Detailed information of TA system TA054283

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/-
• Location: 5353576..5354023
• Replicon: chromosome
• Accession: NZ_CP011456
• Organism: Anabaena sp. WA102 isolate

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: AA650_RS23630
• Protein ID: WP_199924336.1
• Coordinates: 5353814..5354023 (+)
• Length: 70 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A0K2M5D0
• Locus tag: AA650_RS23625
• Protein ID: WP_053540893.1
• Coordinates: 5353576..5353824 (+)
• Length: 83 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
AA650_RS23600	5348980..5350113	-	1134	WP_053540889.1	HetZ-related protein 2	-
AA650_RS23605	5350813..5351160	-	348	WP_039199651.1	carbon dioxide-concentrating mechanism protein CcmK	-
AA650_RS23610	5351248..5351559	-	312	WP_053540890.1	carbon dioxide-concentrating mechanism protein CcmK	-
AA650_RS23615	5351703..5352590	+	888	WP_053540891.1	alpha/beta hydrolase	-
AA650_RS23620	5352948..5353253	+	306	WP_199924335.1	hypothetical protein	-
AA650_RS23625	5353576..5353824	+	249	WP_053540893.1	hypothetical protein	Antitoxin
AA650_RS23630	5353814..5354023	+	210	WP_199924336.1	hypothetical protein	Toxin
AA650_RS23635	5354373..5355857	-	1485	WP_053540894.1	restriction endonuclease	-
AA650_RS23640	5356055..5357401	+	1347	WP_053540895.1	ATPase domain-containing protein	-
AA650_RS23645	5357535..5358416	+	882	WP_053540896.1	aspartoacylase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, mRNA interferase HigB (22-93)

Antitoxin

• Cro/C1-type helix-turn-helix domain (85-138)

Sequences

Toxin

Protein

• Length: 70 a.a.
• Molecular weight: 8164.29 Da
• Isoelectric Point: 10.2682

>T54283 WP_199924336.1 NZ_CP011456:5353814-5354023 [Anabaena sp. WA102]
MQNDSFLINIDLTPEYQRNLKHLAKKYRNIRSDTQSFITQLQKGNLLGDRLTGFNEDVYIYKARVKNSK

Nucleotide

• Length: 210 bp

>T54283 NZ_CP011456:5353814-5354023 [Anabaena sp. WA102]
ATGCAGAATGATTCTTTTTTAATTAATATTGATTTAACTCCTGAATATCAGAGAAATTTAAAACATTTAGCCAAAAAATA
CCGAAATATTCGTTCTGATACTCAATCTTTCATTACACAATTGCAAAAAGGAAATTTATTAGGAGATAGATTAACTGGTT
TTAATGAAGATGTTTATATTTATAAAGCTAGAGTCAAAAATAGTAAGTAG

Antitoxin

Protein

• Length: 83 a.a.
• Molecular weight: 9134.46 Da
• Isoelectric Point: 4.0373

>AT54283 WP_053540893.1 NZ_CP011456:5353576-5353824 [Anabaena sp. WA102]
MKALEVTGKIQQGQLTLDYPLEVDGFNIVKVIILLPEADDIESDPDDTPIQEIKESLKTALQEAKAGKRIPLEKMWEGID
AE

Nucleotide

• Length: 249 bp

>AT54283 NZ_CP011456:5353576-5353824 [Anabaena sp. WA102]
ATGAAAGCCTTAGAAGTTACTGGAAAAATTCAACAGGGACAATTAACCTTAGATTATCCTTTAGAAGTTGATGGTTTTAA
TATTGTTAAGGTAATTATTCTCCTACCAGAAGCAGATGACATTGAATCTGATCCTGATGACACTCCAATTCAGGAAATAA
AAGAGAGTTTAAAAACAGCATTACAAGAAGCAAAAGCAGGAAAAAGAATCCCTTTAGAAAAAATGTGGGAAGGAATTGAT
GCAGAATGA

Structures

Antitoxin

• AlphaFold DB: A0A0K2M5D0