Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relB-parE/ParE-RHH |
| Location | 257805..258373 | Replicon | chromosome |
| Accession | NZ_CP011371 | ||
| Organism | Caldimonas brevitalea strain DSM 7029 | ||
Toxin (Protein)
| Gene name | parE | Uniprot ID | - |
| Locus tag | AAW51_RS01135 | Protein ID | WP_047193154.1 |
| Coordinates | 258083..258373 (+) | Length | 97 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | A0A0G3BC78 |
| Locus tag | AAW51_RS01130 | Protein ID | WP_047193153.1 |
| Coordinates | 257805..258095 (+) | Length | 97 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| AAW51_RS01105 (AAW51_0221) | 252877..253332 | - | 456 | WP_047193148.1 | DUF2214 family protein | - |
| AAW51_RS01110 (AAW51_0222) | 253379..254302 | - | 924 | WP_047193149.1 | LysR family transcriptional regulator | - |
| AAW51_RS01115 (AAW51_0223) | 254538..255254 | + | 717 | WP_047193150.1 | haloacid dehalogenase type II | - |
| AAW51_RS01120 (AAW51_0224) | 255251..256006 | + | 756 | WP_047193151.1 | sulfite exporter TauE/SafE family protein | - |
| AAW51_RS01125 (AAW51_0225) | 256053..257633 | + | 1581 | WP_047193152.1 | malate synthase A | - |
| AAW51_RS01130 (AAW51_0226) | 257805..258095 | + | 291 | WP_047193153.1 | CopG family ribbon-helix-helix protein | Antitoxin |
| AAW51_RS01135 (AAW51_0227) | 258083..258373 | + | 291 | WP_047193154.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| AAW51_RS01140 (AAW51_0228) | 258481..259239 | + | 759 | WP_047193155.1 | class II glutamine amidotransferase | - |
| AAW51_RS01145 (AAW51_0229) | 259252..261180 | - | 1929 | WP_053013230.1 | sensor histidine kinase | - |
| AAW51_RS01150 (AAW51_0230) | 261146..261799 | - | 654 | WP_047193156.1 | response regulator transcription factor | - |
| AAW51_RS01155 (AAW51_0231) | 262060..262560 | + | 501 | WP_047193157.1 | (2Fe-2S)-binding protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 97 a.a. Molecular weight: 10904.52 Da Isoelectric Point: 7.2006
>T54171 WP_047193154.1 NZ_CP011371:258083-258373 [Caldimonas brevitalea]
MPEIRYAPAALRDLERLRTFLQSKAPDAAQRAGRAVAQALKVLGQQPHIGRPVEEMPIEYREWLIDFGDSGYVALYRIDG
DLVTILAVRHQREVGY
MPEIRYAPAALRDLERLRTFLQSKAPDAAQRAGRAVAQALKVLGQQPHIGRPVEEMPIEYREWLIDFGDSGYVALYRIDG
DLVTILAVRHQREVGY
Download Length: 291 bp
>T54171 NZ_CP011371:258083-258373 [Caldimonas brevitalea]
ATGCCGGAAATAAGATACGCACCCGCCGCCTTGCGTGACCTGGAGCGGCTGCGCACCTTCCTTCAATCGAAAGCGCCCGA
CGCTGCGCAACGAGCCGGTCGCGCCGTTGCCCAGGCCCTGAAGGTCCTCGGCCAGCAGCCCCACATTGGACGGCCGGTCG
AGGAGATGCCGATCGAGTACCGCGAATGGCTCATTGACTTCGGCGACAGCGGATATGTCGCGCTGTACCGCATCGACGGT
GACCTGGTCACCATCCTGGCCGTCCGCCACCAGCGCGAAGTCGGCTACTGA
ATGCCGGAAATAAGATACGCACCCGCCGCCTTGCGTGACCTGGAGCGGCTGCGCACCTTCCTTCAATCGAAAGCGCCCGA
CGCTGCGCAACGAGCCGGTCGCGCCGTTGCCCAGGCCCTGAAGGTCCTCGGCCAGCAGCCCCACATTGGACGGCCGGTCG
AGGAGATGCCGATCGAGTACCGCGAATGGCTCATTGACTTCGGCGACAGCGGATATGTCGCGCTGTACCGCATCGACGGT
GACCTGGTCACCATCCTGGCCGTCCGCCACCAGCGCGAAGTCGGCTACTGA
Antitoxin
Download Length: 97 a.a. Molecular weight: 11254.61 Da Isoelectric Point: 5.2761
>AT54171 WP_047193153.1 NZ_CP011371:257805-258095 [Caldimonas brevitalea]
MTTAGVRPVAVKIDDDLKERIQRLAQARARTPHWIMKEAISQYVEREEKHEAFRQAGLKAWEEYRATGQYARPEEVEAWL
ESWGTEDEQPAPECRK
MTTAGVRPVAVKIDDDLKERIQRLAQARARTPHWIMKEAISQYVEREEKHEAFRQAGLKAWEEYRATGQYARPEEVEAWL
ESWGTEDEQPAPECRK
Download Length: 291 bp
>AT54171 NZ_CP011371:257805-258095 [Caldimonas brevitalea]
ATGACCACGGCCGGCGTTCGCCCAGTTGCCGTCAAGATCGATGACGACCTCAAGGAGCGCATCCAACGCCTCGCTCAGGC
ACGTGCGCGCACGCCCCACTGGATCATGAAGGAGGCGATTTCCCAGTACGTCGAACGCGAGGAGAAACACGAGGCGTTCC
GGCAAGCCGGGCTCAAGGCGTGGGAGGAGTATCGGGCAACCGGCCAATACGCGCGCCCCGAGGAAGTCGAGGCATGGCTC
GAAAGCTGGGGCACCGAGGATGAACAGCCGGCACCGGAATGCCGGAAATAA
ATGACCACGGCCGGCGTTCGCCCAGTTGCCGTCAAGATCGATGACGACCTCAAGGAGCGCATCCAACGCCTCGCTCAGGC
ACGTGCGCGCACGCCCCACTGGATCATGAAGGAGGCGATTTCCCAGTACGTCGAACGCGAGGAGAAACACGAGGCGTTCC
GGCAAGCCGGGCTCAAGGCGTGGGAGGAGTATCGGGCAACCGGCCAATACGCGCGCCCCGAGGAAGTCGAGGCATGGCTC
GAAAGCTGGGGCACCGAGGATGAACAGCCGGCACCGGAATGCCGGAAATAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|