Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | IV | Classification (family/domain) | cptAB/Cpta(toxin) |
Location | 3338952..3339609 | Replicon | chromosome |
Accession | NZ_CP011650 | ||
Organism | Enterobacter hormaechei strain CAV1669 |
Toxin (Protein)
Gene name | cptA | Uniprot ID | A0A179PSF7 |
Locus tag | AB285_RS16515 | Protein ID | WP_017382887.1 |
Coordinates | 3338952..3339362 (-) | Length | 137 a.a. |
Antitoxin (Protein)
Gene name | cptB | Uniprot ID | G8LDB7 |
Locus tag | AB285_RS16520 | Protein ID | WP_003863437.1 |
Coordinates | 3339343..3339609 (-) | Length | 89 a.a. |
Genomic Context
Location: 3338429..3338950 (522 bp)
Type: Others
Protein ID: WP_015571793.1
Type: Others
Protein ID: WP_015571793.1
Location: 3339904..3340884 (981 bp)
Type: Others
Protein ID: WP_032619082.1
Type: Others
Protein ID: WP_032619082.1
Location: 3341922..3342653 (732 bp)
Type: Others
Protein ID: WP_015571796.1
Type: Others
Protein ID: WP_015571796.1
Location: 3342770..3344203 (1434 bp)
Type: Others
Protein ID: WP_017382891.1
Type: Others
Protein ID: WP_017382891.1
Location: 3334950..3336683 (1734 bp)
Type: Others
Protein ID: WP_023304383.1
Type: Others
Protein ID: WP_023304383.1
Location: 3336689..3337402 (714 bp)
Type: Others
Protein ID: WP_023295380.1
Type: Others
Protein ID: WP_023295380.1
Location: 3337431..3338327 (897 bp)
Type: Others
Protein ID: WP_023304385.1
Type: Others
Protein ID: WP_023304385.1
Location: 3338952..3339362 (411 bp)
Type: Toxin
Protein ID: WP_017382887.1
Type: Toxin
Protein ID: WP_017382887.1
Location: 3339343..3339609 (267 bp)
Type: Antitoxin
Protein ID: WP_003863437.1
Type: Antitoxin
Protein ID: WP_003863437.1
Location: 3340996..3341655 (660 bp)
Type: Others
Protein ID: WP_003863433.1
Type: Others
Protein ID: WP_003863433.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
AB285_RS16495 | 3334950..3336683 | - | 1734 | WP_023304383.1 | single-stranded-DNA-specific exonuclease RecJ | - |
AB285_RS16500 | 3336689..3337402 | - | 714 | WP_023295380.1 | bifunctional protein-disulfide isomerase/oxidoreductase DsbC | - |
AB285_RS16505 | 3337431..3338327 | - | 897 | WP_023304385.1 | site-specific tyrosine recombinase XerD | - |
AB285_RS16510 | 3338429..3338950 | + | 522 | WP_015571793.1 | flavodoxin FldB | - |
AB285_RS16515 | 3338952..3339362 | - | 411 | WP_017382887.1 | protein YgfX | Toxin |
AB285_RS16520 | 3339343..3339609 | - | 267 | WP_003863437.1 | FAD assembly factor SdhE | Antitoxin |
AB285_RS16525 | 3339904..3340884 | + | 981 | WP_032619082.1 | tRNA-modifying protein YgfZ | - |
AB285_RS16530 | 3340996..3341655 | - | 660 | WP_003863433.1 | hemolysin III family protein | - |
AB285_RS16535 | 3341922..3342653 | + | 732 | WP_015571796.1 | MurR/RpiR family transcriptional regulator | - |
