Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) phd-doc/Doc(toxin)
Location 508737..509311 Replicon chromosome
Accession NZ_CP011377
Organism Moraxella bovoculi strain 23343

Toxin (Protein)


Gene name doc Uniprot ID -
Locus tag AAX05_RS02470 Protein ID WP_046696178.1
Coordinates 508737..509141 (-) Length 135 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID -
Locus tag AAX05_RS02475 Protein ID WP_046696179.1
Coordinates 509141..509311 (-) Length 57 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AAX05_RS02455 503887..506277 - 2391 WP_046696176.1 PBP1A family penicillin-binding protein -
AAX05_RS10495 506761..507168 + 408 WP_155399971.1 hypothetical protein -
AAX05_RS10500 507257..507502 + 246 WP_080946089.1 hypothetical protein -
AAX05_RS02465 507565..508731 - 1167 WP_046696177.1 2-methylaconitate cis-trans isomerase PrpF -
AAX05_RS02470 508737..509141 - 405 WP_046696178.1 type II toxin-antitoxin system death-on-curing family toxin Toxin
AAX05_RS02475 509141..509311 - 171 WP_046696179.1 hypothetical protein Antitoxin
AAX05_RS02480 509406..510122 - 717 WP_046696180.1 hypothetical protein -
AAX05_RS02485 510189..512771 - 2583 WP_046696181.1 Fe/S-dependent 2-methylisocitrate dehydratase AcnD -
AAX05_RS02490 512985..513443 - 459 WP_046696182.1 DMT family transporter -
AAX05_RS02495 513440..513733 - 294 WP_046696183.1 DUF3865 domain-containing protein -
AAX05_RS02500 513769..514146 - 378 WP_046696184.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Death on curing protein

(9-120)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 14966.03 Da        Isoelectric Point: 4.2429

>T54174 WP_046696178.1 NZ_CP011377:c509141-508737 [Moraxella bovoculi]
MEIICFPFERVIEINTYILSTEKGMKGQADIGKLQGALSRIDNAILYEGLNDVFEIASKYANSIAMAHALSDANKRTGLA
VALEYLSLNDYEITIDHILMADAMRDLVIGELSESEFADILYHQYISSTNPQKE

Download         Length: 405 bp

>T54174 NZ_CP011377:c509141-508737 [Moraxella bovoculi]
ATGGAAATTATTTGTTTTCCATTTGAACGGGTCATTGAAATTAATACCTACATTCTTTCTACCGAAAAAGGAATGAAAGG
ACAAGCGGATATTGGCAAATTACAAGGGGCATTATCTCGGATTGATAATGCGATTTTGTATGAAGGCTTAAATGATGTTT
TTGAAATTGCCAGTAAATACGCAAATAGCATTGCAATGGCTCACGCCTTATCTGATGCCAATAAACGCACAGGGTTGGCG
GTTGCCCTAGAATATTTATCGCTCAATGATTATGAAATTACGATAGACCATATTTTAATGGCGGATGCAATGCGTGATTT
GGTCATTGGCGAATTGTCCGAAAGTGAATTTGCGGATATTTTATATCATCAATATATAAGTAGCACAAACCCACAAAAGG
AATAA

Antitoxin


Download         Length: 57 a.a.        Molecular weight: 6424.53 Da        Isoelectric Point: 10.9086

>AT54174 WP_046696179.1 NZ_CP011377:c509311-509141 [Moraxella bovoculi]
MNNKLSKYGINPTNRPKIPATKKLDLTGEQGQQIIKSETKLVLRTHKETFKRLADM

Download         Length: 171 bp

>AT54174 NZ_CP011377:c509311-509141 [Moraxella bovoculi]
ATGAACAACAAACTTTCAAAATACGGCATTAACCCAACCAATCGCCCAAAAATCCCTGCAACCAAAAAGCTAGATTTAAC
AGGCGAACAAGGGCAACAGATTATTAAATCTGAAACAAAATTGGTTTTGCGAACCCATAAAGAAACCTTTAAACGCTTGG
CAGATATGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References