Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 723472..723967 Replicon chromosome
Accession NZ_CP011366
Organism Salinicoccus halodurans strain H3B36 isolate soil

Toxin (Protein)


Gene name relE Uniprot ID A0A0F7HJX5
Locus tag AAT16_RS03675 Protein ID WP_046789588.1
Coordinates 723698..723967 (+) Length 90 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A0F7HJ87
Locus tag AAT16_RS03670 Protein ID WP_046789587.1
Coordinates 723472..723696 (+) Length 75 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AAT16_RS03640 718549..719190 - 642 WP_046789582.1 RNA polymerase sigma factor -
AAT16_RS03645 719366..719890 + 525 WP_046789583.1 competence protein ComK -
AAT16_RS03650 720003..721592 + 1590 WP_046791427.1 hypothetical protein -
AAT16_RS03655 721582..722382 + 801 WP_046789584.1 hypothetical protein -
AAT16_RS03660 722496..722912 + 417 WP_046789585.1 MarR family transcriptional regulator -
AAT16_RS03665 723137..723370 + 234 WP_143544926.1 hypothetical protein -
AAT16_RS03670 723472..723696 + 225 WP_046789587.1 hypothetical protein Antitoxin
AAT16_RS03675 723698..723967 + 270 WP_046789588.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
AAT16_RS14120 724471..725451 + 981 WP_052749819.1 acyltransferase -
AAT16_RS03685 725609..726418 + 810 WP_046789589.1 ABC transporter permease -
AAT16_RS03690 726432..727583 + 1152 WP_046789590.1 glycosyltransferase family 4 protein -
AAT16_RS03695 727570..727959 + 390 WP_046789591.1 hypothetical protein -
AAT16_RS03700 727943..728566 + 624 WP_046789592.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-87)

Antitoxin

Protein of unknown function DUF6290

(1-72)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10688.51 Da        Isoelectric Point: 10.5690

>T54164 WP_046789588.1 NZ_CP011366:723698-723967 [Salinicoccus halodurans]
MMYRVVYEKKAVKSLSKIDKRQQRMIVSWIEKNLQNATNPKQHGKALQGQLKDYWRYRVGNYRILADIDQDEIKIIIVNI
GHRKDIYKP

Download         Length: 270 bp

>T54164 NZ_CP011366:723698-723967 [Salinicoccus halodurans]
ATGATGTATCGTGTGGTATACGAGAAAAAAGCCGTTAAGAGCCTGTCGAAAATTGACAAACGTCAGCAACGCATGATTGT
CTCTTGGATTGAAAAGAATCTGCAAAACGCCACCAATCCGAAGCAACACGGGAAAGCATTGCAAGGTCAATTAAAGGATT
ACTGGCGCTACCGTGTCGGGAATTATCGAATCCTGGCAGATATTGACCAGGATGAAATCAAAATCATAATTGTTAATATT
GGACATCGTAAAGATATTTATAAACCATAG

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8762.96 Da        Isoelectric Point: 4.0060

>AT54164 WP_046789587.1 NZ_CP011366:723472-723696 [Salinicoccus halodurans]
MGTITVRLNEMEQKVFEEYAKMYDVPLSTLMKQTLEERIEDELDLDAIKAYENQLETDDVTVYEHDEMKKMLGL

Download         Length: 225 bp

>AT54164 NZ_CP011366:723472-723696 [Salinicoccus halodurans]
ATGGGTACAATTACAGTGCGATTGAATGAAATGGAACAAAAAGTATTTGAGGAATACGCAAAAATGTACGATGTGCCTTT
ATCCACCCTTATGAAGCAGACGCTCGAAGAAAGAATAGAAGATGAATTGGATTTAGACGCGATTAAAGCGTATGAAAATC
AGCTTGAGACCGATGATGTCACGGTTTATGAGCATGATGAAATGAAGAAAATGCTGGGTCTGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0F7HJX5

Antitoxin

Source ID Structure
AlphaFold DB A0A0F7HJ87

References