55075

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4649774..4650135 Replicon chromosome
Accession NZ_CP011827
Organism Xanthomonas citri pv. citri strain jx-6

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag AB890_RS20095 Protein ID WP_005914328.1
Coordinates 4649774..4649908 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID H8FG64
Locus tag AB890_RS20100 Protein ID WP_003486606.1
Coordinates 4649983..4650135 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AB890_RS20075 4644912..4646603 - 1692 WP_015471463.1 M20/M25/M40 family metallo-hydrolase -
AB890_RS20080 4646795..4647829 - 1035 WP_011052671.1 MBL fold metallo-hydrolase -
AB890_RS20085 4647868..4649157 - 1290 WP_015463705.1 tryptophan--tRNA ligase -
AB890_RS20090 4649338..4649547 - 210 WP_003486601.1 CsbD family protein -
AB890_RS20095 4649774..4649908 - 135 WP_005914328.1 entericidin A/B family lipoprotein Toxin
AB890_RS20100 4649983..4650135 - 153 WP_003486606.1 entericidin A/B family lipoprotein Antitoxin
AB890_RS20105 4650242..4651165 - 924 WP_005927745.1 arginase -
AB890_RS20110 4651486..4651938 + 453 WP_003486611.1 roadblock/LC7 domain-containing protein -
AB890_RS20115 4652002..4652361 + 360 WP_003486613.1 hypothetical protein -
AB890_RS20120 4652458..4653375 + 918 WP_011052673.1 hypothetical protein -
AB890_RS20125 4653372..4653914 + 543 WP_003486615.1 GTPase -
AB890_RS20130 4654352..4655035 + 684 WP_011052674.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T55075 WP_005914328.1 NZ_CP011827:c4649908-4649774 [Xanthomonas citri pv. citri]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T55075 NZ_CP011827:c4649908-4649774 [Xanthomonas citri pv. citri]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5122.07 Da        Isoelectric Point: 8.7942

>AT55075 WP_003486606.1 NZ_CP011827:c4650135-4649983 [Xanthomonas citri pv. citri]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGNKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT55075 NZ_CP011827:c4650135-4649983 [Xanthomonas citri pv. citri]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCCGGCGC
CGGCAAGGACATGCAGGGTGCGGGCAACAAGGTCGAGAAAACGGCCGAAAAATGCAGCGACGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2W7U6

Antitoxin

Source ID Structure
AlphaFold DB A0A828YLX6

References