Detailed information of TA system TA054494

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relB-parE/ParE-RHH
• Location: 2903350..2903906
• Replicon: chromosome
• Accession: NZ_CP011532
• Organism: Xanthomonas oryzae pv. oryzae strain XF89b

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: ABM06_RS14235
• Protein ID: WP_027703932.1
• Coordinates: 2903350..2903640 (-)
• Length: 97 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A854CIX2
• Locus tag: ABM06_RS14240
• Protein ID: WP_011408759.1
• Coordinates: 2903628..2903906 (-)
• Length: 93 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ABM06_RS14190	2899120..2900211	+	1092	WP_041182166.1	ribonuclease D	-
ABM06_RS14195	2900287..2900624	-	338	Protein_2592	ATP-dependent DNA ligase	-
ABM06_RS25495	2900684..2900890	-	207	Protein_2593	hypothetical protein	-
ABM06_RS14205	2900906..2901082	-	177	Protein_2594	DUF3606 domain-containing protein	-
ABM06_RS14210	2901304..2901705	+	402	WP_011259345.1	H-NS histone family protein	-
ABM06_RS14220	2902030..2902234	-	205	Protein_2596	kfra protein	-
ABM06_RS14225	2902569..2902748	-	180	WP_015463309.1	hypothetical protein	-
ABM06_RS14230	2903019..2903347	-	329	Protein_2598	hypothetical protein	-
ABM06_RS14235	2903350..2903640	-	291	WP_027703932.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
ABM06_RS14240	2903628..2903906	-	279	WP_011408759.1	CopG family ribbon-helix-helix protein	Antitoxin
ABM06_RS14245	2903987..2904419	-	433	Protein_2601	relaxase	-
ABM06_RS14250	2904391..2904591	-	201	WP_027703931.1	ribbon-helix-helix protein, CopG family	-
ABM06_RS14255	2905352..2906536	-	1185	WP_011408760.1	IS256 family transposase	-
ABM06_RS14260	2907117..2908082	+	966	WP_109181928.1	IS1595-like element ISXo5 family transposase	-
ABM06_RS14265	2908184..2908789	+	606	Protein_2605	DNA-3-methyladenine glycosylase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-94)

Antitoxin

• Ribbon-helix-helix protein, CopG (5-42)

Sequences

Toxin

Protein

• Length: 97 a.a.
• Molecular weight: 10915.48 Da
• Isoelectric Point: 9.5554

>T54494 WP_027703932.1 NZ_CP011532:c2903640-2903350 [Xanthomonas oryzae pv. oryzae]
MPQVIFAPAAIGDMLRLREFLRPKNPDAARRAGEAIRRGVQALGAHPRMGRLIEDLSEQYREWLIDFGDSGYVARYRFDG
DTVTILAVRHQKEAGY

Nucleotide

• Length: 291 bp

>T54494 NZ_CP011532:c2903640-2903350 [Xanthomonas oryzae pv. oryzae]
ATGCCACAAGTAATCTTTGCGCCGGCGGCGATCGGGGACATGCTACGGCTGCGTGAATTCCTGAGGCCGAAGAATCCCGA
TGCCGCGAGGCGGGCCGGCGAAGCGATTAGGCGCGGCGTCCAGGCTCTCGGTGCCCACCCTCGAATGGGGCGGCTCATAG
AAGATCTGTCTGAACAGTATCGGGAGTGGCTTATCGATTTTGGGGATAGCGGCTATGTGGCTCGGTACCGCTTCGATGGG
GATACCGTCACGATTTTGGCCGTGCGACACCAGAAGGAAGCGGGGTACTGA

Antitoxin

Protein

• Length: 93 a.a.
• Molecular weight: 10826.11 Da
• Isoelectric Point: 4.9736

>AT54494 WP_011408759.1 NZ_CP011532:c2903906-2903628 [Xanthomonas oryzae pv. oryzae]
MVTATSIKLDDELKGRVQHLAESRRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK

Nucleotide

• Length: 279 bp

>AT54494 NZ_CP011532:c2903906-2903628 [Xanthomonas oryzae pv. oryzae]
ATGGTTACGGCAACTTCCATCAAGCTTGATGATGAATTGAAAGGGCGGGTTCAGCACTTGGCAGAGTCGCGCCGGCGTAC
CCCGCATTGGATCATGCGCGAAGCCATTGAGCAGTACGTCGAGCGCGAGGAAAAGCGCGAGGCGCTGAACCGGGACACGC
TCAAGGCATGGGATGAATTTCAGGCGACTGGCCTGCATGTGACCGCTGAGGAAGTGGACAAGTGGCTCGCTAGCTGGGGA
ACTGACGACGAACTGCCTCCGCCAGAATGCCACAAGTAA

Structures

Antitoxin

• AlphaFold DB: A0A854CIX2