Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafN(antitoxin)
Location 1704029..1704594 Replicon chromosome
Accession NZ_CP011775
Organism Vibrio vulnificus strain FORC_016

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag FORC16_RS07835 Protein ID WP_060531549.1
Coordinates 1704029..1704316 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FORC16_RS07840 Protein ID WP_060531547.1
Coordinates 1704313..1704594 (-) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FORC16_RS23260 1699103..1699222 - 120 WP_071652258.1 DUF3265 domain-containing protein -
FORC16_RS07805 1699209..1699640 - 432 WP_060531555.1 hypothetical protein -
FORC16_RS07810 1699726..1700694 + 969 WP_081036190.1 IS30 family transposase -
FORC16_RS23265 1700887..1701009 - 123 WP_081036298.1 DUF3265 domain-containing protein -
FORC16_RS24225 1701362..1701454 - 93 WP_196374721.1 DUF3265 domain-containing protein -
FORC16_RS07815 1701481..1701726 - 246 WP_025523863.1 DUF2442 domain-containing protein -
FORC16_RS07820 1701704..1702024 - 321 WP_025523864.1 DUF4160 domain-containing protein -
FORC16_RS24520 1702051..1702281 - 231 WP_196374714.1 DUF3265 domain-containing protein -
FORC16_RS07825 1702244..1702723 - 480 WP_060531553.1 GNAT family N-acetyltransferase -
FORC16_RS23275 1702748..1702870 - 123 WP_081036297.1 DUF3265 domain-containing protein -
FORC16_RS07830 1702867..1703400 - 534 WP_196374713.1 (d)CMP kinase -
FORC16_RS23280 1703387..1703551 - 165 WP_081036211.1 DUF3265 domain-containing protein -
FORC16_RS07835 1704029..1704316 - 288 WP_060531549.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FORC16_RS07840 1704313..1704594 - 282 WP_060531547.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
FORC16_RS23285 1704617..1704795 - 179 Protein_1576 DUF3265 domain-containing protein -
FORC16_RS07845 1705266..1705763 - 498 WP_060531545.1 DUF2867 domain-containing protein -
FORC16_RS23290 1705773..1705883 - 111 WP_081036210.1 DUF3265 domain-containing protein -
FORC16_RS07850 1705901..1706356 - 456 WP_060531542.1 hypothetical protein -
FORC16_RS23295 1706375..1706563 - 189 WP_081036209.1 DUF3265 domain-containing protein -
FORC16_RS07855 1706594..1707562 + 969 WP_081036190.1 IS30 family transposase -
FORC16_RS07860 1707606..1708223 - 618 WP_060531540.1 HAD family phosphatase -
FORC16_RS23300 1708278..1708361 - 84 WP_081036296.1 DUF3265 domain-containing protein -
FORC16_RS23305 1708720..1708812 - 93 Protein_1584 DUF3265 domain-containing protein -
FORC16_RS07865 1708839..1709288 - 450 WP_060531538.1 GNAT family N-acetyltransferase -
FORC16_RS23310 1709315..1709407 - 93 WP_196374712.1 DUF3265 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1610914..1786420 175506
- inside Integron - - 1662584..1786420 123836


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(9-74)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 10946.63 Da        Isoelectric Point: 5.0746

>T55030 WP_060531549.1 NZ_CP011775:c1704316-1704029 [Vibrio vulnificus]
MKVVWSPLALQKLGDAAEFISLDNPVAAESWINEVFDKTDLLSSMPEMGRMVPELPHTNYREILFGHYRIIYSLSHEIRV
LTVRNCRQILTESDV

Download         Length: 288 bp

>T55030 NZ_CP011775:c1704316-1704029 [Vibrio vulnificus]
ATGAAAGTTGTCTGGTCACCACTAGCATTACAAAAGTTAGGTGATGCAGCCGAGTTTATTTCACTGGATAACCCAGTGGC
AGCAGAAAGCTGGATTAATGAGGTTTTTGATAAAACTGATTTACTCTCAAGTATGCCTGAAATGGGGCGAATGGTTCCTG
AGTTGCCTCATACCAATTACCGCGAAATCTTGTTTGGTCACTATCGCATCATATATAGCCTTAGCCATGAAATTCGCGTT
CTCACAGTACGAAATTGTCGTCAGATACTAACGGAAAGTGACGTGTAG

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10412.93 Da        Isoelectric Point: 5.8651

>AT55030 WP_060531547.1 NZ_CP011775:c1704594-1704313 [Vibrio vulnificus]
MSRIHFDQDIQPLSEFRAGVTSFIKQINETRRPLVITQRGKGVAVVLDVAEYEAMQEKIELLEEMRTAEAQLASGLGVSN
DDARAQVLGRIKK

Download         Length: 282 bp

>AT55030 NZ_CP011775:c1704594-1704313 [Vibrio vulnificus]
ATGAGCCGTATTCACTTCGACCAAGATATTCAGCCTTTATCTGAATTTCGTGCTGGCGTAACGTCATTTATAAAACAAAT
TAACGAAACTCGCAGACCACTAGTAATCACACAACGTGGTAAAGGTGTTGCAGTTGTCCTTGATGTTGCGGAATATGAAG
CAATGCAAGAGAAGATCGAGTTACTGGAAGAAATGCGTACTGCTGAAGCACAATTAGCTTCAGGTTTAGGTGTTTCCAAT
GATGACGCTCGCGCTCAAGTGTTGGGGCGTATTAAGAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References