Detailed information of TA system TA054132

Bioinformatically predicted

Overview

TA module

• Type: III
• Classification (family/domain): toxIN/ToxN(toxin)
• Location: 79566..80308
• Replicon: plasmid pYC3
• Accession: NZ_CP011351
• Organism: Bacillus thuringiensis strain YC-10

Toxin (Protein)

• Gene name: toxN
• Uniprot ID: -
• Locus tag: XI92_RS33200
• Protein ID: WP_016097319.1
• Coordinates: 79566..80150 (-)
• Length: 195 a.a.

Antitoxin (RNA)

Gene name	toxI
Locus tag	-
Coordinates	80212..80308 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
XI92_RS33180	74972..75418	-	447	WP_016097323.1	CPBP family intramembrane metalloprotease	-
XI92_RS33185	75448..77589	-	2142	WP_016097322.1	type IA DNA topoisomerase	-
XI92_RS33190	77710..78090	-	381	WP_016097321.1	hypothetical protein	-
XI92_RS33195	78197..79498	-	1302	WP_016097320.1	hypothetical protein	-
XI92_RS33200	79566..80150	-	585	WP_016097319.1	type III toxin-antitoxin system ToxN/AbiQ family toxin	Toxin
-	80212..80308	-	97	NuclAT_0	-	Antitoxin
-	80212..80308	-	97	NuclAT_0	-	Antitoxin
-	80212..80308	-	97	NuclAT_0	-	Antitoxin
-	80212..80308	-	97	NuclAT_0	-	Antitoxin

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..80704	80704

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• ToxN/AbiQ toxin (8-169)

Sequences

Toxin

Protein

• Length: 195 a.a.
• Molecular weight: 22900.17 Da
• Isoelectric Point: 8.9694

>T54132 WP_016097319.1 NZ_CP011351:c80150-79566 [Bacillus thuringiensis]
MANKDNPKFYTISTEYIDYLRETDSKVPFNKDEQHSRPYVGVLEKINGHDYFVPLTSRNDKNFNSQVSVKLFDTDEKRIG
VLLVNNMIPVPEKECKEIDIAEKTAADPQYGNLMLKQYLFLKENMDRVTNKVEKVYKDVTVQGKPSHKQKFLKGVCCDFP
KLEEKCQEYKERDQAKERDKARRIAYMRQMGRER

Nucleotide

• Length: 585 bp

>T54132 NZ_CP011351:c80150-79566 [Bacillus thuringiensis]
TTGGCTAATAAAGATAATCCTAAATTCTACACCATTTCAACTGAATATATAGATTATTTAAGAGAAACGGATAGTAAAGT
ACCTTTTAATAAAGATGAACAGCATAGTAGACCGTATGTAGGTGTATTGGAAAAAATCAATGGTCATGATTATTTTGTAC
CTTTAACATCACGTAACGATAAAAATTTTAACAGTCAGGTCAGTGTGAAATTATTCGATACTGATGAAAAGCGAATTGGA
GTTTTATTGGTTAATAACATGATTCCAGTCCCAGAAAAAGAGTGTAAAGAAATTGATATAGCAGAAAAAACAGCAGCAGA
CCCTCAGTATGGTAATTTGATGTTAAAACAGTATTTATTTTTAAAAGAAAATATGGATCGAGTTACTAATAAAGTGGAAA
AAGTATATAAAGATGTAACTGTACAAGGAAAGCCTTCACATAAACAAAAATTCTTAAAAGGAGTTTGTTGTGATTTCCCT
AAATTAGAAGAAAAGTGCCAAGAATATAAAGAAAGAGATCAAGCTAAAGAAAGAGATAAAGCTAGAAGAATAGCATATAT
GCGTCAAATGGGGCGTGAGAGATAA

Antitoxin

Nucleotide

• Length: 97 bp

>AT54132 NZ_CP011351:c80308-80212 [Bacillus thuringiensis]
GTAACCTTACTTTAGTAGGTGCGAAAAAATTGGTGTAACTCTACCGTAGTGAGTACCAAAAAATTGGTGTAGCCTTACCG
TAGTAGGCGCTAAAAAA

Structures

Antitoxin