobacter sp. CP1]
ATGAGCTTTAAGTATTCGCTTGCATTCAAACCATCAGCTCTCAAGGAATGGAAGAAGCTCGCTCCGGCAATTCGAGATCA
GTTTAAGAAGAAGTTAGCGAAACGCCTCGAAGAACCTCACGTTCTAGCTGACGCCCTGTCGGGGCTACAAGGTTGCTACA
AAATCAAATTAAAGAGTGTTGGATATCGTTTAGTCTACCAGGTTGAGGACGGTGATATTTTAGTGACCGTCGTAGCCGTG
GGGCGGCGGGAACGCGGCGATGTGTACAGCAAGGCGAAAGATCGAACGTGA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9197.56 Da        Isoelectric Point: 4.1819

>AT55207 WP_053112999.1 NZ_CP011929:c1148574-1148326 [Marinobacter sp. CP1]
VTNQIYSEVTASISELKKNPMAAVDSGEGFPIVVLNRNKPAFYCVPAEIYEAMLDRLDDQEMVAIVKERLVEPSIRVDLN
EL

Download         Length: 249 bp

>AT55207 NZ_CP011929:c1148574-1148326 [Marinobacter sp. CP1]
GTGACCAATCAAATTTATTCTGAAGTGACCGCGAGCATTTCAGAACTCAAAAAAAATCCGATGGCGGCCGTGGATTCAGG
AGAGGGGTTTCCGATCGTTGTTCTAAACCGCAACAAACCGGCGTTCTACTGCGTTCCGGCTGAAATCTACGAAGCCATGC
TTGACCGACTAGACGACCAAGAGATGGTGGCAATCGTGAAAGAGAGACTTGTAGAGCCAAGTATTCGAGTCGATCTGAAT
GAGCTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0K1U7C4

Antitoxin

Source ID Structure
AlphaFold DB A0A285Q521

References