Detailed information of TA system TA054287

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /BrnT(toxin)
• Location: 1766030..1766549
• Replicon: chromosome
• Accession: NZ_CP011477
• Organism: Spongiibacter sp. IMCC21906

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: IMCC21906_RS08070
• Protein ID: WP_047011741.1
• Coordinates: 1766030..1766293 (+)
• Length: 88 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: A0A0F7M2M1
• Locus tag: IMCC21906_RS08075
• Protein ID: WP_047011742.1
• Coordinates: 1766283..1766549 (+)
• Length: 89 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
IMCC21906_RS08050	1762036..1762911	+	876	WP_082117410.1	DUF547 domain-containing protein	-
IMCC21906_RS08055	1762895..1763659	+	765	WP_082117411.1	TIGR04283 family arsenosugar biosynthesis glycosyltransferase	-
IMCC21906_RS08060	1763656..1764282	+	627	WP_047011739.1	TIGR04282 family arsenosugar biosynthesis glycosyltransferase	-
IMCC21906_RS08065	1764530..1765717	-	1188	WP_047011740.1	NO-inducible flavohemoprotein	-
IMCC21906_RS08070	1766030..1766293	+	264	WP_047011741.1	BrnT family toxin	Toxin
IMCC21906_RS08075	1766283..1766549	+	267	WP_047011742.1	hypothetical protein	Antitoxin
IMCC21906_RS08080	1766738..1767145	+	408	WP_047011743.1	hypothetical protein	-
IMCC21906_RS08085	1767246..1767536	+	291	WP_047011744.1	hypothetical protein	-
IMCC21906_RS08090	1767799..1768929	-	1131	WP_047011745.1	spirocyclase AveC family protein	-
IMCC21906_RS08095	1769120..1770865	-	1746	WP_047011746.1	VWA domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Ribonuclease toxin, BrnT, of type II toxin-antitoxin system (6-81)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 88 a.a.
• Molecular weight: 10044.23 Da
• Isoelectric Point: 4.6413

>T54287 WP_047011741.1 NZ_CP011477:1766030-1766293 [Spongiibacter sp. IMCC21906]
MYSFEFDPKKSESNLEKHGIDFVDAQAIWQDSDFVEVMARSDDEPRTLVIGMIGGKHWSAIITYRSDTIRIISVRRSRDS
EVALYES

Nucleotide

• Length: 264 bp

>T54287 NZ_CP011477:1766030-1766293 [Spongiibacter sp. IMCC21906]
ATGTATTCATTCGAATTTGACCCGAAGAAGAGCGAATCTAACCTAGAAAAGCATGGTATTGACTTCGTTGATGCTCAGGC
TATCTGGCAAGATTCTGATTTTGTTGAAGTTATGGCTAGATCGGATGATGAACCAAGGACTTTGGTGATTGGCATGATCG
GCGGGAAGCATTGGTCAGCAATTATTACTTACCGTTCGGACACGATTAGGATTATCTCCGTCAGGCGGTCCCGAGATTCT
GAGGTGGCACTGTATGAAAGCTAA

Antitoxin

Protein

• Length: 89 a.a.
• Molecular weight: 10255.68 Da
• Isoelectric Point: 10.4202

>AT54287 WP_047011742.1 NZ_CP011477:1766283-1766549 [Spongiibacter sp. IMCC21906]
MKAKSLDKKFDDNQSDIVDELDLSTIKRPNQAQKRVNVDFPTWMVESLDKEASRLGVTRQSIIKVWLAERLEQSTFNKQM
RSTQKTRG

Nucleotide

• Length: 267 bp

>AT54287 NZ_CP011477:1766283-1766549 [Spongiibacter sp. IMCC21906]
ATGAAAGCTAAATCACTGGATAAGAAATTCGACGATAACCAATCGGATATCGTCGATGAACTCGATCTATCAACCATTAA
GCGTCCTAATCAAGCGCAGAAGCGGGTCAACGTAGATTTTCCCACCTGGATGGTTGAGTCACTCGACAAAGAGGCTTCAC
GGCTGGGGGTTACACGTCAGTCTATTATCAAGGTGTGGCTTGCCGAACGTTTGGAGCAGTCAACTTTTAACAAGCAAATG
CGGTCGACGCAGAAAACGCGCGGCTGA

Structures

Antitoxin

• AlphaFold DB: A0A0F7M2M1