Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hipBA/HipA-couple_hipB
Location 15791..17478 Replicon chromosome
Accession NZ_CP011409
Organism Herbaspirillum hiltneri N3

Toxin (Protein)


Gene name hipA Uniprot ID -
Locus tag F506_RS00070 Protein ID WP_016836215.1
Coordinates 16135..17478 (+) Length 448 a.a.

Antitoxin (Protein)


Gene name hipB Uniprot ID -
Locus tag F506_RS22455 Protein ID WP_083458183.1
Coordinates 15791..16132 (+) Length 114 a.a.

Genomic Context

F506_RS00045F506_RS00050F506_RS00055F506_RS00060F506_RS22455F506_RS00070F506_RS00090F506_RS00035F506_RS00040F506_RS00075F506_RS00080F506_RS00085F506_RS00095
Location: 12487..13425 (939 bp)
Type: Others
Protein ID: WP_053194685.1
Location: 13485..14405 (921 bp)
Type: Others
Protein ID: WP_053194686.1
Location: 14688..15449 (762 bp)
Type: Others
Protein ID: WP_053194687.1
Location: 15486..15680 (195 bp)
Type: Others
Protein ID: WP_016836213.1
Location: 15791..16132 (342 bp)
Type: Antitoxin
Protein ID: WP_083458183.1
Location: 16135..17478 (1344 bp)
Type: Toxin
Protein ID: WP_016836215.1
Location: 19180..20265 (1086 bp)
Type: Others
Protein ID: WP_144423961.1
Location: 10999..11625 (627 bp)
Type: Others
Protein ID: WP_053194683.1
Location: 11703..12218 (516 bp)
Type: Others
Protein ID: WP_053194684.1
Location: 17480..17797 (318 bp)
Type: Others
Protein ID: WP_053194688.1
Location: 17837..18202 (366 bp)
Type: Others
Protein ID: WP_053194689.1
Location: 18286..18870 (585 bp)
Type: Others
Protein ID: WP_053201085.1
Location: 20279..22132 (1854 bp)
Type: Others
Protein ID: WP_053194690.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
F506_RS0003510999..11625-627WP_053194683.1ATP-binding cassette domain-containing protein-
F506_RS0004011703..12218-516WP_053194684.1DUF421 domain-containing protein-
F506_RS0004512487..13425+939WP_053194685.1LysR family transcriptional regulator-
F506_RS0005013485..14405+921WP_053194686.1ornithine cyclodeaminase family protein-
F506_RS0005514688..15449+762WP_053194687.1SDR family oxidoreductase-
F506_RS0006015486..15680+195WP_016836213.1hypothetical protein-
F506_RS2245515791..16132+342WP_083458183.1helix-turn-helix domain-containing proteinAntitoxin
F506_RS0007016135..17478+1344WP_016836215.1type II toxin-antitoxin system HipA family toxinToxin
F506_RS0007517480..17797-318WP_053194688.1ferredoxin family protein-
F506_RS0008017837..18202-366WP_053194689.1hypothetical protein-
F506_RS0008518286..18870-585WP_053201085.1sigma-70 family RNA polymerase sigma factor-
F506_RS0009019180..20265+1086WP_144423961.1sensor domain-containing diguanylate cyclase-
F506_RS0009520279..22132-1854WP_053194690.1peptide transporter-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA, N-terminal subdomain 1

(10-110)

Antitoxin

Cro/C1-type helix-turn-helix domain

(14-67)


Sequences

Toxin        


Download         Length: 448 a.a.        Molecular weight: 49403.15 Da        Isoelectric Point: 6.2878

>T54195 WP_016836215.1 NZ_CP011409:16135-17478 [Herbaspirillum hiltneri N3]
MGRRTLTQRLFVWMNGIRVAAWDKTRDEERLSYFPEWQEQEEGRPLSLSLPFTPNNLVYRGALVSSFFDNLLPDNDAIRR
RLAQRYHAENTDPFSLLAELGRDCVGAIQLLPPDVAPTDLFSISGRPLDEAEVANLLRNTTSAAILGQTGEHDDLRLSIA
GAQEKTALLYHEGAWHLPQGSTPTTHIFKLPLGLVGNRRADMQSSVENEWLCSKLMAAYELPIAHCDIGRFEDQKVLIVE
RFDRKPASDGSWIIRLPQEDMCQATGTPSLRKYQADGGPGIADVIHVLDRSDKAQQDKRNFFKTQIVFWLLAATDGHAKN
FSIAHLPGGSYCATPLYDVLSAHPITGPGPNQMAAQRLKLAMAVRSTSNYYLIDRIQRRHWGAQAAQVGLGAAAAEEIIE
EVIAATDGVLDAVGRQLPEDFPAKLADVIFSGVARQCKRLAAMPAGV

