Detailed information of TA system TA055206

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/LOTUS_5_Limkain_b1-Phd
• Location: 45389..46035
• Replicon: plasmid pBCL1
• Accession: NZ_CP011928
• Organism: Labrenzia sp. CP4

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: ACP90_RS27565
• Protein ID: WP_062492135.1
• Coordinates: 45628..46035 (+)
• Length: 136 a.a.

Antitoxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: ACP90_RS28110
• Protein ID: WP_082809967.1
• Coordinates: 45389..45631 (+)
• Length: 81 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ACP90_RS27550	41595..42789	+	1195	Protein_47	plasmid partitioning protein RepA	-
ACP90_RS27555	42793..43794	+	1002	WP_062492131.1	plasmid partitioning protein RepB	-
ACP90_RS27560	44018..45274	+	1257	WP_062492133.1	replication protein C	-
ACP90_RS28110	45389..45631	+	243	WP_082809967.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
ACP90_RS27565	45628..46035	+	408	WP_062492135.1	type II toxin-antitoxin system VapC family toxin	Toxin
ACP90_RS27570	46260..46466	+	207	WP_062492137.1	antitoxin VbhA family protein	-
ACP90_RS28115	46531..48249	+	1719	WP_082809968.1	Fic family protein	-
ACP90_RS27580	48525..48869	+	345	WP_062492226.1	DUF736 family protein	-
ACP90_RS27585	49174..49461	+	288	WP_062492139.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..98619	98619

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (3-118)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (2-50)

Sequences

Toxin

Protein

• Length: 136 a.a.
• Molecular weight: 15120.26 Da
• Isoelectric Point: 5.2058

>T55206 WP_062492135.1 NZ_CP011928:45628-46035 [Labrenzia sp. CP4]
MIYVLDTNVITAARRAERAPKVAAWLSDKPEETLYVSVVTLGEIERGIRLQERRNMDFAKHLRQWLDRTVSMFGDRLLEF
TASDALCWGELSARIGHNGADLMIAAQALTRNGWVVTGNASDFEPTGVQLVDPFV

Nucleotide

• Length: 408 bp

>T55206 NZ_CP011928:45628-46035 [Labrenzia sp. CP4]
TTGATCTATGTTCTGGATACAAACGTGATTACTGCCGCAAGGCGTGCGGAAAGAGCGCCCAAGGTCGCTGCCTGGTTGTC
GGATAAGCCGGAGGAAACGCTCTATGTGAGCGTTGTCACGCTTGGCGAAATTGAAAGAGGAATCCGGCTTCAGGAACGGC
GGAATATGGATTTTGCCAAGCATCTTCGTCAGTGGTTGGACCGGACGGTTTCAATGTTTGGAGACCGGTTGTTGGAGTTT
ACCGCATCAGATGCCTTATGTTGGGGTGAGCTCTCCGCGAGAATTGGTCACAACGGCGCTGATCTGATGATTGCTGCTCA
GGCTTTGACCCGTAACGGATGGGTCGTTACCGGGAACGCGTCTGATTTTGAACCGACAGGCGTGCAACTTGTCGATCCAT
TCGTTTGA

Antitoxin

Protein

• Length: 81 a.a.
• Molecular weight: 9002.25 Da
• Isoelectric Point: 10.4416

>AT55206 WP_082809967.1 NZ_CP011928:45389-45631 [Labrenzia sp. CP4]
MISLQDAKNRFSAVVEAAMAGRPQEVSRRGKPAVVVISSEEYRRLLREAKGRRESFADHVLSFPGEGIERSKVTPRDVEF

Nucleotide

• Length: 243 bp

>AT55206 NZ_CP011928:45389-45631 [Labrenzia sp. CP4]
ATGATTTCTCTTCAAGATGCAAAGAACAGATTCAGCGCTGTGGTTGAAGCCGCAATGGCTGGCCGGCCTCAGGAAGTGTC
CCGCAGAGGCAAACCAGCTGTCGTCGTTATTTCCTCGGAAGAGTATCGCCGGCTTCTCAGAGAAGCGAAGGGGCGGCGCG
AGAGCTTTGCAGACCATGTCCTCAGCTTCCCGGGAGAGGGCATTGAGCGATCAAAGGTAACGCCCCGGGATGTCGAATTT
TGA