54761

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4524753..4524898 Replicon chromosome
Accession NZ_CP011647
Organism Klebsiella pneumoniae strain CAV1596

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4524760..4524862 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4524753..4524898 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AB187_RS24150 4520285..4521718 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
AB187_RS24155 4521834..4522073 + 240 WP_002911393.1 YebV family protein -
AB187_RS24160 4522171..4522362 + 192 WP_002911395.1 YebW family protein -
AB187_RS24165 4522359..4523012 - 654 WP_002911396.1 protein-serine/threonine phosphatase -
AB187_RS24170 4523169..4524137 + 969 WP_004151446.1 VirK/YbjX family protein -
AB187_RS30575 4524242..4524385 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 4524753..4524898 + 146 - - Antitoxin
- 4524760..4524862 - 103 - - Toxin
AB187_RS24180 4525021..4525359 - 339 WP_002911404.1 YebY family protein -
AB187_RS24185 4525376..4526245 - 870 WP_004151447.1 copper homeostasis membrane protein CopD -
AB187_RS24190 4526249..4526623 - 375 WP_004151448.1 CopC domain-containing protein YobA -
AB187_RS24195 4526736..4526966 + 231 WP_002911406.1 DNA polymerase III subunit theta -
AB187_RS24200 4527045..4527704 + 660 WP_002911407.1 exodeoxyribonuclease X -
AB187_RS24205 4527708..4529768 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T54761 NZ_CP011647:c4524862-4524760 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT54761 NZ_CP011647:4524753-4524898 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References