Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 438786..438926 | Replicon | chromosome |
| Accession | NZ_CP011642 | ||
| Organism | Serratia marcescens strain CAV1492 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 438786..438882 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 438786..438926 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| AB188_RS03905 | 433871..434086 | - | 216 | WP_025302459.1 | helix-turn-helix transcriptional regulator | - |
| AB188_RS03910 | 434094..434657 | - | 564 | WP_033642723.1 | DUF2975 domain-containing protein | - |
| AB188_RS03915 | 434815..436014 | - | 1200 | WP_047727768.1 | trans-2-enoyl-CoA reductase family protein | - |
| AB188_RS03920 | 436301..436603 | + | 303 | WP_047727769.1 | hypothetical protein | - |
| AB188_RS03925 | 436654..437004 | - | 351 | WP_033638116.1 | DUF4377 domain-containing protein | - |
| AB188_RS03935 | 438036..438365 | + | 330 | WP_038875697.1 | DUF1493 family protein | - |
| - | 438786..438882 | - | 97 | - | - | Toxin |
| - | 438786..438926 | + | 141 | - | - | Antitoxin |
| AB188_RS03940 | 439024..439365 | - | 342 | WP_025302452.1 | YebY family protein | - |
| AB188_RS03945 | 439435..440316 | - | 882 | WP_038875842.1 | copper homeostasis membrane protein CopD | - |
| AB188_RS03950 | 440319..440735 | - | 417 | WP_047727770.1 | CopC domain-containing protein YobA | - |
| AB188_RS03955 | 441029..441532 | - | 504 | WP_047727771.1 | non-heme ferritin | - |
| AB188_RS03960 | 441873..442103 | + | 231 | WP_033638067.1 | DNA polymerase III subunit theta | - |
| AB188_RS03965 | 442168..442605 | - | 438 | WP_038874510.1 | IS200/IS605 family transposase | - |
| AB188_RS03970 | 442760..443713 | - | 954 | WP_047730746.1 | prolyl aminopeptidase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Genomic island | - | - | 436654..452118 | 15464 | |
| - | flank | IS/Tn | - | - | 442168..442656 | 488 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 97 bp
>T54726 NZ_CP011642:c438882-438786 [Serratia marcescens]
AACAAGCCCTGCATTAAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTAGACCGAATATAGGAATC
GTATTCGGTCTTTTTTT
AACAAGCCCTGCATTAAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTAGACCGAATATAGGAATC
GTATTCGGTCTTTTTTT
Antitoxin
Download Length: 141 bp
>AT54726 NZ_CP011642:438786-438926 [Serratia marcescens]
AAAAAAAGACCGAATACGATTCCTATATTCGGTCTAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCAT
TTAATGCAGGGCTTGTTCAGCCGTGCACTTTAAGAGTAGCCTACCGCGCCAGTTTTGCCAG
AAAAAAAGACCGAATACGATTCCTATATTCGGTCTAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCAT
TTAATGCAGGGCTTGTTCAGCCGTGCACTTTAAGAGTAGCCTACCGCGCCAGTTTTGCCAG
