Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-CC2985
Location 1699470..1700004 Replicon chromosome
Accession NZ_CP011344
Organism Citromicrobium sp. JL477

Toxin (Protein)


Gene name parE Uniprot ID A0A8D4CKP4
Locus tag WG74_RS08130 Protein ID WP_010238641.1
Coordinates 1699714..1700004 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID A0A8D3Z0H4
Locus tag WG74_RS08125 Protein ID WP_010238642.1
Coordinates 1699470..1699721 (+) Length 84 a.a.

Genomic Context

WG74_RS08100WG74_RS08105WG74_RS08110WG74_RS08115WG74_RS08120WG74_RS08125WG74_RS08130WG74_RS08135WG74_RS16435WG74_RS08140WG74_RS08145WG74_RS08150
Location: 1694879..1695517 (639 bp)
Type: Others
Protein ID: WP_010238654.1
Location: 1695514..1696422 (909 bp)
Type: Others
Protein ID: WP_010238653.1
Location: 1696501..1697427 (927 bp)
Type: Others
Protein ID: WP_010238650.1
Location: 1697713..1698741 (1029 bp)
Type: Others
Protein ID: WP_192807553.1
Location: 1698917..1699438 (522 bp)
Type: Others
Protein ID: WP_010238644.1
Location: 1699470..1699721 (252 bp)
Type: Antitoxin
Protein ID: WP_010238642.1
Location: 1699714..1700004 (291 bp)
Type: Toxin
Protein ID: WP_010238641.1
Location: 1700285..1701397 (1113 bp)
Type: Others
Protein ID: WP_010238640.1
Location: 1704434..1704574 (141 bp)
Type: Others
Protein ID: WP_010238636.1
Location: 1701402..1702160 (759 bp)
Type: Others
Protein ID: WP_010238639.1
Location: 1702221..1702736 (516 bp)
Type: Others
Protein ID: WP_010238638.1
Location: 1702817..1704235 (1419 bp)
Type: Others
Protein ID: WP_010238637.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
WG74_RS081001694879..1695517+639WP_010238654.1ribonuclease HII-
WG74_RS081051695514..1696422+909WP_010238653.1SDR family NAD(P)-dependent oxidoreductase-
WG74_RS081101696501..1697427+927WP_010238650.1calcium/sodium antiporter-
WG74_RS081151697713..1698741+1029WP_192807553.1site-specific DNA-methyltransferase-
WG74_RS081201698917..1699438+522WP_010238644.1hypothetical protein-
WG74_RS081251699470..1699721+252WP_010238642.1type II toxin-antitoxin system ParD family antitoxinAntitoxin
WG74_RS081301699714..1700004+291WP_010238641.1type II toxin-antitoxin system RelE/ParE family toxinToxin
WG74_RS081351700285..1701397+1113WP_010238640.1dihydropteroate synthase-
WG74_RS081401701402..1702160-759WP_010238639.1SDR family oxidoreductase-
WG74_RS081451702221..1702736-516WP_010238638.1hemerythrin domain-containing protein-
WG74_RS081501702817..1704235-1419WP_010238637.1sigma-54 dependent transcriptional regulator-
WG74_RS164351704434..1704574+141WP_010238636.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-92)

Antitoxin

Antitoxin ParD

(7-81)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11107.68 Da        Isoelectric Point: 7.3597

>T54124 WP_010238641.1 NZ_CP011344:1699714-1700004 [Citromicrobium sp. JL477]
VRELRLTRKAAADLSDIADFTIAEFGIEQAGRYRDQFARCFASLLDNPFLGRSANELAPGLRRIRQQAHVVFYQPSEEVI
LVVRVLHHRMDFEQHL

Download         Length: 291 bp

>T54124 NZ_CP011344:1699714-1700004 [Citromicrobium sp. JL477]
GTGCGTGAGCTGCGGCTGACCCGAAAGGCGGCGGCCGATCTCTCCGACATTGCCGATTTTACCATTGCCGAGTTCGGGAT
CGAGCAGGCGGGCAGGTATCGCGACCAGTTCGCCAGATGCTTCGCCTCGCTGCTCGACAATCCCTTTTTGGGGCGAAGCG
CGAACGAACTCGCGCCCGGTTTGCGGCGTATCCGGCAGCAGGCGCATGTCGTGTTCTACCAGCCCTCGGAAGAGGTGATT
CTAGTTGTCCGCGTGCTCCACCACCGAATGGATTTCGAGCAGCATTTGTAG

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9296.27 Da        Isoelectric Point: 4.6461

>AT54124 WP_010238642.1 NZ_CP011344:1699470-1699721 [Citromicrobium sp. JL477]
MATIRKTITLSDTQDAWIKRQIAEGGFTNDSEYIRDLVRRDQEGQEKLSGLRQAIAEGLDSGVSDRSLDDIWTEAEKRAA
ARA

Download         Length: 252 bp

>AT54124 NZ_CP011344:1699470-1699721 [Citromicrobium sp. JL477]
ATGGCCACCATCCGCAAGACCATCACGCTCAGCGACACGCAGGACGCGTGGATCAAGCGTCAGATTGCTGAGGGCGGGTT
CACCAACGACAGCGAATATATCCGCGATCTCGTCCGCCGCGATCAGGAGGGGCAGGAGAAGCTGTCCGGGTTGCGGCAGG
CGATTGCCGAGGGGCTGGACAGCGGCGTGAGCGACCGCTCGCTCGACGACATCTGGACCGAGGCAGAGAAGCGCGCAGCC
GCCCGTGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References