Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 4215169..4215950 Replicon chromosome
Accession NZ_CP011835
Organism Azotobacter chroococcum strain B3

Toxin (Protein)


Gene name tacT Uniprot ID -
Locus tag ACG10_RS19750 Protein ID WP_089169512.1
Coordinates 4215456..4215950 (+) Length 165 a.a.

Antitoxin (Protein)


Gene name tacA Uniprot ID -
Locus tag ACG10_RS19745 Protein ID WP_089169511.1
Coordinates 4215169..4215459 (+) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ACG10_RS19725 4210317..4211288 + 972 WP_089169507.1 glucokinase -
ACG10_RS19730 4211365..4211946 - 582 WP_089169508.1 hypothetical protein -
ACG10_RS19735 4212550..4214169 + 1620 WP_089169509.1 malate:quinone oxidoreductase -
ACG10_RS19740 4214264..4215037 + 774 WP_089169510.1 haloacid dehalogenase type II -
ACG10_RS19745 4215169..4215459 + 291 WP_089169511.1 DUF1778 domain-containing protein Antitoxin
ACG10_RS19750 4215456..4215950 + 495 WP_089169512.1 GNAT family N-acetyltransferase Toxin
ACG10_RS19755 4216030..4216785 - 756 WP_089169513.1 metallophosphoesterase -
ACG10_RS19760 4216857..4217756 - 900 WP_198318976.1 HNH endonuclease -
ACG10_RS19770 4218910..4219767 - 858 WP_089169516.1 restriction endonuclease -
ACG10_RS19775 4220000..4220266 - 267 WP_131256392.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(42-144)

Antitoxin

Vibrio phage ICP1, Orf50

(13-89)


Sequences

Toxin        


Download         Length: 165 a.a.        Molecular weight: 18176.99 Da        Isoelectric Point: 10.4178

>T55086 WP_089169512.1 NZ_CP011835:4215456-4215950 [Azotobacter chroococcum]
MTLRAPESLGPAHQLEAFDCGKPALNDWLLRHARQAQGSGSAKTFVVANGDRIAGYFSLTVGQVDTLEVPERIRKGMGQY
PIPVVILARRAVDRSYQGQGIGIGMLQDAIRRTLVIAEQAGIRALLTHPIDEQAAQFYGRFGFIASPLREQQRLLLLKDA
RRWL

Download         Length: 495 bp

>T55086 NZ_CP011835:4215456-4215950 [Azotobacter chroococcum]
ATGACCCTGCGCGCGCCCGAATCGCTGGGGCCGGCGCACCAGCTTGAGGCATTCGACTGCGGCAAGCCGGCGCTCAACGA
CTGGTTGCTGCGCCACGCCCGGCAGGCGCAAGGCAGCGGCTCGGCCAAGACCTTCGTCGTCGCCAACGGAGATCGTATCG
CCGGCTACTTCAGCCTGACGGTGGGACAGGTCGACACCTTGGAAGTACCTGAGCGCATTCGCAAAGGGATGGGGCAATAC
CCCATTCCGGTGGTGATCCTGGCGCGGCGGGCGGTCGATCGCTCCTACCAGGGGCAAGGCATCGGGATCGGCATGCTGCA
GGATGCCATCCGGCGAACCCTGGTCATCGCCGAACAGGCCGGCATCCGGGCCCTGCTGACCCACCCTATCGACGAGCAGG
CTGCGCAATTCTATGGGCGCTTCGGGTTCATCGCCTCACCGCTGCGAGAGCAGCAACGCCTGCTCCTGCTCAAGGACGCC
CGGCGCTGGCTCTGA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10622.97 Da        Isoelectric Point: 5.0789

>AT55086 WP_089169511.1 NZ_CP011835:4215169-4215459 [Azotobacter chroococcum]
MAATNSSATRSARLGLRATPEQEAVLRRAAEVARKSLTDFILDSACQAAEQTLLDQRLFMVSGNQYQTLMDLLERPAQDN
DGVRDLFARKAPWDAP

Download         Length: 291 bp

>AT55086 NZ_CP011835:4215169-4215459 [Azotobacter chroococcum]
ATGGCTGCCACGAACAGCAGCGCCACCCGCTCCGCCCGGCTCGGCCTGCGCGCCACTCCCGAACAGGAGGCGGTGCTTCG
TCGTGCCGCGGAGGTGGCCCGCAAGTCCCTGACCGACTTCATCCTGGACAGCGCCTGCCAGGCCGCGGAGCAGACCCTGC
TCGACCAGCGGCTGTTCATGGTATCGGGCAACCAGTACCAGACCCTGATGGATTTGCTGGAGCGCCCGGCCCAGGACAAC
GATGGCGTGCGCGATCTGTTCGCGCGCAAGGCGCCCTGGGATGCGCCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References