Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/-
Location 3970984..3972223 Replicon chromosome
Accession NZ_CP011927
Organism Labrenzia sp. CP4

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag ACP90_RS18255 Protein ID WP_062491745.1
Coordinates 3971603..3972223 (+) Length 207 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag ACP90_RS18250 Protein ID WP_062489195.1
Coordinates 3970984..3971553 (+) Length 190 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ACP90_RS18230 3967033..3967881 - 849 WP_023000192.1 phosphonate ABC transporter, permease protein PhnE -
ACP90_RS18235 3968064..3968978 - 915 WP_023000193.1 phosphonate ABC transporter substrate-binding protein -
ACP90_RS18240 3969037..3969870 - 834 WP_055659582.1 phosphonate ABC transporter ATP-binding protein -
ACP90_RS18245 3970270..3970896 + 627 WP_055659209.1 chloramphenicol acetyltransferase -
ACP90_RS18250 3970984..3971553 + 570 WP_062489195.1 helix-turn-helix transcriptional regulator Antitoxin
ACP90_RS18255 3971603..3972223 + 621 WP_062491745.1 HD domain-containing protein Toxin
ACP90_RS18260 3972363..3972734 + 372 WP_023000198.1 STAS/SEC14 domain-containing protein -
ACP90_RS18265 3972833..3973621 - 789 WP_023000199.1 class II glutamine amidotransferase -
ACP90_RS18270 3973638..3975104 - 1467 WP_062489197.1 aminotransferase class V-fold PLP-dependent enzyme -
ACP90_RS18275 3975209..3975670 + 462 WP_023000201.1 Lrp/AsnC family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

5'-deoxynucleotidase YfbR/HDDC2

(19-156)

Antitoxin

Cro/C1-type helix-turn-helix domain

(16-68)


Sequences

Toxin        


Download         Length: 207 a.a.        Molecular weight: 23042.17 Da        Isoelectric Point: 4.6200

>T55205 WP_062491745.1 NZ_CP011927:3971603-3972223 [Labrenzia sp. CP4]
MTKTPPSLDLPEISHTRLTGLLDFLQAAEQLKDTLRSGSTSGGRPESTAEHSWRLALMVLLFEPELKEIDMLKLLKLTLV
HDLGEAISGDVPAPLQSPGDDRQERERRDFLTLCEPLPGDVAGELTSLWDEYAAARTSEARLAKAFDKLETMLQHVLMPR
QAPSFYEFNLGYGRDRTDCSALTRQLRDEVDELTRTMMTGAGREIA

Download         Length: 621 bp

>T55205 NZ_CP011927:3971603-3972223 [Labrenzia sp. CP4]
ATGACAAAGACGCCCCCTTCCCTCGATCTTCCTGAAATTTCCCACACCAGACTGACGGGCCTGCTGGACTTCCTTCAGGC
TGCAGAGCAGCTGAAGGACACGCTTCGCTCGGGTTCGACATCCGGCGGCAGGCCGGAGAGCACTGCCGAACATAGCTGGC
GACTAGCCTTGATGGTTCTGTTGTTCGAACCAGAGCTGAAAGAAATCGACATGCTCAAACTCCTGAAGCTGACGCTTGTG
CATGACCTGGGCGAAGCCATCTCCGGAGATGTCCCCGCTCCACTCCAGTCGCCGGGTGACGACCGACAGGAACGCGAGAG
GCGGGACTTTCTGACCTTGTGCGAACCGCTGCCGGGTGACGTGGCTGGCGAGCTGACCTCCCTCTGGGATGAGTATGCAG
CGGCACGAACCTCTGAAGCCCGACTTGCCAAGGCGTTCGACAAGCTGGAGACCATGCTTCAGCACGTTCTGATGCCAAGG
CAAGCACCTTCATTTTATGAGTTCAACCTGGGTTACGGCCGTGATCGCACCGATTGCAGTGCTCTCACGCGCCAGTTGCG
TGACGAAGTCGACGAGCTGACCCGCACCATGATGACGGGCGCAGGACGGGAAATCGCCTGA

Antitoxin


Download         Length: 190 a.a.        Molecular weight: 21646.63 Da        Isoelectric Point: 7.3881

>AT55205 WP_062489195.1 NZ_CP011927:3970984-3971553 [Labrenzia sp. CP4]
MQTETAVLESSLGPSLRRWRVLNRVKQEALAHELGVSQTRISRWESGKSQLDDSDRAKITRLLRARPESAADKALLDLVS
RSAVPVHLVCDLTHRLLAISVPRACEWRAPVNEFLNRPLWRFASEGIRATEHRLTDYGWFEPDAPDIVYRTEHVDFPEMT
IPESIIRISRLPLSDGRFARLVREEQDAA

Download         Length: 570 bp

>AT55205 NZ_CP011927:3970984-3971553 [Labrenzia sp. CP4]
ATGCAAACAGAAACCGCCGTTCTTGAAAGCAGTCTTGGACCGTCGCTGCGGCGCTGGCGCGTACTGAACCGGGTCAAGCA
AGAAGCTCTGGCGCATGAACTTGGCGTCTCGCAGACGAGGATATCGCGCTGGGAGAGCGGCAAGTCGCAACTGGATGACA
GCGACAGGGCGAAGATCACCCGTCTGTTGAGGGCACGTCCGGAGAGCGCCGCCGACAAGGCCCTGCTTGATCTTGTCTCC
CGGTCCGCAGTTCCCGTGCATCTGGTCTGCGACCTCACACACAGGCTGCTGGCCATATCCGTACCGCGTGCCTGCGAATG
GCGCGCACCGGTGAACGAGTTTCTGAACCGGCCCCTATGGCGTTTTGCGTCCGAAGGCATCCGGGCAACGGAGCACAGAC
TGACCGACTATGGCTGGTTCGAGCCGGATGCTCCTGACATTGTCTACCGAACGGAACACGTCGATTTCCCGGAAATGACC
ATCCCGGAGAGCATCATCCGGATTTCGCGCCTGCCGCTGTCAGACGGACGGTTTGCGCGGCTGGTCCGTGAAGAACAGGA
TGCCGCATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References