Detailed information of TA system TA055035

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /BrnT(toxin)
• Location: 3371405..3371792
• Replicon: chromosome
• Accession: NZ_CP011797
• Organism: Reinekea forsetii strain Hel1_31_D35

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: REIFOR_RS15380
• Protein ID: WP_100258402.1
• Coordinates: 3371628..3371792 (-)
• Length: 55 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: REIFOR_RS15375
• Protein ID: WP_100258401.1
• Coordinates: 3371405..3371638 (-)
• Length: 78 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
REIFOR_RS15365	3367658..3369424	+	1767	WP_100258399.1	exodeoxyribonuclease V subunit alpha	-
REIFOR_RS15370	3369656..3370786	+	1131	WP_100258400.1	Fic family protein	-
REIFOR_RS15375	3371405..3371638	-	234	WP_100258401.1	CopG family transcriptional regulator	Antitoxin
REIFOR_RS15380	3371628..3371792	-	165	WP_100258402.1	BrnT family toxin	Toxin
REIFOR_RS15385	3372051..3372365	-	315	WP_100258812.1	ASCH domain-containing protein	-
REIFOR_RS15390	3372469..3372693	-	225	WP_100258403.1	BrnA antitoxin family protein	-
REIFOR_RS15395	3372690..3372977	-	288	WP_100258404.1	BrnT family toxin	-
REIFOR_RS15400	3373149..3373655	-	507	WP_100258405.1	cytochrome c	-
REIFOR_RS15405	3373659..3373850	-	192	WP_100258406.1	heavy-metal-associated domain-containing protein	-
REIFOR_RS15410	3373847..3376360	-	2514	WP_100258407.1	heavy metal translocating P-type ATPase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Integrative and Conjugative Element	-	-	3192782..3379018	186236

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Ribonuclease toxin, BrnT, of type II toxin-antitoxin system (3-48)

Antitoxin

• CopG antitoxin (13-70)

Sequences

Toxin

Protein

• Length: 55 a.a.
• Molecular weight: 6148.95 Da
• Isoelectric Point: 10.0826

>T55035 WP_100258402.1 NZ_CP011797:c3371792-3371628 [Reinekea forsetii]
MVQISASTLDEQRSLVIGQIGNNHWSAVITYRNSIIRIISVRRSRNSEVSLYES

Nucleotide

• Length: 165 bp

>T55035 NZ_CP011797:c3371792-3371628 [Reinekea forsetii]
TTGGTTCAGATTTCAGCTAGCACCCTAGATGAACAGAGATCACTAGTTATAGGTCAAATCGGAAACAACCACTGGTCAGC
TGTAATCACTTATAGAAACTCAATTATTCGTATAATTTCAGTTAGAAGGTCTAGAAATTCCGAGGTTTCGTTATATGAAA
GCTAA

Antitoxin

Protein

• Length: 78 a.a.
• Molecular weight: 9082.37 Da
• Isoelectric Point: 6.4701

>AT55035 WP_100258401.1 NZ_CP011797:c3371638-3371405 [Reinekea forsetii]
MKAKDFEEKFDANEEDLISNLDLSSVKRVNLQQKRVNVDFPVWMIESLDKEASRLGVTRQSIIKVWLAERLEHKTHQ

Nucleotide

• Length: 234 bp

>AT55035 NZ_CP011797:c3371638-3371405 [Reinekea forsetii]
ATGAAAGCTAAAGATTTTGAAGAGAAATTTGATGCAAACGAAGAAGACCTAATTTCAAATTTAGATCTTTCTTCAGTAAA
GCGCGTAAATCTGCAACAAAAAAGGGTTAATGTAGATTTTCCCGTTTGGATGATTGAGTCATTAGATAAAGAAGCTTCTA
GGCTGGGTGTTACACGCCAATCAATAATTAAAGTGTGGCTCGCTGAGCGTCTTGAGCATAAAACACACCAATAA