Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /Acetyltransf_4(toxin)
Location 3912899..3914310 Replicon chromosome
Accession NZ_CP011508
Organism Pseudomonas mendocina strain NSYSU

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag PSMEN_RS17985 Protein ID WP_096825807.1
Coordinates 3913741..3914310 (-) Length 190 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag PSMEN_RS17980 Protein ID WP_148118799.1
Coordinates 3912899..3913738 (-) Length 280 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PSMEN_RS17965 3909816..3910721 - 906 WP_148118797.1 hypothetical protein -
PSMEN_RS17970 3910723..3911295 - 573 WP_003246031.1 LemA family protein -
PSMEN_RS17975 3911486..3912823 + 1338 WP_148118798.1 peptidase -
PSMEN_RS17980 3912899..3913738 - 840 WP_148118799.1 AraC family transcriptional regulator Antitoxin
PSMEN_RS17985 3913741..3914310 - 570 WP_096825807.1 GNAT family N-acetyltransferase Toxin
PSMEN_RS17990 3914511..3917999 + 3489 WP_148118800.1 hybrid sensor histidine kinase/response regulator -
PSMEN_RS17995 3918041..3918949 - 909 WP_192813295.1 MerR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(14-146)

Antitoxin

DNA binding HTH domain, AraC-type

(197-274)


Sequences

Toxin        


Download         Length: 190 a.a.        Molecular weight: 21341.51 Da        Isoelectric Point: 9.8676

>T54371 WP_096825807.1 NZ_CP011508:c3914310-3913741 [Pseudomonas mendocina]
MFKPQLVTLQRGALRLEPLADADIPALVALAEANRDELLYMSGTQRLDWYRSALAELREQRALPFAIRLGEQLVGTTRFG
DFMNSLPACEIGWTWLDRAQHGSGLNASIKYLMLKHAFDNWGMVRVQLKTAASNLRSQRAIEKLGAAREGLLRNHRRLAD
GRLDHTVLYSITDQEWPQVRAALEARFGG

Download         Length: 570 bp

>T54371 NZ_CP011508:c3914310-3913741 [Pseudomonas mendocina]
ATGTTCAAACCGCAATTGGTCACGCTGCAGCGAGGAGCCTTGCGCCTGGAGCCACTGGCCGATGCCGATATCCCGGCCCT
GGTCGCGCTGGCCGAGGCCAATCGTGACGAGCTGCTGTACATGAGCGGTACCCAGCGTCTGGACTGGTATCGCAGCGCGC
TGGCCGAACTGCGCGAGCAACGCGCGCTGCCATTCGCCATCCGTCTCGGCGAGCAATTGGTCGGCACCACTCGCTTCGGC
GATTTCATGAACAGCCTGCCGGCCTGCGAGATCGGCTGGACCTGGCTCGATCGCGCCCAGCATGGCAGCGGGCTGAACGC
CAGCATCAAGTACCTGATGCTCAAGCATGCCTTCGACAACTGGGGCATGGTCCGTGTGCAGCTGAAAACCGCCGCCAGCA
ACCTGCGCTCGCAACGCGCCATCGAGAAGCTGGGCGCCGCCCGCGAGGGCCTGCTGCGTAACCATCGCCGCCTGGCCGAC
GGCCGTCTCGACCACACGGTGCTGTACAGCATCACCGATCAGGAATGGCCGCAGGTGCGCGCCGCCCTGGAAGCGCGCTT
CGGCGGCTGA

Antitoxin


Download         Length: 280 a.a.        Molecular weight: 30945.13 Da        Isoelectric Point: 7.3932

>AT54371 WP_148118799.1 NZ_CP011508:c3913738-3912899 [Pseudomonas mendocina]
MQPLTGSERARFSASDDLYGLELLSARFVEHRFAPHVHDGHVIAVLEAGAERYRYRGVDHLAGAGSIALLNPDEVHTGSK
GVEQGWQYRVFYPQPGTFEALLAELESLPAAPPMFHDSVHHDPLLASRLSALHCLLEDPHSEALQRQTLWREAMLELLQR
YARLPAPRGVGQEPRAVALAKELLASQLSEPPSLEELAAAVNLSPFHFARVFRRATGLPPHAWLRQRRLEQARTLLRSGC
SALSVAMQLGFADQSHLSRQFKQTYGVSPGEYRSAVARG

Download         Length: 840 bp

>AT54371 NZ_CP011508:c3913738-3912899 [Pseudomonas mendocina]
ATGCAGCCACTGACGGGAAGCGAACGCGCGCGGTTCAGCGCCAGCGACGATCTGTACGGCTTGGAGCTGTTGTCCGCACG
CTTTGTCGAACACCGTTTCGCCCCGCACGTGCACGACGGCCATGTGATCGCCGTGCTCGAAGCTGGTGCTGAGCGCTATC
GCTATCGCGGTGTCGATCACCTGGCGGGCGCCGGCAGCATCGCCTTGCTCAATCCGGACGAGGTGCATACCGGTTCCAAA
GGGGTCGAGCAAGGCTGGCAGTACCGGGTGTTCTACCCGCAGCCCGGTACATTCGAGGCGCTGCTGGCCGAACTCGAGTC
GCTACCGGCTGCACCGCCGATGTTCCACGACAGCGTGCACCATGATCCGCTCCTAGCGTCGCGGCTGAGTGCGCTGCACT
GTCTGCTGGAGGATCCGCACAGCGAGGCGCTGCAACGTCAGACCCTGTGGCGCGAGGCGATGCTCGAGCTGCTGCAGCGT
TACGCGCGCCTGCCGGCGCCGCGTGGCGTCGGCCAGGAACCGCGGGCGGTGGCGTTGGCCAAGGAGCTGCTTGCCAGCCA
GCTGAGCGAGCCGCCATCGCTGGAAGAGCTGGCGGCAGCGGTCAATCTCTCACCCTTTCACTTCGCCCGGGTGTTCCGCC
GGGCCACCGGTCTGCCACCGCATGCCTGGCTCAGGCAGCGTCGTCTGGAGCAGGCGCGGACGCTGCTCAGAAGTGGCTGC
TCGGCGCTCAGCGTCGCCATGCAACTGGGGTTCGCCGACCAGAGCCATTTGTCGCGGCAGTTCAAGCAGACCTATGGCGT
CAGCCCCGGCGAATACCGCAGCGCGGTGGCGCGAGGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References