Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relE-yefM/YoeB-YefM |
Location | 5252459..5252964 | Replicon | chromosome |
Accession | NZ_CP011566 | ||
Organism | Pseudomonas sp. DR 5-09 |
Toxin (Protein)
Gene name | relE | Uniprot ID | Q3K782 |
Locus tag | PDR5_RS23560 | Protein ID | WP_011335833.1 |
Coordinates | 5252710..5252964 (+) | Length | 85 a.a. |
Antitoxin (Protein)
Gene name | yefM | Uniprot ID | A0A0C2A0X2 |
Locus tag | PDR5_RS23555 | Protein ID | WP_039765667.1 |
Coordinates | 5252459..5252713 (+) | Length | 85 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
PDR5_RS23530 | 5247792..5248157 | + | 366 | WP_064599253.1 | hypothetical protein | - |
PDR5_RS23535 | 5248182..5248928 | - | 747 | WP_064599255.1 | hypothetical protein | - |
PDR5_RS23540 | 5249048..5249401 | + | 354 | WP_082934444.1 | hypothetical protein | - |
PDR5_RS23545 | 5249522..5250268 | + | 747 | WP_064599258.1 | hypothetical protein | - |
PDR5_RS23550 | 5250340..5252259 | + | 1920 | WP_064599260.1 | alkaline phosphatase family protein | - |
PDR5_RS23555 | 5252459..5252713 | + | 255 | WP_039765667.1 | type II toxin-antitoxin system prevent-host-death family antitoxin | Antitoxin |
PDR5_RS23560 | 5252710..5252964 | + | 255 | WP_011335833.1 | Txe/YoeB family addiction module toxin | Toxin |
PDR5_RS23565 | 5252973..5254145 | - | 1173 | WP_064599262.1 | aspartate aminotransferase family protein | - |
PDR5_RS23570 | 5254248..5255153 | + | 906 | WP_064599264.1 | LysR family transcriptional regulator | - |
PDR5_RS23575 | 5255207..5255611 | + | 405 | WP_064599267.1 | GNAT family N-acetyltransferase | - |
PDR5_RS23580 | 5255676..5256200 | + | 525 | WP_064599269.1 | hypothetical protein | - |
PDR5_RS23585 | 5256374..5257078 | + | 705 | WP_039765656.1 | hypothetical protein | - |
PDR5_RS23590 | 5257149..5257640 | - | 492 | WP_064599271.1 | RidA family protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 85 a.a. Molecular weight: 9950.59 Da Isoelectric Point: 9.6300
>T54534 WP_011335833.1 NZ_CP011566:5252710-5252964 [Pseudomonas sp. DR 5-09]
MKIQFTPTGWEDYLWFQQNDKAGLKRINLLIKAIQRQPFEGLGKPEPLKHNMSGFWSRRITAEHRLVYAIVDGEICVITC
RFHY
MKIQFTPTGWEDYLWFQQNDKAGLKRINLLIKAIQRQPFEGLGKPEPLKHNMSGFWSRRITAEHRLVYAIVDGEICVITC
RFHY
Download Length: 255 bp
>T54534 NZ_CP011566:5252710-5252964 [Pseudomonas sp. DR 5-09]
ATGAAAATCCAGTTCACGCCAACGGGCTGGGAAGACTACTTATGGTTTCAACAAAACGATAAGGCCGGTCTCAAACGAAT
CAATCTTTTGATCAAAGCGATCCAGCGCCAACCCTTTGAAGGCTTGGGTAAACCGGAGCCGCTCAAGCACAACATGAGCG
GCTTCTGGTCACGGCGGATAACTGCCGAGCATCGCTTGGTCTATGCGATCGTAGACGGCGAAATCTGCGTCATAACTTGC
AGATTTCACTACTGA
ATGAAAATCCAGTTCACGCCAACGGGCTGGGAAGACTACTTATGGTTTCAACAAAACGATAAGGCCGGTCTCAAACGAAT
CAATCTTTTGATCAAAGCGATCCAGCGCCAACCCTTTGAAGGCTTGGGTAAACCGGAGCCGCTCAAGCACAACATGAGCG
GCTTCTGGTCACGGCGGATAACTGCCGAGCATCGCTTGGTCTATGCGATCGTAGACGGCGAAATCTGCGTCATAACTTGC
AGATTTCACTACTGA
Antitoxin
Download Length: 85 a.a. Molecular weight: 9437.87 Da Isoelectric Point: 5.1314
>AT54534 WP_039765667.1 NZ_CP011566:5252459-5252713 [Pseudomonas sp. DR 5-09]
MDTINYTTARAHLAETMDRVNEDCAPLLVTRQKGEPVVMMSLAEYNALEETAYLLRSPANAERLIKSIGEMRAGKAKVRQ
LIEE
MDTINYTTARAHLAETMDRVNEDCAPLLVTRQKGEPVVMMSLAEYNALEETAYLLRSPANAERLIKSIGEMRAGKAKVRQ
LIEE
Download Length: 255 bp
>AT54534 NZ_CP011566:5252459-5252713 [Pseudomonas sp. DR 5-09]
ATGGACACTATCAACTACACCACAGCTCGTGCGCACTTGGCCGAAACCATGGATCGCGTGAATGAAGACTGCGCCCCGCT
TCTGGTAACCCGCCAAAAAGGCGAGCCTGTAGTGATGATGTCTCTGGCCGAATACAACGCGCTGGAAGAAACGGCTTATC
TGCTGCGTTCTCCGGCCAATGCCGAGCGCTTGATCAAATCGATTGGCGAAATGCGCGCTGGAAAAGCCAAAGTCAGGCAA
CTGATTGAAGAATGA
ATGGACACTATCAACTACACCACAGCTCGTGCGCACTTGGCCGAAACCATGGATCGCGTGAATGAAGACTGCGCCCCGCT
TCTGGTAACCCGCCAAAAAGGCGAGCCTGTAGTGATGATGTCTCTGGCCGAATACAACGCGCTGGAAGAAACGGCTTATC
TGCTGCGTTCTCCGGCCAATGCCGAGCGCTTGATCAAATCGATTGGCGAAATGCGCGCTGGAAAAGCCAAAGTCAGGCAA
CTGATTGAAGAATGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | Q3K782 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A0C2A0X2 |