55089

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PfiT-PfiA/Phd(antitoxin)
Location 65470..66068 Replicon plasmid pacX50dB3a
Accession NZ_CP011837
Organism Azotobacter chroococcum strain B3

Toxin (Protein)


Gene name PfiT Uniprot ID -
Locus tag ACG10_RS23120 Protein ID WP_157731523.1
Coordinates 65470..65811 (-) Length 114 a.a.

Antitoxin (Protein)


Gene name PfiA Uniprot ID -
Locus tag ACG10_RS23125 Protein ID WP_089170202.1
Coordinates 65808..66068 (-) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ACG10_RS23105 62349..63097 + 749 WP_157731522.1 IS5 family transposase -
ACG10_RS23110 63180..64541 + 1362 WP_089170199.1 IS701-like element ISAzvi8 family transposase -
ACG10_RS23115 64692..65441 + 750 WP_089170200.1 IS5 family transposase -
ACG10_RS23120 65470..65811 - 342 WP_157731523.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
ACG10_RS23125 65808..66068 - 261 WP_089170202.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
ACG10_RS23130 66170..67102 - 933 WP_157731524.1 YqaJ viral recombinase family protein -
ACG10_RS23135 67099..68697 - 1599 WP_089170204.1 right-handed parallel beta-helix repeat-containing protein -
ACG10_RS23145 69956..70219 + 264 WP_089170165.1 ribbon-helix-helix protein, CopG family -
ACG10_RS23150 70182..70478 + 297 WP_089170205.1 type II toxin-antitoxin system RelE/ParE family toxin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..74783 74783
- inside IScluster/Tn - - 58512..69764 11252


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-99)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 114 a.a.        Molecular weight: 13012.83 Da        Isoelectric Point: 5.1133

>T55089 WP_157731523.1 NZ_CP011837:c65811-65470 [Azotobacter chroococcum]
MSFDVQFATTAETSLFSQIAHLEPYHGYDGAYEKLSTLVAEVIRRLADHPLGYPISAQASELGITHYRELNLDGYRVFYE
CDEEKRLVVVLLILGQRQSIEQQLIHYCLMFAR

Download         Length: 342 bp

>T55089 NZ_CP011837:c65811-65470 [Azotobacter chroococcum]
ATGAGCTTCGACGTTCAGTTTGCTACTACTGCTGAAACCAGCCTGTTTTCCCAGATCGCCCACCTGGAGCCGTACCACGG
CTATGACGGGGCCTATGAAAAGCTCTCCACCTTGGTGGCAGAAGTTATACGCCGCCTGGCCGATCACCCGTTGGGCTACC
CCATCAGCGCACAAGCCAGCGAGCTTGGGATCACCCATTACCGGGAGCTCAATCTCGACGGCTACCGCGTCTTCTATGAA
TGCGACGAGGAAAAGCGCCTCGTGGTGGTCCTGCTCATCCTGGGGCAGCGACAGAGCATCGAGCAGCAGCTGATCCACTA
CTGCCTGATGTTCGCTCGTTGA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9587.09 Da        Isoelectric Point: 9.0005

>AT55089 WP_089170202.1 NZ_CP011837:c66068-65808 [Azotobacter chroococcum]
MKIETISFLKKHAASLDLTEPMVITQNGLPAYVIESYTERKQRDETIALVKLLALGSRDKEQGKLVSGDTLLDRLAQRCQ
QPKGTS

Download         Length: 261 bp

>AT55089 NZ_CP011837:c66068-65808 [Azotobacter chroococcum]
ATGAAAATCGAGACGATCAGCTTCTTGAAGAAGCACGCCGCATCGTTGGATCTAACCGAACCCATGGTGATCACCCAGAA
CGGTCTGCCCGCCTATGTCATCGAGTCCTATACCGAACGCAAGCAGCGCGATGAGACGATTGCACTCGTCAAGCTCCTGG
CATTGGGTTCCCGCGACAAAGAGCAAGGCAAGCTGGTGTCGGGCGACACGCTCCTGGATCGGTTGGCACAACGATGCCAG
CAACCCAAAGGAACCTCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References