Detailed information of TA system TA055085

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 2754727..2755243
• Replicon: chromosome
• Accession: NZ_CP011835
• Organism: Azotobacter chroococcum strain B3

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: ACG10_RS12580
• Protein ID: WP_089168476.1
• Coordinates: 2754962..2755243 (+)
• Length: 94 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: ACG10_RS12575
• Protein ID: WP_089168475.1
• Coordinates: 2754727..2754972 (+)
• Length: 82 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ACG10_RS12570	2751716..2752957	-	1242	WP_089168474.1	hypothetical protein	-
ACG10_RS23750	2753445..2754542	+	1098	WP_157731452.1	hypothetical protein	-
ACG10_RS12575	2754727..2754972	+	246	WP_089168475.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
ACG10_RS12580	2754962..2755243	+	282	WP_089168476.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
ACG10_RS12585	2755305..2755697	-	393	WP_089168477.1	hypothetical protein	-
ACG10_RS12590	2755698..2758988	-	3291	WP_089168478.1	tape measure protein	-
ACG10_RS12595	2759132..2759437	-	306	WP_089168479.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	2751716..2785280	33564

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-83)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (8-71)

Sequences

Toxin

Protein

• Length: 94 a.a.
• Molecular weight: 10980.88 Da
• Isoelectric Point: 10.4563

>T55085 WP_089168476.1 NZ_CP011835:2754962-2755243 [Azotobacter chroococcum]
MTYSLEFLPSALKEWEKLEHTVREQLKKKLRERLELPKVPADALREMPNHYKIKLRASGYRLVYRVEDERVVVVVVAVGK
RERSAAYEKAKGR

Nucleotide

• Length: 282 bp

>T55085 NZ_CP011835:2754962-2755243 [Azotobacter chroococcum]
ATGACCTATAGCCTGGAGTTCCTGCCGTCCGCGCTGAAGGAATGGGAGAAGCTGGAGCACACGGTGCGCGAGCAGTTGAA
GAAGAAACTGCGCGAGCGTCTGGAGCTGCCCAAGGTGCCGGCCGACGCACTGCGCGAGATGCCGAACCACTACAAGATCA
AGCTACGCGCCTCGGGCTATCGGTTGGTGTACCGAGTGGAAGACGAGCGCGTGGTGGTGGTGGTGGTCGCCGTGGGCAAG
CGCGAGCGCAGCGCGGCCTATGAGAAGGCGAAGGGGCGGTAA

Antitoxin

Protein

• Length: 82 a.a.
• Molecular weight: 8616.84 Da
• Isoelectric Point: 4.3611

>AT55085 WP_089168475.1 NZ_CP011835:2754727-2754972 [Azotobacter chroococcum]
MQNVLADKAVSVSELKKNPSAVIGSANGGPVAVLNHNRVMGYMVPAEAFEAMVERLEDLELAELARSRAGETPVPVNLDD
L

Nucleotide

• Length: 246 bp

>AT55085 NZ_CP011835:2754727-2754972 [Azotobacter chroococcum]
ATGCAAAACGTACTGGCCGACAAGGCCGTCAGTGTGTCCGAGCTGAAGAAGAACCCGTCTGCGGTGATCGGCAGCGCCAA
TGGCGGGCCGGTGGCGGTGCTGAATCACAACCGGGTGATGGGTTACATGGTGCCGGCCGAAGCGTTCGAGGCAATGGTCG
AGCGGCTGGAAGACTTGGAGCTGGCCGAACTCGCCCGCTCTCGCGCCGGCGAAACACCCGTGCCGGTGAATCTGGATGAC
CTATAG