Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-CC2985
Location 39519..40047 Replicon chromosome
Accession NZ_CP011409
Organism Herbaspirillum hiltneri N3

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag F506_RS00180 Protein ID WP_053194705.1
Coordinates 39519..39809 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag F506_RS00185 Protein ID WP_053194706.1
Coordinates 39802..40047 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
F506_RS00155 34852..35811 + 960 WP_053194700.1 ATP-binding cassette domain-containing protein -
F506_RS00160 35851..37476 + 1626 WP_053194701.1 gamma-glutamyltransferase family protein -
F506_RS00165 37509..38288 + 780 WP_053194702.1 GntR family transcriptional regulator -
F506_RS00170 38370..38882 + 513 WP_053194703.1 hypothetical protein -
F506_RS00175 38959..39489 + 531 WP_053194704.1 hypothetical protein -
F506_RS00180 39519..39809 - 291 WP_053194705.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
F506_RS00185 39802..40047 - 246 WP_053194706.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
F506_RS00190 40155..40523 - 369 WP_053194707.1 DUF3325 domain-containing protein -
F506_RS22940 40523..41293 - 771 WP_053194708.1 TonB-dependent receptor plug domain-containing protein -
F506_RS22945 41290..41523 - 234 WP_144423963.1 hypothetical protein -
F506_RS00200 41646..42350 + 705 WP_053194709.1 SDR family oxidoreductase -
F506_RS00205 42716..43489 + 774 WP_053194710.1 enoyl-CoA hydratase/isomerase family protein -
F506_RS00210 43598..44656 + 1059 WP_053194711.1 ABC transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin

Antitoxin ParD

(7-80)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11136.77 Da        Isoelectric Point: 8.0612

>T54196 WP_053194705.1 NZ_CP011409:c39809-39519 [Herbaspirillum hiltneri N3]
MAEYRLSPAAERDLEAVWTYTRLKWSAEQADRYTDILMAAFEELAQAPQAAPACDHIRPGYRRRSVGRHMIYFRVTAYGV
AIVRILHDLMDVSRHL

Download         Length: 291 bp

>T54196 NZ_CP011409:c39809-39519 [Herbaspirillum hiltneri N3]
ATGGCTGAATACCGTCTTAGTCCCGCCGCCGAGCGTGACCTCGAGGCGGTATGGACTTATACCCGCCTTAAGTGGAGCGC
AGAGCAGGCAGATCGTTACACCGACATCCTGATGGCGGCCTTTGAGGAGCTGGCACAGGCGCCACAAGCGGCGCCTGCAT
GTGACCATATTCGTCCGGGTTATCGTCGCCGCAGCGTGGGGCGACACATGATCTATTTCCGTGTGACCGCCTATGGCGTG
GCAATCGTCCGGATACTGCACGATCTGATGGATGTCTCCCGACATCTCTGA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9280.34 Da        Isoelectric Point: 6.4710

>AT54196 WP_053194706.1 NZ_CP011409:c40047-39802 [Herbaspirillum hiltneri N3]
MGTVRKTITLTDKQDSWIKSQIEAGHYTNDSEYIRDLIRREQERSIEVETIRAALIEGESSGEPRPFDAAAFKQRMSARH
G

Download         Length: 246 bp

>AT54196 NZ_CP011409:c40047-39802 [Herbaspirillum hiltneri N3]
ATGGGAACCGTGCGCAAAACCATTACGTTGACGGACAAACAGGATAGCTGGATCAAGTCGCAGATTGAGGCCGGTCACTA
CACGAATGACAGCGAATACATCCGTGATCTGATCCGACGCGAACAAGAACGCAGCATTGAAGTTGAGACTATCCGGGCTG
CCTTGATCGAGGGTGAATCCAGCGGAGAACCCCGCCCCTTCGACGCCGCCGCATTCAAGCAGAGAATGTCAGCCAGGCAT
GGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References