Detailed information of TA system TA055034

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): PP_4151-4152/excise(antitoxin)
• Location: 5535784..5536817
• Replicon: chromosome
• Accession: NZ_CP011789
• Organism: Pseudomonas putida strain PC2

Toxin (Protein)

• Gene name: PP_4152
• Uniprot ID: -
• Locus tag: AB688_RS24780
• Protein ID: WP_063546284.1
• Coordinates: 5535784..5536359 (-)
• Length: 192 a.a.

Antitoxin (Protein)

• Gene name: PP_4151
• Uniprot ID: -
• Locus tag: AB688_RS24785
• Protein ID: WP_063546286.1
• Coordinates: 5536359..5536817 (-)
• Length: 153 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
AB688_RS24755	5531457..5532647	-	1191	WP_063546276.1	pilus assembly protein	-
AB688_RS24760	5532644..5533888	-	1245	WP_063546278.1	type II and III secretion system protein family protein	-
AB688_RS24765	5533907..5534854	-	948	WP_063546280.1	Flp pilus assembly protein CpaB	-
AB688_RS24770	5535138..5535314	+	177	WP_063546282.1	Flp family type IVb pilin	-
AB688_RS24775	5535363..5535773	+	411	WP_054894187.1	response regulator	-
AB688_RS24780	5535784..5536359	-	576	WP_063546284.1	PIN domain-containing protein	Toxin
AB688_RS24785	5536359..5536817	-	459	WP_063546286.1	excisionase family DNA-binding protein	Antitoxin
AB688_RS24790	5536996..5538666	-	1671	WP_063546288.1	ShlB/FhaC/HecB family hemolysin secretion/activation protein	-
AB688_RS24795	5538802..5540388	-	1587	WP_063546290.1	collagen-like triple helix repeat-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (10-115)

Antitoxin

• Helix-turn-helix domain, group 17 (82-130)

Sequences

Toxin

Protein

• Length: 192 a.a.
• Molecular weight: 21557.93 Da
• Isoelectric Point: 5.2938

>T55034 WP_063546284.1 NZ_CP011789:c5536359-5535784 [Pseudomonas putida]
MRHSPFTTIYDACVLYPAPLRDLLVRLAGKGLYRARWSAQIDDEWKRNLLLKRRDLTRGQLDRISTLMEAAIPDALVVGH
ESLYPALNLPDPDDVHVLAAAIRSNAEVIVTFNLKDFPPSALRCFGVEAQHPDEFIMDLWDLDQAAVLEAVAEMRRSLVR
MPYTAEALLECYSRQGLPQTAGVLRDFALLI

Nucleotide

• Length: 576 bp

>T55034 NZ_CP011789:c5536359-5535784 [Pseudomonas putida]
ATGCGTCACTCACCGTTCACCACGATTTACGACGCATGCGTTCTTTATCCCGCCCCTTTGCGCGACTTGTTGGTCAGGCT
CGCTGGCAAGGGCCTTTACAGAGCCAGATGGAGCGCCCAGATCGATGATGAATGGAAAAGGAATCTATTGCTGAAACGGC
GGGATCTTACCCGGGGGCAATTGGACCGTATTTCCACACTGATGGAAGCGGCGATTCCCGATGCACTGGTTGTCGGTCAT
GAATCCTTGTACCCGGCTCTGAATCTGCCCGACCCCGATGACGTACATGTTCTTGCCGCCGCGATCAGAAGCAACGCGGA
AGTCATCGTGACGTTCAACCTGAAAGACTTTCCCCCATCCGCATTGCGCTGTTTCGGTGTAGAGGCACAGCACCCTGACG
AATTCATCATGGACTTGTGGGACCTCGATCAGGCTGCCGTTCTGGAGGCTGTGGCTGAAATGCGGCGCAGCTTGGTTCGT
ATGCCTTACACCGCCGAAGCCCTGCTGGAGTGCTATTCGAGGCAAGGCCTACCGCAGACGGCAGGGGTTTTGCGCGACTT
TGCCTTGTTGATCTGA

Antitoxin

Protein

• Length: 153 a.a.
• Molecular weight: 16846.21 Da
• Isoelectric Point: 5.2385

>AT55034 WP_063546286.1 NZ_CP011789:c5536817-5536359 [Pseudomonas putida]
MTVPIRTEFPEAREVAAAVQGQRDLAAVLCTQADMQRIEIYDADNKAHAVELPTSALRLLLDILGELAQGNSVRVVPVHA
ELTTQEAADLLSVSRPHLVKLLEEGALPHHTAGRHRRVLFSDLMIYKQQRDQASRKAMDDLTALSEELDLGY

Nucleotide

• Length: 459 bp

>AT55034 NZ_CP011789:c5536817-5536359 [Pseudomonas putida]
ATGACTGTGCCTATCCGTACCGAGTTTCCCGAGGCCCGTGAAGTAGCAGCCGCTGTGCAGGGGCAACGAGACCTGGCAGC
CGTGCTATGCACCCAGGCTGACATGCAGCGCATCGAGATCTACGACGCCGATAACAAGGCGCATGCCGTCGAACTGCCAA
CCAGTGCGCTGCGGTTGCTCCTGGATATACTGGGAGAGTTGGCACAGGGCAACTCTGTGCGGGTAGTGCCGGTCCACGCG
GAGCTGACCACGCAGGAGGCCGCGGATCTGCTGAGCGTTTCGCGCCCTCATCTGGTGAAACTGCTCGAGGAAGGAGCATT
GCCCCATCACACGGCCGGTCGACATCGTCGTGTTCTCTTCTCTGACCTGATGATCTACAAACAGCAGCGGGATCAGGCCA
GCCGCAAGGCGATGGACGACTTGACCGCGCTATCGGAAGAGCTTGACCTGGGGTATTGA