Detailed information of TA system TA055059

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/VapC(toxin)
• Location: 142411..143046
• Replicon: chromosome
• Accession: NZ_CP011807
• Organism: Pandoraea faecigallinarum strain DSM 23572

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: A0A0H3WR92
• Locus tag: AB870_RS00585
• Protein ID: WP_047906525.1
• Coordinates: 142627..143046 (+)
• Length: 140 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: AB870_RS00580
• Protein ID: WP_157112188.1
• Coordinates: 142411..142611 (+)
• Length: 67 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
AB870_RS00565	137637..138485	+	849	WP_047906522.1	patatin-like phospholipase family protein	-
AB870_RS00570	138567..139577	-	1011	WP_047908624.1	D-2-hydroxyacid dehydrogenase family protein	-
AB870_RS00575	140331..142148	+	1818	WP_157112416.1	phosphoenolpyruvate carboxykinase (GTP)	-
AB870_RS00580	142411..142611	+	201	WP_157112188.1	DNA-binding protein	Antitoxin
AB870_RS00585	142627..143046	+	420	WP_047906525.1	type II toxin-antitoxin system VapC family toxin	Toxin
AB870_RS00590	143087..143719	-	633	WP_084663184.1	response regulator transcription factor	-
AB870_RS00595	143716..145101	-	1386	WP_047906526.1	cache domain-containing protein	-
AB870_RS00600	145577..147643	+	2067	WP_047906527.1	carbon starvation protein A	-
AB870_RS00605	147679..147876	+	198	WP_039394580.1	YbdD/YjiX family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (2-129)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 140 a.a.
• Molecular weight: 15966.41 Da
• Isoelectric Point: 7.5195

>T55059 WP_047906525.1 NZ_CP011807:142627-143046 [Pandoraea faecigallinarum]
MYLLDTNVISESRKGGGGDEGVQRFMRMTDRHHAQRFLSVITMGELQRGVRLLRHRNDARQASLVESWLEQLHIEYAEDI
LPIDLAICNVWARMRVPDPHHPIDKLIAATALVHKLVVVTRNVKDFTNVGVEVYNPFLQ

Nucleotide

• Length: 420 bp

>T55059 NZ_CP011807:142627-143046 [Pandoraea faecigallinarum]
ATGTATCTGCTCGATACCAATGTGATCAGCGAGAGCCGCAAGGGCGGCGGTGGCGATGAGGGCGTTCAGCGCTTCATGAG
AATGACGGATCGGCATCATGCGCAACGCTTCTTGTCCGTCATCACGATGGGCGAGTTGCAGCGAGGCGTGAGATTGCTTC
GGCACCGGAACGATGCTCGACAAGCGTCGCTGGTCGAGTCCTGGCTGGAGCAACTCCATATCGAATATGCCGAGGACATC
CTGCCAATCGATTTGGCGATCTGCAACGTTTGGGCGCGCATGCGCGTACCCGACCCGCATCATCCCATCGATAAGCTGAT
CGCCGCCACGGCGCTGGTGCACAAGCTCGTCGTGGTCACGCGCAACGTGAAAGATTTCACCAACGTGGGGGTCGAAGTTT
ACAACCCCTTCCTGCAGTAG

Antitoxin

Protein

• Length: 67 a.a.
• Molecular weight: 7498.60 Da
• Isoelectric Point: 4.5358

>AT55059 WP_157112188.1 NZ_CP011807:142411-142611 [Pandoraea faecigallinarum]
MMLIEGIDEQLMRSIESRAAQGGRTPEEEVLQILDRVARVPRFRTLGEALRAMPNVGLDSDFERIN

Nucleotide

• Length: 201 bp

>AT55059 NZ_CP011807:142411-142611 [Pandoraea faecigallinarum]
ATGATGTTGATCGAAGGAATCGACGAGCAATTGATGCGGTCGATCGAGTCGCGCGCGGCGCAAGGCGGGCGAACGCCGGA
AGAGGAGGTGCTGCAAATACTGGACAGGGTCGCGCGCGTTCCGCGGTTTCGCACCTTGGGAGAAGCACTCCGGGCGATGC
CGAATGTCGGTCTGGATAGCGACTTCGAACGAATCAATTAA

Structures

Toxin

• AlphaFold DB: A0A0H3WR92