Download         Length: 1344 bp

>T54195 NZ_CP011409:16135-17478 [Herbaspirillum hiltneri N3]
ATGGGTCGCCGTACGCTGACGCAACGACTCTTCGTCTGGATGAATGGCATTCGCGTGGCTGCCTGGGACAAGACCCGGGA
CGAGGAACGCCTGAGCTATTTCCCAGAGTGGCAGGAGCAGGAGGAAGGACGGCCCCTGTCGCTCTCGCTGCCGTTCACGC
CAAATAACTTGGTCTACCGCGGCGCGCTTGTTTCTTCCTTCTTCGACAATCTCTTGCCGGACAACGATGCGATTCGCCGT
CGTCTGGCGCAGCGTTATCACGCAGAAAATACCGATCCATTTTCTTTGCTGGCAGAACTCGGCCGCGATTGTGTCGGCGC
CATTCAGCTCTTGCCCCCGGACGTAGCGCCGACGGATTTGTTTTCCATTTCCGGCAGACCTCTGGACGAGGCGGAAGTCG
CGAATCTCCTGCGCAACACCACGAGCGCCGCGATTCTCGGACAGACCGGCGAGCACGACGATCTGCGCCTGTCCATCGCT
GGCGCGCAGGAAAAGACTGCGCTGCTTTATCACGAGGGCGCATGGCATTTGCCGCAAGGGAGTACGCCGACCACACACAT
CTTCAAACTGCCGCTGGGACTGGTCGGCAACCGGCGCGCCGACATGCAGAGCTCGGTCGAGAACGAATGGCTGTGTTCAA
AACTGATGGCCGCATATGAATTGCCGATCGCTCATTGCGACATCGGCCGTTTCGAAGATCAGAAGGTGCTGATCGTCGAG
CGTTTTGATCGCAAGCCGGCGAGTGATGGCAGCTGGATCATTCGCCTGCCGCAGGAAGACATGTGCCAGGCAACGGGAAC
GCCGTCCCTGCGCAAATATCAGGCGGATGGCGGCCCCGGCATTGCCGACGTCATCCATGTGCTTGACAGGTCGGATAAGG
CGCAGCAGGACAAGCGCAATTTTTTCAAGACGCAGATCGTGTTCTGGTTGCTGGCGGCGACCGACGGCCATGCCAAGAAT
TTCAGCATCGCCCATCTGCCCGGGGGGAGTTATTGCGCCACGCCTTTGTACGATGTTTTGTCGGCGCATCCGATCACCGG
TCCGGGGCCGAACCAGATGGCGGCACAGCGTCTGAAGCTGGCGATGGCTGTGCGCAGCACCAGCAACTACTATCTGATCG
ACAGAATCCAGCGCCGCCATTGGGGCGCGCAAGCAGCCCAGGTGGGACTCGGCGCTGCGGCGGCCGAAGAGATCATTGAA
GAAGTCATCGCGGCGACTGACGGCGTGCTTGATGCAGTCGGCAGGCAATTGCCAGAAGATTTTCCTGCCAAGCTGGCGGA
CGTAATCTTCAGCGGCGTCGCCCGTCAGTGCAAGCGACTCGCCGCCATGCCTGCAGGCGTCTGA

Antitoxin


Download         Length: 114 a.a.        Molecular weight: 12377.46 Da        Isoelectric Point: 11.0197

>AT54195 WP_083458183.1 NZ_CP011409:15791-16132 [Herbaspirillum hiltneri N3]
MLYPIKTLSQLRPILQGFRKEAGLTQAALAERLGMSQQNYAKLEANPASVSMERLHAVFSVLNVEMALSQAGTAVTVTTS
PAVPTRKPTLKTTTKEPQSLRRVTSPAIKKEVW

Download         Length: 342 bp

>AT54195 NZ_CP011409:15791-16132 [Herbaspirillum hiltneri N3]
ATGCTCTATCCCATCAAAACCCTCAGTCAGCTTCGGCCGATCCTGCAAGGCTTTCGCAAGGAAGCAGGACTGACCCAAGC
GGCGCTGGCGGAGCGCTTGGGCATGTCCCAGCAGAATTATGCCAAGCTCGAAGCCAATCCGGCCTCGGTCAGCATGGAGC
GTCTTCACGCTGTATTCAGCGTACTGAACGTGGAGATGGCGTTAAGCCAGGCAGGAACTGCCGTCACGGTAACCACTTCG
CCCGCAGTGCCAACGCGCAAACCTACACTCAAGACAACAACAAAAGAGCCGCAATCCCTGCGCCGCGTCACTTCGCCAGC
CATTAAAAAAGAGGTCTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References