Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pemIK/MazF(toxin)
Location 2368585..2369216 Replicon chromosome
Accession NZ_CP011361
Organism Salimicrobium jeotgali strain MJ3

Toxin (Protein)


Gene name pemK Uniprot ID -
Locus tag AAV35_RS11885 Protein ID WP_008591062.1
Coordinates 2368585..2368935 (-) Length 117 a.a.

Antitoxin (Protein)


Gene name pemI Uniprot ID -
Locus tag AAV35_RS11890 Protein ID WP_008591060.1
Coordinates 2368941..2369216 (-) Length 92 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AAV35_RS11850 2364067..2364849 - 783 WP_008591080.1 RNA polymerase sigma factor SigB -
AAV35_RS11855 2364821..2365300 - 480 WP_008591078.1 anti-sigma B factor RsbW -
AAV35_RS11860 2365300..2365632 - 333 WP_008591075.1 STAS domain-containing protein -
AAV35_RS11865 2365699..2366709 - 1011 WP_008591073.1 PP2C family protein-serine/threonine phosphatase -
AAV35_RS11870 2366726..2367127 - 402 WP_008591070.1 anti-sigma regulatory factor -
AAV35_RS11875 2367131..2367487 - 357 WP_008591068.1 STAS domain-containing protein -
AAV35_RS11880 2367484..2368398 - 915 WP_008591065.1 STAS domain-containing protein -
AAV35_RS11885 2368585..2368935 - 351 WP_008591062.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
AAV35_RS11890 2368941..2369216 - 276 WP_008591060.1 hypothetical protein Antitoxin
AAV35_RS11895 2369313..2370479 - 1167 WP_008591058.1 alanine racemase -
AAV35_RS11900 2370561..2372066 - 1506 WP_008591056.1 NAD(P)H-hydrate dehydratase -
AAV35_RS11905 2372114..2372470 - 357 WP_008591053.1 holo-ACP synthase -
AAV35_RS11910 2372588..2373202 + 615 WP_008591051.1 rhomboid family intramembrane serine protease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(4-111)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 13048.22 Da        Isoelectric Point: 8.5619

>T54152 WP_008591062.1 NZ_CP011361:c2368935-2368585 [Salimicrobium jeotgali]
MMVKRGDVYFADLSPVVGSEQGGVRPVLVLQNDIGNRFSPTVIVAAITAQIQKAKLPTHVEINAEKYQFERNSVILLEQI
RTIDKQRLTDKITHLDESMMLRVNKALQISLGLIDF

Download         Length: 351 bp

>T54152 NZ_CP011361:c2368935-2368585 [Salimicrobium jeotgali]
TTGATGGTCAAACGAGGAGACGTTTATTTCGCTGATTTGTCACCGGTAGTAGGTTCTGAACAAGGGGGAGTCCGCCCTGT
GCTTGTCCTGCAGAACGACATCGGGAACCGTTTCAGCCCCACTGTAATCGTAGCGGCGATTACAGCGCAAATACAAAAAG
CTAAACTGCCTACTCACGTAGAGATCAATGCAGAAAAGTATCAATTTGAACGGAATTCTGTTATATTACTGGAACAAATC
AGAACGATCGATAAACAGCGTTTGACAGACAAGATTACACATCTGGATGAATCGATGATGCTTCGTGTGAACAAAGCCTT
ACAGATCAGTTTGGGGCTTATCGATTTTTAG

Antitoxin


Download         Length: 92 a.a.        Molecular weight: 10654.04 Da        Isoelectric Point: 4.0514

>AT54152 WP_008591060.1 NZ_CP011361:c2369216-2368941 [Salimicrobium jeotgali]
MSESMEEIVLRVPETLLNEVDSYTIEEECDRNDFLCQAIRMYLREKKERQIRESMCQGYMEMAKINLTIASEAFQAEEEA
EHTLEQLVSGV

Download         Length: 276 bp

>AT54152 NZ_CP011361:c2369216-2368941 [Salimicrobium jeotgali]
TTGTCAGAGAGCATGGAGGAAATTGTTCTTAGAGTTCCGGAGACCCTTCTGAACGAAGTGGACAGTTACACAATAGAAGA
AGAGTGCGATCGAAATGATTTTCTTTGTCAGGCAATAAGGATGTATTTGCGTGAGAAAAAAGAACGGCAGATTCGGGAAT
CTATGTGTCAGGGGTATATGGAAATGGCTAAAATCAATCTAACTATCGCTTCAGAAGCTTTCCAGGCTGAAGAGGAGGCG
GAGCACACCCTCGAGCAATTAGTGAGCGGGGTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References