55119

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-relB/YoeB-YefM
Location 3793723..3794229 Replicon chromosome
Accession NZ_CP011853
Organism Gordonia phthalatica strain QH-11

Toxin (Protein)


Gene name yoeB Uniprot ID A0A0N9NK23
Locus tag ACH46_RS17875 Protein ID WP_062394124.1
Coordinates 3793975..3794229 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A0N9NE86
Locus tag ACH46_RS17870 Protein ID WP_062394123.1
Coordinates 3793723..3793974 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ACH46_RS17845 3788778..3789269 - 492 WP_062394118.1 hypothetical protein -
ACH46_RS17850 3789474..3790862 + 1389 WP_062394119.1 FAD-dependent oxidoreductase -
ACH46_RS17855 3790946..3791446 - 501 WP_062394120.1 hypothetical protein -
ACH46_RS17860 3791636..3792616 + 981 WP_062394121.1 iron chelate uptake ABC transporter family permease subunit -
ACH46_RS17865 3792613..3793668 + 1056 WP_062394122.1 iron ABC transporter permease -
ACH46_RS17870 3793723..3793974 + 252 WP_062394123.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
ACH46_RS17875 3793975..3794229 + 255 WP_062394124.1 Txe/YoeB family addiction module toxin Toxin
ACH46_RS17880 3794608..3795450 + 843 WP_062394125.1 nitrite reductase -
ACH46_RS17885 3795447..3796142 + 696 WP_062394126.1 precorrin-8X methylmutase -
ACH46_RS17890 3796139..3797671 + 1533 WP_062394127.1 precorrin-3B C(17)-methyltransferase -
ACH46_RS17895 3797668..3798894 + 1227 WP_062395600.1 bifunctional cobalt-precorrin-7 (C(5))-methyltransferase/cobalt-precorrin-6B (C(15))-methyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-70)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10103.58 Da        Isoelectric Point: 7.8760

>T55119 WP_062394124.1 NZ_CP011853:3793975-3794229 [Gordonia phthalatica]
MRLVWDPSAWNDYKHWQTADRRILKRINTLIDACLRDPFECIGKPEQLKYGASGAWSRRITDEHRLVYLVIDDDLIILQA
RYHY

Download         Length: 255 bp

>T55119 NZ_CP011853:3793975-3794229 [Gordonia phthalatica]
ATGCGCCTGGTCTGGGACCCCTCGGCCTGGAACGATTACAAGCACTGGCAGACTGCGGACCGCCGGATTCTGAAACGAAT
CAACACCCTGATCGATGCGTGCCTCCGCGACCCCTTCGAGTGCATCGGCAAGCCCGAACAACTCAAGTACGGAGCCTCGG
GAGCCTGGTCCAGGCGCATCACCGACGAGCACCGACTCGTCTACCTCGTCATCGACGACGACCTGATCATCCTCCAAGCG
CGATACCACTACTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9358.41 Da        Isoelectric Point: 5.0981

>AT55119 WP_062394123.1 NZ_CP011853:3793723-3793974 [Gordonia phthalatica]
MSISASEARKTLFPLIERVNADHEAVEIVSRHGNAVLMPADEYAAWQETAYLFRSPANARRLLDAYERARAGTTETHDLD
RDV

Download         Length: 252 bp

>AT55119 NZ_CP011853:3793723-3793974 [Gordonia phthalatica]
ATGTCCATCAGCGCCAGTGAGGCCCGTAAGACCCTGTTTCCCCTGATCGAGCGGGTCAATGCCGACCACGAGGCCGTCGA
GATCGTGTCCCGTCACGGCAATGCGGTTCTCATGCCCGCCGACGAGTACGCGGCATGGCAGGAGACGGCCTACCTGTTCC
GCTCCCCCGCCAACGCTCGCCGTCTGCTCGATGCTTACGAGCGTGCCCGTGCAGGCACGACAGAGACCCACGACCTCGAC
CGAGACGTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0N9NK23

Antitoxin

Source ID Structure
AlphaFold DB A0A0N9NE86

References