Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) phd-doc/HTH_IclR(antitoxin)
Location 4332236..4333979 Replicon chromosome
Accession NZ_CP011409
Organism Herbaspirillum hiltneri N3

Toxin (Protein)


Gene name doc Uniprot ID -
Locus tag F506_RS19635 Protein ID WP_053200214.1
Coordinates 4333080..4333979 (-) Length 300 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID -
Locus tag F506_RS19630 Protein ID WP_053200212.1
Coordinates 4332236..4333069 (-) Length 278 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
F506_RS19610 4327362..4328837 - 1476 WP_144424199.1 aldehyde dehydrogenase -
F506_RS19615 4328866..4329666 - 801 WP_053200208.1 aspartate dehydrogenase -
F506_RS19620 4329686..4331422 - 1737 WP_053200209.1 thiamine pyrophosphate-binding protein -
F506_RS19625 4331415..4332230 - 816 WP_053200211.1 SDR family oxidoreductase -
F506_RS19630 4332236..4333069 - 834 WP_053200212.1 IclR family transcriptional regulator Antitoxin
F506_RS19635 4333080..4333979 - 900 WP_053200214.1 alpha/beta hydrolase Toxin
F506_RS19640 4334002..4334541 - 540 WP_053200216.1 cupin domain-containing protein -
F506_RS19645 4334579..4335343 - 765 WP_053200218.1 SDR family oxidoreductase -
F506_RS19650 4335358..4336209 - 852 WP_053200220.1 ABC transporter permease -
F506_RS19655 4336210..4337220 - 1011 WP_053200222.1 ABC transporter substrate-binding protein -
F506_RS19660 4337390..4338175 - 786 WP_007882427.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Alpha/beta hydrolase fold-1

(50-286)

Antitoxin

Transcription regulator IclR, C-terminal

(138-259)


Sequences

Toxin        


Download         Length: 300 a.a.        Molecular weight: 31933.46 Da        Isoelectric Point: 7.0546

>T54198 WP_053200214.1 NZ_CP011409:c4333979-4333080 [Herbaspirillum hiltneri N3]
MTALASTSVTCAETLKDSLSLLEGRFAESTVDIGNGGIVSYRSCGRGPAIVLLHGISSGAASWLQCALRLEKDAQVIAWN
APGYGRSTALPQMQPSAADYAARLELFLEALGIGSCLLVGHSLGAMMAAAYVGRSYKRASRLLLVSPAQGYGSEARRERG
RQIAQERLDVLRTIGVEGMAERSPARMLSAQAGETERAWVRWNIQWLNPAGYTQAVHMLCGDALQAYAPNGMLGHVPAEI
YCGVGDVVTTADDSRELAWNLNLPFHLIDNAGHACYIEQPGAVAAAICRQLSGHLYKLS

Download         Length: 900 bp

>T54198 NZ_CP011409:c4333979-4333080 [Herbaspirillum hiltneri N3]
ATGACCGCGCTCGCCTCCACCTCCGTCACCTGCGCCGAAACGCTGAAGGACTCCCTGAGCCTGCTCGAGGGACGTTTCGC
GGAAAGCACCGTCGACATCGGCAACGGCGGCATCGTGTCCTATCGCTCGTGCGGACGCGGTCCGGCGATAGTGCTGCTGC
ACGGCATCAGCTCGGGTGCGGCCTCGTGGTTGCAATGCGCGCTGCGTCTGGAAAAAGACGCCCAGGTCATCGCCTGGAAC
GCGCCCGGCTACGGCCGCTCGACCGCACTGCCGCAGATGCAGCCGAGCGCCGCCGATTACGCCGCGCGTCTGGAACTGTT
CCTGGAAGCATTGGGCATCGGCAGCTGTCTGCTGGTCGGCCATTCGCTCGGCGCCATGATGGCGGCGGCCTACGTCGGCC
GCAGCTACAAGCGCGCCTCGCGCCTGCTGCTGGTCAGTCCGGCGCAAGGCTACGGCAGTGAAGCCAGGCGCGAACGCGGC
CGGCAGATTGCACAAGAACGTCTGGACGTCCTGCGCACCATCGGCGTCGAAGGCATGGCCGAGCGCAGCCCGGCGCGCAT
GCTGTCGGCGCAGGCCGGCGAAACCGAGCGCGCGTGGGTGCGTTGGAATATCCAGTGGCTCAATCCGGCCGGCTACACCC
AGGCGGTGCATATGCTGTGCGGCGACGCACTGCAGGCGTATGCGCCCAACGGCATGCTGGGCCACGTGCCGGCGGAGATA
TATTGCGGCGTCGGCGACGTGGTGACCACCGCCGACGACAGCCGTGAGCTGGCCTGGAATCTGAACTTGCCGTTCCATCT
GATCGACAATGCGGGCCACGCCTGCTACATCGAGCAGCCCGGAGCGGTTGCAGCAGCGATATGTCGCCAACTCAGCGGTC
ACCTTTATAAACTTTCCTAG

