Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 3338952..3339609 Replicon chromosome
Accession NZ_CP011650
Organism Enterobacter hormaechei strain CAV1669

Toxin (Protein)


Gene name cptA Uniprot ID A0A179PSF7
Locus tag AB285_RS16515 Protein ID WP_017382887.1
Coordinates 3338952..3339362 (-) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID G8LDB7
Locus tag AB285_RS16520 Protein ID WP_003863437.1
Coordinates 3339343..3339609 (-) Length 89 a.a.

Genomic Context


AB285_RS16510AB285_RS16525AB285_RS16535AB285_RS16540AB285_RS16495AB285_RS16500AB285_RS16505AB285_RS16515AB285_RS16520AB285_RS16530
Location: 3338429..3338950 (522 bp)
Type: Others
Protein ID: WP_015571793.1
Location: 3339904..3340884 (981 bp)
Type: Others
Protein ID: WP_032619082.1
Location: 3341922..3342653 (732 bp)
Type: Others
Protein ID: WP_015571796.1
Location: 3342770..3344203 (1434 bp)
Type: Others
Protein ID: WP_017382891.1
Location: 3334950..3336683 (1734 bp)
Type: Others
Protein ID: WP_023304383.1
Location: 3336689..3337402 (714 bp)
Type: Others
Protein ID: WP_023295380.1
Location: 3337431..3338327 (897 bp)
Type: Others
Protein ID: WP_023304385.1
Location: 3338952..3339362 (411 bp)
Type: Toxin
Protein ID: WP_017382887.1
Location: 3339343..3339609 (267 bp)
Type: Antitoxin
Protein ID: WP_003863437.1
Location: 3340996..3341655 (660 bp)
Type: Others
Protein ID: WP_003863433.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
AB285_RS164953334950..3336683-1734WP_023304383.1single-stranded-DNA-specific exonuclease RecJ-
AB285_RS165003336689..3337402-714WP_023295380.1bifunctional protein-disulfide isomerase/oxidoreductase DsbC-
AB285_RS165053337431..3338327-897WP_023304385.1site-specific tyrosine recombinase XerD-
AB285_RS165103338429..3338950+522WP_015571793.1flavodoxin FldB-
AB285_RS165153338952..3339362-411WP_017382887.1protein YgfXToxin
AB285_RS165203339343..3339609-267WP_003863437.1FAD assembly factor SdhEAntitoxin
AB285_RS165253339904..3340884+981WP_032619082.1tRNA-modifying protein YgfZ-
AB285_RS165303340996..3341655-660WP_003863433.1hemolysin III family protein-
AB285_RS165353341922..3342653+732WP_015571796.1MurR/RpiR family transcriptional regulator-
AB285_RS165403342770..3344203+1434WP_017382891.16-phospho-beta-glucosidase BglA-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(3-132)

Antitoxin

(7-79)


Sequences


Toxin        


Download         Length: 137 a.a.        Molecular weight: 16321.21 Da        Isoelectric Point: 11.4775

>T54782 WP_017382887.1 NZ_CP011650:c3339362-3338952 [Enterobacter hormaechei]
VVLWQSDLRVSWRSQWMSLLLHGLVAALVLLVPWPLSYTPLWLLLLSFVVFDSVRSQRRINARQGEIKLLMDSRLRWQGK
EWEMMGTPWMLNTGMMLRLRRVEDNRRQHLWLAADSMDPAEWRDLRRLIVQQPTQE

Download         Length: 411 bp

>T54782 NZ_CP011650:c3339362-3338952 [Enterobacter hormaechei]
GTGGTCCTGTGGCAATCTGATCTTCGCGTCTCGTGGCGCTCACAGTGGATGTCCTTACTGCTCCACGGGCTGGTGGCGGC
ACTGGTGTTATTGGTGCCGTGGCCGCTTAGCTATACCCCTCTGTGGTTGCTATTGCTGTCGTTTGTGGTGTTTGACAGCG
TGCGCAGCCAGCGTCGAATCAACGCCCGTCAGGGTGAAATTAAGCTGCTGATGGATTCTCGCCTGCGCTGGCAGGGAAAA
GAGTGGGAGATGATGGGGACGCCGTGGATGCTTAATACCGGGATGATGCTACGGCTGCGTCGGGTCGAGGATAACCGTCG
CCAGCACCTGTGGCTGGCCGCAGACAGTATGGATCCCGCGGAGTGGCGAGATCTGCGCCGGTTGATCGTGCAACAGCCGA
CGCAGGAGTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10526.96 Da        Isoelectric Point: 4.8310

>AT54782 WP_003863437.1 NZ_CP011650:c3339609-3339343 [Enterobacter hormaechei]
MDINNKARIHWACRRGMRELDISIMPFFEYEYDSLSDDDKRLFVRLLESDDPDLFNWLMNHGKPADTELQRMVQLIQTRN
QERGPVAI

Download         Length: 267 bp

>AT54782 NZ_CP011650:c3339609-3339343 [Enterobacter hormaechei]
ATGGATATTAACAACAAGGCCCGTATTCACTGGGCGTGCCGTCGCGGCATGCGTGAACTTGATATCTCCATCATGCCTTT
CTTCGAGTATGAGTACGACAGCTTAAGCGATGACGATAAGCGCCTGTTTGTCCGTCTGCTTGAGTCTGACGATCCGGATT
TATTCAACTGGCTGATGAATCACGGCAAGCCCGCCGACACCGAGTTGCAACGGATGGTGCAATTAATTCAAACACGGAAT
CAGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
AlphaFold DBA0A179PSF7


Antitoxin

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Source
ID
Structure
AlphaFold DBA0A837F8P5

References