Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-Phd
Location 148234..148787 Replicon chromosome
Accession NZ_CP011341
Organism Rhodococcus aetherivorans strain IcdP1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag AAT18_RS00640 Protein ID WP_050034317.1
Coordinates 148506..148787 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag AAT18_RS00635 Protein ID WP_050034316.1
Coordinates 148234..148509 (+) Length 92 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AAT18_RS00615 143978..145090 - 1113 WP_003934731.1 LLM class flavin-dependent oxidoreductase -
AAT18_RS00620 145149..145964 - 816 WP_050034313.1 alpha/beta hydrolase -
AAT18_RS00625 145984..146898 - 915 WP_050034314.1 catechol 2,3-dioxygenase -
AAT18_RS26670 146846..147301 - 456 WP_081608696.1 2Fe-2S iron-sulfur cluster binding domain-containing protein -
AAT18_RS00630 147298..147753 - 456 WP_082120304.1 flavin reductase family protein -
AAT18_RS00635 148234..148509 + 276 WP_050034316.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
AAT18_RS00640 148506..148787 + 282 WP_050034317.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
AAT18_RS00645 149435..149957 - 523 Protein_132 hypothetical protein -
AAT18_RS00650 151370..152845 - 1476 WP_050034318.1 glyceraldehyde-3-phosphate dehydrogenase -
AAT18_RS00655 153328..153558 + 231 Protein_134 DUF4192 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(37-91)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(3-73)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10466.97 Da        Isoelectric Point: 9.7863

>T54049 WP_050034317.1 NZ_CP011341:148506-148787 [Rhodococcus aetherivorans]
MTDEAPAPYDVAIASPARRALSRLPGRIVHAVVEFISGPLAENPHRLSTPLRNDLAGLRSARRGDYRILLRVDDDHRTIL
IVDIDHRAHIYRP

Download         Length: 282 bp

>T54049 NZ_CP011341:148506-148787 [Rhodococcus aetherivorans]
ATGACCGATGAGGCGCCGGCACCCTACGACGTCGCGATCGCCTCACCGGCCCGCCGAGCCCTGTCCCGACTACCGGGACG
GATCGTGCATGCCGTCGTCGAATTCATCTCCGGCCCCCTGGCGGAGAATCCCCACCGGCTGAGCACACCGCTGCGCAACG
ATCTCGCAGGCCTGCGCAGTGCCCGGCGCGGCGACTACCGCATCCTGCTCCGTGTCGACGACGACCACCGCACCATCCTG
ATCGTCGACATCGACCACCGCGCCCACATCTACCGACCCTGA

Antitoxin


Download         Length: 92 a.a.        Molecular weight: 9719.86 Da        Isoelectric Point: 4.8210

>AT54049 WP_050034316.1 NZ_CP011341:148234-148509 [Rhodococcus aetherivorans]
VTTVPLGEAKDKLSALVDSAEATHDIITITRHGKPAAVLMSADDLESLHETIYWLSRPGTAESVAVADREYAAGRTASLD
EVRAEHGLPPR

Download         Length: 276 bp

>AT54049 NZ_CP011341:148234-148509 [Rhodococcus aetherivorans]
GTGACGACGGTACCGCTCGGCGAAGCCAAGGACAAGCTCTCGGCGCTGGTGGACAGTGCCGAGGCCACGCACGACATCAT
CACGATCACCCGGCACGGCAAACCGGCCGCGGTCCTGATGTCGGCCGACGATCTGGAATCACTGCACGAGACGATCTACT
GGCTGTCTCGGCCCGGCACCGCCGAGTCGGTCGCGGTCGCCGACCGCGAGTACGCCGCCGGCCGGACCGCCTCGCTCGAC
GAGGTGCGCGCCGAGCACGGCCTGCCGCCCCGATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References