Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 1223789..1224409 Replicon chromosome
Accession NZ_CP011918
Organism Burkholderia cenocepacia strain ST32 isolate 1232

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag TQ36_RS23065 Protein ID WP_058902847.1
Coordinates 1224092..1224409 (-) Length 106 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag TQ36_RS23060 Protein ID WP_058902846.1
Coordinates 1223789..1224088 (-) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
TQ36_RS23035 1219022..1220293 + 1272 WP_058902844.1 Rieske 2Fe-2S domain-containing protein -
TQ36_RS23040 1220309..1220785 + 477 WP_006490977.1 aromatic-ring-hydroxylating dioxygenase subunit beta -
TQ36_RS23045 1220821..1221147 + 327 WP_006496019.1 non-heme iron oxygenase ferredoxin subunit -
TQ36_RS23050 1221137..1222357 + 1221 WP_058902845.1 FAD-dependent oxidoreductase -
TQ36_RS23055 1222454..1223740 + 1287 WP_006490986.1 DUF445 domain-containing protein -
TQ36_RS23060 1223789..1224088 - 300 WP_058902846.1 putative addiction module antidote protein Antitoxin
TQ36_RS23065 1224092..1224409 - 318 WP_058902847.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
TQ36_RS23070 1224798..1226438 + 1641 WP_006490980.1 acetolactate synthase large subunit -
TQ36_RS23075 1226467..1227900 + 1434 WP_006490987.1 aldehyde dehydrogenase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(10-102)

Antitoxin

Uncharacterized protein HI1420

(5-93)


Sequences

Toxin        


Download         Length: 106 a.a.        Molecular weight: 11725.41 Da        Isoelectric Point: 8.0598

>T55197 WP_058902847.1 NZ_CP011918:c1224409-1224092 [Burkholderia cenocepacia]
MPYSPPAFSVRTTDVFDAWFAGLPDRLAKRRIQARIDRLSMGNPGDWKSAGSPVVEMRIDHGPGYRVYDVRRGTIWVILL
CGGDQSAQQADIRAAHAMLAHLDME

Download         Length: 318 bp

>T55197 NZ_CP011918:c1224409-1224092 [Burkholderia cenocepacia]
ATGCCCTACAGTCCTCCTGCATTCAGCGTCCGGACCACCGACGTCTTCGACGCCTGGTTTGCCGGCCTGCCCGATCGCCT
CGCCAAACGCCGCATCCAGGCGCGCATCGACCGCCTGTCGATGGGCAATCCGGGCGACTGGAAATCCGCCGGCTCCCCCG
TCGTCGAAATGCGTATCGACCACGGCCCGGGCTATCGCGTCTATGACGTGAGGCGCGGAACGATATGGGTCATCCTGCTC
TGCGGCGGCGATCAATCGGCGCAACAGGCCGACATCCGCGCCGCGCACGCAATGCTCGCGCACCTCGACATGGAGTGA

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 10635.07 Da        Isoelectric Point: 6.4771

>AT55197 WP_058902846.1 NZ_CP011918:c1224088-1223789 [Burkholderia cenocepacia]
MDKIKTRPWDSAEHLKTEDDMADYFDACLQEAGDDPAFIAHALGVIARARGMSQVARDAGLSREGLYKALSHDGNPNFGT
ILKVIKALGLQLHGAKAAA

Download         Length: 300 bp

>AT55197 NZ_CP011918:c1224088-1223789 [Burkholderia cenocepacia]
ATGGACAAGATCAAGACGCGGCCGTGGGATTCGGCCGAACACCTGAAAACCGAAGACGACATGGCCGACTACTTCGACGC
ATGCCTGCAGGAGGCCGGCGACGATCCGGCCTTCATCGCGCATGCGCTCGGCGTGATCGCCCGCGCACGCGGCATGTCGC
AGGTCGCACGCGATGCGGGCCTGTCGCGCGAAGGGCTGTACAAGGCGCTGTCGCACGACGGCAATCCGAACTTCGGCACG
ATCCTGAAAGTCATCAAAGCGCTCGGCCTGCAATTGCACGGCGCCAAGGCTGCCGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References