Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/Phd(antitoxin)
Location 1664792..1665339 Replicon chromosome
Accession NZ_CP011775
Organism Vibrio vulnificus strain FORC_016

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag FORC16_RS07605 Protein ID WP_060531603.1
Coordinates 1664792..1665094 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FORC16_RS07610 Protein ID WP_060531602.1
Coordinates 1665082..1665339 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FORC16_RS07580 1660403..1660891 - 489 WP_060531609.1 hypothetical protein -
FORC16_RS23045 1660918..1661020 - 103 Protein_1483 DUF3265 domain-containing protein -
FORC16_RS07585 1661255..1662211 + 957 WP_060531432.1 IS110 family transposase -
FORC16_RS23050 1662597..1662689 - 93 WP_079858460.1 DUF3265 domain-containing protein -
FORC16_RS07590 1662704..1663054 - 351 WP_060531607.1 hypothetical protein -
FORC16_RS07595 1663272..1663679 - 408 WP_060531605.1 NUDIX hydrolase -
FORC16_RS23055 1663699..1663821 - 123 WP_081036310.1 DUF3265 domain-containing protein -
FORC16_RS07600 1664303..1664524 - 222 WP_005526706.1 VF530 family protein -
FORC16_RS23065 1664664..1664756 - 93 WP_196374716.1 DUF3265 domain-containing protein -
FORC16_RS07605 1664792..1665094 - 303 WP_060531603.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FORC16_RS07610 1665082..1665339 - 258 WP_060531602.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
FORC16_RS07615 1665552..1666190 - 639 WP_060531600.1 class I SAM-dependent methyltransferase -
FORC16_RS24200 1666620..1666730 - 111 WP_155521458.1 DUF3265 domain-containing protein -
FORC16_RS07620 1666773..1667420 - 648 WP_060531598.1 hypothetical protein -
FORC16_RS07625 1667555..1668223 - 669 WP_060531578.1 hypothetical protein -
FORC16_RS23070 1668263..1668355 - 93 WP_193288685.1 DUF3265 domain-containing protein -
FORC16_RS07630 1668401..1668925 - 525 WP_060531596.1 AAA family ATPase -
FORC16_RS23075 1668971..1669063 - 93 WP_081036221.1 DUF3265 domain-containing protein -
FORC16_RS07635 1669085..1669375 - 291 WP_060531595.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1610914..1786420 175506
- inside Integron - - 1662584..1786420 123836


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-69)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11685.61 Da        Isoelectric Point: 5.1765

>T55028 WP_060531603.1 NZ_CP011775:c1665094-1664792 [Vibrio vulnificus]
MAEIIWTEPALSDLNDIAEYIALENIVAAKQLVQTIFSKVERLQTFPESGRIPLELEHLSYREVVVNPCRVFYKQDGDKV
FILFVMRAERDLRKFLLSKQ

Download         Length: 303 bp

>T55028 NZ_CP011775:c1665094-1664792 [Vibrio vulnificus]
ATGGCTGAAATAATCTGGACTGAGCCAGCGTTATCTGACCTCAACGATATCGCTGAATACATCGCACTTGAAAATATCGT
AGCTGCAAAGCAGTTAGTGCAAACGATCTTCTCCAAAGTCGAACGCTTGCAAACTTTCCCAGAGTCAGGTCGTATTCCAC
TCGAGCTAGAACACTTAAGTTATCGTGAAGTTGTCGTTAATCCATGTCGTGTTTTCTATAAACAAGACGGTGACAAAGTG
TTTATTCTGTTTGTTATGCGTGCAGAGAGAGATTTGCGTAAGTTCCTGTTGAGTAAGCAGTAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9584.04 Da        Isoelectric Point: 5.7234

>AT55028 WP_060531602.1 NZ_CP011775:c1665339-1665082 [Vibrio vulnificus]
MKVELVTSLKRQATKILADLHDTKEPVLITEDGKPSAYLVDVDDYEFMQNRLAILEGIARGERALADGKVVSHDEAKDKM
SKWLK

Download         Length: 258 bp

>AT55028 NZ_CP011775:c1665339-1665082 [Vibrio vulnificus]
ATGAAAGTAGAACTAGTTACATCACTCAAACGTCAAGCAACTAAGATCCTCGCGGATCTCCACGACACCAAAGAACCAGT
GTTAATTACTGAGGATGGTAAGCCATCCGCGTATCTCGTTGATGTTGATGACTACGAGTTTATGCAAAATCGTTTAGCTA
TTCTTGAGGGTATTGCACGAGGTGAGCGTGCACTAGCTGACGGTAAAGTGGTAAGTCATGATGAAGCCAAGGACAAAATG
TCAAAATGGCTGAAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References