Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) phd-doc/Doc(toxin)
Location 513290..513864 Replicon chromosome
Accession NZ_CP011378
Organism Moraxella bovoculi strain 28389

Toxin (Protein)


Gene name doc Uniprot ID -
Locus tag AAX07_RS02510 Protein ID WP_046696178.1
Coordinates 513290..513694 (-) Length 135 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID -
Locus tag AAX07_RS02515 Protein ID WP_046696179.1
Coordinates 513694..513864 (-) Length 57 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AAX07_RS02495 508440..510830 - 2391 WP_046699358.1 PBP1A family penicillin-binding protein -
AAX07_RS11750 511314..511721 + 408 WP_155399971.1 hypothetical protein -
AAX07_RS11755 511810..512055 + 246 WP_080946089.1 hypothetical protein -
AAX07_RS02505 512118..513284 - 1167 WP_046696177.1 2-methylaconitate cis-trans isomerase PrpF -
AAX07_RS02510 513290..513694 - 405 WP_046696178.1 type II toxin-antitoxin system death-on-curing family toxin Toxin
AAX07_RS02515 513694..513864 - 171 WP_046696179.1 hypothetical protein Antitoxin
AAX07_RS02520 513958..514674 - 717 WP_046696180.1 hypothetical protein -
AAX07_RS02525 514741..517323 - 2583 WP_046696181.1 Fe/S-dependent 2-methylisocitrate dehydratase AcnD -
AAX07_RS02530 517537..517995 - 459 WP_046696182.1 DMT family transporter -
AAX07_RS02535 517992..518285 - 294 WP_046696183.1 DUF3865 domain-containing protein -
AAX07_RS02540 518321..518698 - 378 WP_046696184.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Death on curing protein

(9-120)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 14966.03 Da        Isoelectric Point: 4.2429

>T54177 WP_046696178.1 NZ_CP011378:c513694-513290 [Moraxella bovoculi]
MEIICFPFERVIEINTYILSTEKGMKGQADIGKLQGALSRIDNAILYEGLNDVFEIASKYANSIAMAHALSDANKRTGLA
VALEYLSLNDYEITIDHILMADAMRDLVIGELSESEFADILYHQYISSTNPQKE

Download         Length: 405 bp

>T54177 NZ_CP011378:c513694-513290 [Moraxella bovoculi]
ATGGAAATTATTTGTTTTCCATTTGAACGGGTCATTGAAATTAATACCTACATTCTTTCTACCGAAAAAGGAATGAAAGG
ACAAGCGGATATTGGCAAATTACAAGGGGCATTATCTCGGATTGATAATGCGATTTTGTATGAAGGCTTAAATGATGTTT
TTGAAATTGCCAGTAAATACGCAAATAGCATTGCAATGGCTCACGCCTTATCTGATGCCAATAAACGCACAGGGTTGGCG
GTTGCCCTAGAATATTTATCGCTCAATGATTATGAAATTACGATAGACCATATTTTAATGGCGGATGCAATGCGTGATTT
GGTCATTGGCGAATTGTCCGAAAGTGAATTTGCGGATATTTTATATCATCAATATATAAGTAGCACAAACCCACAAAAGG
AATAA

Antitoxin


Download         Length: 57 a.a.        Molecular weight: 6424.53 Da        Isoelectric Point: 10.9086

>AT54177 WP_046696179.1 NZ_CP011378:c513864-513694 [Moraxella bovoculi]
MNNKLSKYGINPTNRPKIPATKKLDLTGEQGQQIIKSETKLVLRTHKETFKRLADM

Download         Length: 171 bp

>AT54177 NZ_CP011378:c513864-513694 [Moraxella bovoculi]
ATGAACAACAAACTTTCAAAATACGGCATTAACCCAACCAATCGCCCAAAAATCCCTGCAACCAAAAAGCTAGATTTAAC
AGGCGAACAAGGGCAACAGATTATTAAATCTGAAACAAAATTGGTTTTGCGAACCCATAAAGAAACCTTTAAACGCTTGG
CAGATATGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References