Detailed information of TA system TA055083

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): hicAB/HicA-HicB
• Location: 1715756..1716375
• Replicon: chromosome
• Accession: NZ_CP011835
• Organism: Azotobacter chroococcum strain B3

Toxin (Protein)

• Gene name: hicA
• Uniprot ID: -
• Locus tag: ACG10_RS07955
• Protein ID: WP_089167815.1
• Coordinates: 1715756..1715938 (+)
• Length: 61 a.a.

Antitoxin (Protein)

• Gene name: hicB
• Uniprot ID: -
• Locus tag: ACG10_RS07960
• Protein ID: WP_089167816.1
• Coordinates: 1715968..1716375 (+)
• Length: 136 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	1702601..1755478	52877

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• HicA mRNA interferase family (3-59)

Antitoxin

• HicB-like antitoxin of toxin-antitoxin system (3-128)

Sequences

Toxin

Protein

• Length: 61 a.a.
• Molecular weight: 6602.74 Da
• Isoelectric Point: 10.7162

>T55083 WP_089167815.1 NZ_CP011835:1715756-1715938 [Azotobacter chroococcum]
VNSREVIGLIEADGWYLVRVNGSHHHFKHPTKPGLVTIPHPKKDLLAKTVGSILKQAGIK

Nucleotide

• Length: 183 bp

>T55083 NZ_CP011835:1715756-1715938 [Azotobacter chroococcum]
GTGAATAGCCGTGAAGTAATAGGCCTCATTGAGGCGGACGGCTGGTATCTGGTGCGCGTGAATGGCAGTCATCACCACTT
CAAGCACCCGACCAAGCCTGGGCTGGTCACCATCCCGCACCCAAAGAAGGATCTGCTGGCCAAGACAGTCGGCAGCATCT
TGAAACAGGCCGGAATCAAGTAG

Antitoxin

Protein

• Length: 136 a.a.
• Molecular weight: 14379.23 Da
• Isoelectric Point: 4.5885

>AT55083 WP_089167816.1 NZ_CP011835:1715968-1716375 [Azotobacter chroococcum]
MLYPIAISPGDEQHAWGVEVPDIPGCFSAGDNLDDAMAMAREAIEGHLELLAEEGAQIPEASSVTTHASNPDYAGCTWAV
VDIDVTRYMGKAEKLNITLPGHLLARIDAYVKAHPEQKSRSGFLAAAALKALQHG

Nucleotide

• Length: 408 bp

>AT55083 NZ_CP011835:1715968-1716375 [Azotobacter chroococcum]
ATGCTTTATCCAATTGCAATCTCACCCGGCGACGAGCAGCACGCCTGGGGCGTCGAAGTGCCGGACATCCCCGGCTGTTT
CTCTGCGGGCGATAACTTGGACGATGCGATGGCGATGGCTCGCGAGGCCATCGAGGGGCATCTGGAACTGTTAGCCGAAG
AGGGCGCGCAGATCCCCGAGGCGAGCAGTGTGACCACGCATGCGAGCAATCCGGACTACGCCGGTTGCACCTGGGCGGTG
GTAGACATCGATGTGACCCGGTACATGGGTAAGGCAGAGAAACTGAACATCACCCTGCCGGGGCACCTGCTGGCCCGGAT
CGATGCCTATGTGAAGGCCCATCCGGAGCAGAAGAGCCGCTCCGGCTTCCTGGCTGCCGCAGCATTGAAGGCGTTGCAGC
ACGGCTGA