Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4142543..4142688 Replicon chromosome
Accession NZ_CP011624
Organism Klebsiella pneumoniae strain CAV1344

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4142579..4142681 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4142543..4142688 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AB186_RS23590 4137673..4139733 + 2061 WP_040213005.1 oligopeptidase B -
AB186_RS23595 4139737..4140396 - 660 WP_021440386.1 exodeoxyribonuclease X -
AB186_RS23600 4140475..4140705 - 231 WP_002911406.1 DNA polymerase III subunit theta -
AB186_RS23605 4140818..4141192 + 375 WP_004151448.1 CopC domain-containing protein YobA -
AB186_RS23610 4141196..4142065 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
AB186_RS23615 4142082..4142420 + 339 WP_002911404.1 YebY family protein -
- 4142543..4142688 - 146 - - Antitoxin
- 4142579..4142681 + 103 - - Toxin
AB186_RS31970 4143056..4143199 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
AB186_RS23625 4143304..4144272 - 969 WP_004151446.1 VirK/YbjX family protein -
AB186_RS23630 4144429..4145082 + 654 WP_009484457.1 protein-serine/threonine phosphatase -
AB186_RS23635 4145079..4145270 - 192 WP_002911395.1 YebW family protein -
AB186_RS23640 4145368..4145607 - 240 WP_002911393.1 YebV family protein -
AB186_RS23645 4145723..4147156 - 1434 WP_032415191.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T54716 NZ_CP011624:4142579-4142681 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT54716 NZ_CP011624:c4142688-4142543 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References