Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 4034204..4034861 Replicon chromosome
Accession NZ_CP011591
Organism Enterobacter asburiae strain CAV1043

Toxin (Protein)


Gene name cptA Uniprot ID A0A1H8U0Q4
Locus tag AB190_RS20935 Protein ID WP_021242050.1
Coordinates 4034451..4034861 (+) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID V3PWU7
Locus tag AB190_RS20930 Protein ID WP_010435322.1
Coordinates 4034204..4034470 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AB190_RS20900 4029386..4030819 - 1434 WP_047743832.1 6-phospho-beta-glucosidase BglA -
AB190_RS20905 4030936..4031667 - 732 WP_047743834.1 MurR/RpiR family transcriptional regulator -
AB190_RS20910 4031719..4032030 + 312 WP_047743835.1 N(4)-acetylcytidine aminohydrolase -
AB190_RS20920 4032196..4032855 + 660 WP_047743838.1 hemolysin III family protein -
AB190_RS20925 4032929..4033909 - 981 WP_047743840.1 tRNA-modifying protein YgfZ -
AB190_RS20930 4034204..4034470 + 267 WP_010435322.1 FAD assembly factor SdhE Antitoxin
AB190_RS20935 4034451..4034861 + 411 WP_021242050.1 protein YgfX Toxin
AB190_RS20940 4034868..4035389 - 522 WP_023309099.1 flavodoxin FldB -
AB190_RS20945 4035491..4036387 + 897 WP_023309098.1 site-specific tyrosine recombinase XerD -
AB190_RS20950 4036416..4037129 + 714 WP_047743841.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
AB190_RS20955 4037135..4038868 + 1734 WP_047743842.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 16097.08 Da        Isoelectric Point: 10.9468

>T54652 WP_021242050.1 NZ_CP011591:4034451-4034861 [Enterobacter asburiae]
VVLWQSDLRVSWRSQWMSLLLHGLVAAFVLLMPWPLSYTPLWLLLLSFVVFDSVRSQRRINARQGEIKLLMDSRLRWQGK
EWDILGMPWMLNCGMMLRLRKVDGGRCQHLWLAADSMDAAEWRDLRRMLLQQTTQG

Download         Length: 411 bp

>T54652 NZ_CP011591:4034451-4034861 [Enterobacter asburiae]
GTGGTCCTGTGGCAATCTGATCTTCGCGTCTCGTGGCGCTCGCAGTGGATGTCTTTATTGCTCCACGGCCTGGTTGCGGC
CTTTGTTTTACTGATGCCGTGGCCGCTGAGCTATACGCCGCTGTGGCTGCTGTTACTGTCGTTTGTCGTTTTTGACAGCG
TACGCAGCCAGCGTCGCATTAATGCCCGTCAGGGAGAGATTAAATTACTGATGGATTCCCGCCTGCGCTGGCAGGGTAAA
GAGTGGGATATTCTCGGTATGCCCTGGATGCTCAACTGCGGCATGATGTTACGGTTACGCAAGGTGGACGGCGGGCGTTG
CCAGCATCTGTGGCTGGCGGCTGACAGTATGGATGCTGCCGAGTGGCGGGACCTGCGCCGGATGCTGTTGCAACAAACGA
CGCAGGGGTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10555.02 Da        Isoelectric Point: 5.1340

>AT54652 WP_010435322.1 NZ_CP011591:4034204-4034470 [Enterobacter asburiae]
MDINNKARIHWACRRGMRELDISIMPFFEYEYDSLSDDDKRLFVRLLESDDPDLFNWLMNHGKPADTELQRMVQLIQTRN
RERGPVAI

Download         Length: 267 bp

>AT54652 NZ_CP011591:4034204-4034470 [Enterobacter asburiae]
ATGGATATTAACAACAAGGCCCGTATTCACTGGGCGTGCCGTCGCGGCATGCGTGAACTTGATATTTCCATCATGCCTTT
CTTCGAATATGAGTATGACAGCTTAAGCGATGATGATAAGCGTCTGTTTGTTCGCCTGCTTGAGTCTGACGATCCGGATT
TATTCAACTGGCTGATGAACCACGGCAAACCCGCCGACACCGAGTTGCAACGGATGGTGCAATTAATTCAAACACGGAAT
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1H8U0Q4

Antitoxin

Source ID Structure
AlphaFold DB V3PWU7

References