Antitoxin


Download         Length: 278 a.a.        Molecular weight: 31044.59 Da        Isoelectric Point: 5.9844

>AT54198 WP_053200212.1 NZ_CP011409:c4333069-4332236 [Herbaspirillum hiltneri N3]
MNKPVLPEDESQEKYLVPGLERGLRLLCEFSRQDKTLSAPELARRLDVPRSTVFRLLTTLERMGFVERNDGGRDYRLGMA
VLRLGFEYLASLELTEIGRPLLDRLRDEIGYSCNLVVRDGRSIVYVAKSVTQTAFASHVNVGTRLPAHATVLGRVLLEDL
TLAELRELYPEEHLEVFSSNTPKTVVELFDMVQNDKQRGYVLQEGFFETSISTIAAPVRDHSGKVVAAMGATIPSPHIDT
DQLDLIVVKVRDTAGELSRLLDHAPAKSGKVVNMWRE

Download         Length: 834 bp

>AT54198 NZ_CP011409:c4333069-4332236 [Herbaspirillum hiltneri N3]
ATGAACAAACCAGTGCTGCCAGAAGATGAATCGCAAGAGAAATACCTCGTTCCAGGCCTGGAACGCGGCTTGCGCCTGCT
GTGTGAATTCAGCCGCCAGGACAAGACCCTGTCGGCGCCGGAACTCGCGCGCCGCCTCGACGTGCCGCGTTCCACCGTGT
TCCGCCTGCTGACCACGCTCGAGCGCATGGGCTTCGTCGAGCGCAACGACGGCGGCCGCGACTACCGCCTCGGCATGGCC
GTGCTGCGTCTCGGCTTCGAATACCTGGCCTCGCTGGAACTGACCGAAATCGGCCGTCCGCTGCTCGATCGCCTGCGCGA
CGAAATCGGCTACTCATGCAACCTGGTGGTGCGCGACGGCCGTTCGATCGTGTACGTCGCCAAGTCGGTCACGCAAACCG
CCTTCGCCAGCCACGTCAACGTCGGCACCCGCCTCCCTGCACACGCCACCGTGCTCGGCCGCGTGCTGCTGGAAGACCTG
ACCCTGGCCGAACTGCGCGAGCTGTATCCGGAAGAACACCTGGAAGTCTTCTCCAGCAACACGCCCAAGACCGTGGTCGA
GTTGTTTGACATGGTGCAGAACGACAAGCAACGCGGTTACGTGCTGCAGGAAGGCTTCTTCGAAACCAGCATCTCCACCA
TTGCCGCACCGGTGCGCGACCACTCCGGCAAGGTGGTGGCCGCGATGGGCGCGACGATCCCGTCGCCGCACATCGACACC
GACCAGCTCGACCTGATCGTGGTCAAGGTGCGCGATACCGCCGGCGAACTGTCGCGCCTGCTTGACCATGCGCCGGCGAA
GTCGGGCAAGGTCGTCAACATGTGGCGGGAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References