Detailed information of TA system TA054536

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relE-yefM/YoeB-YefM
• Location: 1118472..1118977
• Replicon: chromosome
• Accession: NZ_CP011567
• Organism: Pseudomonas sp. GR 6-02

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: PGR6_RS04805
• Protein ID: WP_064616223.1
• Coordinates: 1118472..1118726 (-)
• Length: 85 a.a.

Antitoxin (Protein)

• Gene name: yefM
• Uniprot ID: -
• Locus tag: PGR6_RS04810
• Protein ID: WP_064616224.1
• Coordinates: 1118723..1118977 (-)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
PGR6_RS04785	1114461..1115177	+	717	WP_064616221.1	peptide-methionine (S)-S-oxide reductase MsrA	-
PGR6_RS04790	1115193..1116206	-	1014	WP_064616222.1	sensor domain-containing diguanylate cyclase	-
PGR6_RS04795	1116282..1117187	-	906	WP_026286730.1	LysR family transcriptional regulator	-
PGR6_RS04800	1117290..1118465	+	1176	WP_019651780.1	aspartate aminotransferase family protein	-
PGR6_RS04805	1118472..1118726	-	255	WP_064616223.1	Txe/YoeB family addiction module toxin	Toxin
PGR6_RS04810	1118723..1118977	-	255	WP_064616224.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
PGR6_RS04815	1119205..1119732	-	528	WP_018930170.1	adenylate kinase	-
PGR6_RS04820	1119749..1121686	-	1938	WP_064616225.1	alkaline phosphatase family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (5-84)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-71)

Sequences

Toxin

Protein

• Length: 85 a.a.
• Molecular weight: 9898.39 Da
• Isoelectric Point: 8.0472

>T54536 WP_064616223.1 NZ_CP011567:c1118726-1118472 [Pseudomonas sp. GR 6-02]
MNIEFTPEGSDDYLWFQQNDKAGLKRINLLIKAILREPFEGLGKPEPLKHNLSGLWSRRITSEHRLVYAIENGEVRIVLC
RYHY

Nucleotide

• Length: 255 bp

>T54536 NZ_CP011567:c1118726-1118472 [Pseudomonas sp. GR 6-02]
ATGAATATCGAGTTCACTCCTGAAGGCTCGGACGACTATTTGTGGTTTCAGCAAAACGATAAGGCCGGGCTCAAACGAAT
CAACCTGCTGATCAAGGCGATCCTGCGTGAGCCCTTCGAAGGATTGGGCAAACCTGAACCGCTCAAACACAATCTGAGCG
GCCTCTGGTCACGCCGAATCACCTCCGAGCATCGCCTGGTTTATGCAATCGAGAATGGTGAGGTGCGCATCGTGCTTTGC
AGGTATCACTACTGA

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 9530.96 Da
• Isoelectric Point: 8.5163

>AT54536 WP_064616224.1 NZ_CP011567:c1118977-1118723 [Pseudomonas sp. GR 6-02]
MQTINYTTARAHLAETMDRVNEDRTPLLVTRQKGEPVVMMSLAEYNALEETAYLLRSPANAERLIKSIGNLRAGKTKVRQ
LIEE

Nucleotide

• Length: 255 bp

>AT54536 NZ_CP011567:c1118977-1118723 [Pseudomonas sp. GR 6-02]
ATGCAAACCATCAACTACACCACCGCACGTGCACATCTGGCCGAAACCATGGATCGGGTCAACGAAGACCGCACCCCATT
GCTGGTTACCCGCCAGAAAGGCGAACCTGTGGTGATGATGTCTCTGGCGGAGTACAACGCTCTCGAAGAGACAGCCTATC
TGCTCCGTTCTCCAGCCAATGCCGAGCGACTGATCAAATCAATCGGTAACCTGCGAGCAGGGAAGACCAAAGTCAGGCAA
CTTATCGAAGAATGA