Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 1531015..1531159 | Replicon | chromosome |
| Accession | NZ_CP011578 | ||
| Organism | Klebsiella pneumoniae strain CAV1392 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 1531021..1531123 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 1531015..1531159 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| ABY63_RS08975 | 1526303..1526731 | + | 429 | WP_032419788.1 | type II toxin-antitoxin system PemK/MazF family toxin | - |
| ABY63_RS30090 | 1526981..1527454 | - | 474 | WP_129587469.1 | hypothetical protein | - |
| ABY63_RS08980 | 1527500..1528197 | - | 698 | Protein_1509 | IS1 family transposase | - |
| ABY63_RS08985 | 1528231..1529262 | - | 1032 | WP_032419793.1 | hypothetical protein | - |
| ABY63_RS30095 | 1530051..1530530 | - | 480 | WP_032419797.1 | lysis protein | - |
| ABY63_RS08995 | 1530529..1530888 | + | 360 | WP_077253379.1 | tyrosine-type recombinase/integrase | - |
| - | 1531015..1531159 | + | 145 | - | - | Antitoxin |
| - | 1531021..1531123 | - | 103 | - | - | Toxin |
| ABY63_RS09000 | 1531282..1531620 | - | 339 | WP_002911404.1 | YebY family protein | - |
| ABY63_RS09005 | 1531637..1532506 | - | 870 | WP_020956678.1 | copper homeostasis membrane protein CopD | - |
| ABY63_RS09010 | 1532510..1532884 | - | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| ABY63_RS09015 | 1532997..1533227 | + | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| ABY63_RS09020 | 1533306..1533965 | + | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| ABY63_RS09025 | 1533969..1536029 | - | 2061 | WP_032419801.1 | oligopeptidase B | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 1515456..1535996 | 20540 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T54582 NZ_CP011578:c1531123-1531021 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 145 bp
>AT54582 NZ_CP011578:1531015-1531159 [Klebsiella pneumoniae]
ACATATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
ACATATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
