Detailed information of TA system TA055026

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): parDE/ParE-YefM
• Location: 1619122..1619671
• Replicon: chromosome
• Accession: NZ_CP011775
• Organism: Vibrio vulnificus strain FORC_016

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: FORC16_RS07330
• Protein ID: WP_060531668.1
• Coordinates: 1619372..1619671 (+)
• Length: 100 a.a.

Antitoxin (Protein)

• Gene name: parD
• Uniprot ID: -
• Locus tag: FORC16_RS07325
• Protein ID: WP_039553847.1
• Coordinates: 1619122..1619364 (+)
• Length: 81 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FORC16_RS22850	1614988..1615385	+	398	Protein_1396	transposase	-
FORC16_RS24140	1615386..1615445	-	60	Protein_1397	DUF3265 domain-containing protein	-
FORC16_RS07300	1615680..1616636	+	957	WP_060531432.1	IS110 family transposase	-
FORC16_RS07305	1616759..1617727	+	969	WP_081036190.1	IS30 family transposase	-
FORC16_RS07310	1617761..1618225	-	465	WP_060531669.1	ASCH domain-containing protein	-
FORC16_RS07315	1618396..1618698	-	303	WP_010448451.1	type II toxin-antitoxin system RelE/ParE family toxin	-
FORC16_RS07320	1618686..1618943	-	258	WP_005448240.1	type II toxin-antitoxin system Phd/YefM family antitoxin	-
FORC16_RS07325	1619122..1619364	+	243	WP_039553847.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
FORC16_RS07330	1619372..1619671	+	300	WP_060531668.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
FORC16_RS22860	1619733..1619825	-	93	WP_080772459.1	DUF3265 domain-containing protein	-
FORC16_RS07340	1620082..1621232	+	1151	WP_155521457.1	IS3 family transposase	-
FORC16_RS24155	1621262..1621429	+	168	Protein_1407	IS30 family transposase	-
FORC16_RS07350	1621927..1622598	-	672	WP_081036234.1	HAD-IA family hydrolase	-
FORC16_RS22865	1622595..1622744	-	150	WP_081036233.1	DUF3265 domain-containing protein	-
FORC16_RS07355	1623216..1623821	-	606	WP_060531664.1	hypothetical protein	-
FORC16_RS22875	1623793..1623966	-	174	WP_081036319.1	DUF3265 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	1610914..1786420	175506
	-	inside	IScluster/Tn	-	-	1615680..1626210	10530
	-	inside	Integron	-	-	1617761..1659080	41319

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (6-93)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-52)

Sequences

Toxin

Protein

• Length: 100 a.a.
• Molecular weight: 11401.99 Da
• Isoelectric Point: 9.6265

>T55026 WP_060531668.1 NZ_CP011775:1619372-1619671 [Vibrio vulnificus]
MQKNKYKLSNLAQSHLRKAKNYTVENFSELQWRNYKDTLLSGFQMLADNPGLGRSCDEVYPNGFYFPIGKHTAYFTKEDG
FILVVAVLGQSQLPQNHLK

Nucleotide

• Length: 300 bp

>T55026 NZ_CP011775:1619372-1619671 [Vibrio vulnificus]
ATGCAAAAGAACAAATACAAGCTAAGTAACTTAGCGCAATCTCACTTGCGCAAAGCAAAAAACTACACTGTTGAAAACTT
TTCTGAATTACAGTGGCGCAACTACAAAGACACTCTGCTATCAGGGTTTCAAATGCTAGCTGATAACCCTGGGTTAGGAA
GAAGCTGTGACGAGGTATACCCAAATGGCTTTTACTTCCCGATTGGAAAACACACCGCTTATTTCACTAAAGAAGATGGC
TTTATCTTAGTCGTAGCTGTCTTAGGTCAATCACAGCTCCCACAGAATCATTTGAAATAA

Antitoxin

Protein

• Length: 81 a.a.
• Molecular weight: 9031.26 Da
• Isoelectric Point: 5.6926

>AT55026 WP_039553847.1 NZ_CP011775:1619122-1619364 [Vibrio vulnificus]
MHTLTANDAKRNFGELLLSAQREPVKISKNSKDTVVVMSIRDFEELEAMKVEYLKHCFKSAKEDLNNGNAIDGESFLNSL

Nucleotide

• Length: 243 bp

>AT55026 NZ_CP011775:1619122-1619364 [Vibrio vulnificus]
ATGCATACATTAACAGCGAATGATGCCAAACGAAATTTCGGCGAACTACTTCTAAGCGCACAACGCGAGCCGGTAAAAAT
CAGCAAAAACAGTAAAGATACTGTCGTTGTCATGTCCATTCGTGACTTTGAAGAGTTAGAAGCTATGAAAGTTGAGTACC
TCAAACACTGCTTTAAGTCAGCTAAAGAAGACTTGAACAATGGAAACGCCATTGATGGCGAAAGCTTTCTAAATTCGCTG
TAA