Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) phd-doc/Doc(toxin)
Location 1834606..1835180 Replicon chromosome
Accession NZ_CP011376
Organism Moraxella bovoculi strain 22581

Toxin (Protein)


Gene name doc Uniprot ID -
Locus tag AAX06_RS08765 Protein ID WP_046696178.1
Coordinates 1834776..1835180 (+) Length 135 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID -
Locus tag AAX06_RS08760 Protein ID WP_046696179.1
Coordinates 1834606..1834776 (+) Length 57 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AAX06_RS08735 1829772..1830149 + 378 WP_046696184.1 hypothetical protein -
AAX06_RS08740 1830185..1830478 + 294 WP_046696183.1 DUF3865 domain-containing protein -
AAX06_RS08745 1830475..1830933 + 459 WP_046696182.1 DMT family transporter -
AAX06_RS08750 1831147..1833729 + 2583 WP_046696181.1 Fe/S-dependent 2-methylisocitrate dehydratase AcnD -
AAX06_RS08755 1833796..1834512 + 717 WP_046696180.1 hypothetical protein -
AAX06_RS08760 1834606..1834776 + 171 WP_046696179.1 hypothetical protein Antitoxin
AAX06_RS08765 1834776..1835180 + 405 WP_046696178.1 type II toxin-antitoxin system death-on-curing family toxin Toxin
AAX06_RS08770 1835186..1836352 + 1167 WP_046696177.1 2-methylaconitate cis-trans isomerase PrpF -
AAX06_RS11785 1836415..1836660 - 246 WP_080946089.1 hypothetical protein -
AAX06_RS11790 1836749..1837201 - 453 WP_155400187.1 hypothetical protein -
AAX06_RS08780 1837640..1840030 + 2391 WP_046699358.1 PBP1A family penicillin-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Death on curing protein

(9-120)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 14966.03 Da        Isoelectric Point: 4.2429

>T54173 WP_046696178.1 NZ_CP011376:1834776-1835180 [Moraxella bovoculi]
MEIICFPFERVIEINTYILSTEKGMKGQADIGKLQGALSRIDNAILYEGLNDVFEIASKYANSIAMAHALSDANKRTGLA
VALEYLSLNDYEITIDHILMADAMRDLVIGELSESEFADILYHQYISSTNPQKE

Download         Length: 405 bp

>T54173 NZ_CP011376:1834776-1835180 [Moraxella bovoculi]
ATGGAAATTATTTGTTTTCCATTTGAACGGGTCATTGAAATTAATACCTACATTCTTTCTACCGAAAAAGGAATGAAAGG
ACAAGCGGATATTGGCAAATTACAAGGGGCATTATCTCGGATTGATAATGCGATTTTGTATGAAGGCTTAAATGATGTTT
TTGAAATTGCCAGTAAATACGCAAATAGCATTGCAATGGCTCACGCCTTATCTGATGCCAATAAACGCACAGGGTTGGCG
GTTGCCCTAGAATATTTATCGCTCAATGATTATGAAATTACGATAGACCATATTTTAATGGCGGATGCAATGCGTGATTT
GGTCATTGGCGAATTGTCCGAAAGTGAATTTGCGGATATTTTATATCATCAATATATAAGTAGCACAAACCCACAAAAGG
AATAA

Antitoxin


Download         Length: 57 a.a.        Molecular weight: 6424.53 Da        Isoelectric Point: 10.9086

>AT54173 WP_046696179.1 NZ_CP011376:1834606-1834776 [Moraxella bovoculi]
MNNKLSKYGINPTNRPKIPATKKLDLTGEQGQQIIKSETKLVLRTHKETFKRLADM

Download         Length: 171 bp

>AT54173 NZ_CP011376:1834606-1834776 [Moraxella bovoculi]
ATGAACAACAAACTTTCAAAATACGGCATTAACCCAACCAATCGCCCAAAAATCCCTGCAACCAAAAAGCTAGATTTAAC
AGGCGAACAAGGGCAACAGATTATTAAATCTGAAACAAAATTGGTTTTGCGAACCCATAAAGAAACCTTTAAACGCTTGG
CAGATATGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References