AB285_RS16540 | 3342770..3344203 | + | 1434 | WP_017382891.1 | 6-phospho-beta-glucosidase BglA | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
No matching records found |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 137 a.a. Molecular weight: 16321.21 Da Isoelectric Point: 11.4775
>T54782 WP_017382887.1 NZ_CP011650:c3339362-3338952 [Enterobacter hormaechei]
VVLWQSDLRVSWRSQWMSLLLHGLVAALVLLVPWPLSYTPLWLLLLSFVVFDSVRSQRRINARQGEIKLLMDSRLRWQGK
EWEMMGTPWMLNTGMMLRLRRVEDNRRQHLWLAADSMDPAEWRDLRRLIVQQPTQE
VVLWQSDLRVSWRSQWMSLLLHGLVAALVLLVPWPLSYTPLWLLLLSFVVFDSVRSQRRINARQGEIKLLMDSRLRWQGK
EWEMMGTPWMLNTGMMLRLRRVEDNRRQHLWLAADSMDPAEWRDLRRLIVQQPTQE
Download Length: 411 bp
>T54782 NZ_CP011650:c3339362-3338952 [Enterobacter hormaechei]
GTGGTCCTGTGGCAATCTGATCTTCGCGTCTCGTGGCGCTCACAGTGGATGTCCTTACTGCTCCACGGGCTGGTGGCGGC
ACTGGTGTTATTGGTGCCGTGGCCGCTTAGCTATACCCCTCTGTGGTTGCTATTGCTGTCGTTTGTGGTGTTTGACAGCG
TGCGCAGCCAGCGTCGAATCAACGCCCGTCAGGGTGAAATTAAGCTGCTGATGGATTCTCGCCTGCGCTGGCAGGGAAAA
GAGTGGGAGATGATGGGGACGCCGTGGATGCTTAATACCGGGATGATGCTACGGCTGCGTCGGGTCGAGGATAACCGTCG
CCAGCACCTGTGGCTGGCCGCAGACAGTATGGATCCCGCGGAGTGGCGAGATCTGCGCCGGTTGATCGTGCAACAGCCGA
CGCAGGAGTAA
GTGGTCCTGTGGCAATCTGATCTTCGCGTCTCGTGGCGCTCACAGTGGATGTCCTTACTGCTCCACGGGCTGGTGGCGGC
ACTGGTGTTATTGGTGCCGTGGCCGCTTAGCTATACCCCTCTGTGGTTGCTATTGCTGTCGTTTGTGGTGTTTGACAGCG
TGCGCAGCCAGCGTCGAATCAACGCCCGTCAGGGTGAAATTAAGCTGCTGATGGATTCTCGCCTGCGCTGGCAGGGAAAA
GAGTGGGAGATGATGGGGACGCCGTGGATGCTTAATACCGGGATGATGCTACGGCTGCGTCGGGTCGAGGATAACCGTCG
CCAGCACCTGTGGCTGGCCGCAGACAGTATGGATCCCGCGGAGTGGCGAGATCTGCGCCGGTTGATCGTGCAACAGCCGA
CGCAGGAGTAA
Antitoxin
Download Length: 89 a.a. Molecular weight: 10526.96 Da Isoelectric Point: 4.8310
>AT54782 WP_003863437.1 NZ_CP011650:c3339609-3339343 [Enterobacter hormaechei]
MDINNKARIHWACRRGMRELDISIMPFFEYEYDSLSDDDKRLFVRLLESDDPDLFNWLMNHGKPADTELQRMVQLIQTRN
QERGPVAI
MDINNKARIHWACRRGMRELDISIMPFFEYEYDSLSDDDKRLFVRLLESDDPDLFNWLMNHGKPADTELQRMVQLIQTRN
QERGPVAI
Download Length: 267 bp
>AT54782 NZ_CP011650:c3339609-3339343 [Enterobacter hormaechei]
ATGGATATTAACAACAAGGCCCGTATTCACTGGGCGTGCCGTCGCGGCATGCGTGAACTTGATATCTCCATCATGCCTTT
CTTCGAGTATGAGTACGACAGCTTAAGCGATGACGATAAGCGCCTGTTTGTCCGTCTGCTTGAGTCTGACGATCCGGATT
TATTCAACTGGCTGATGAATCACGGCAAGCCCGCCGACACCGAGTTGCAACGGATGGTGCAATTAATTCAAACACGGAAT
CAGGAACGTGGTCCTGTGGCAATCTGA
ATGGATATTAACAACAAGGCCCGTATTCACTGGGCGTGCCGTCGCGGCATGCGTGAACTTGATATCTCCATCATGCCTTT
CTTCGAGTATGAGTACGACAGCTTAAGCGATGACGATAAGCGCCTGTTTGTCCGTCTGCTTGAGTCTGACGATCCGGATT
TATTCAACTGGCTGATGAATCACGGCAAGCCCGCCGACACCGAGTTGCAACGGATGGTGCAATTAATTCAAACACGGAAT
CAGGAACGTGGTCCTGTGGCAATCTGA
Structures
Toxin
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Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A179PSF7 |
Antitoxin
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Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A837F8P5 |